People with CD4
cell counts below 350 per millilitre of blood can now be treated.
The patients were in category C - 3 with CD4
cell counts below 200 and each had at least one case of AIDS - defining illness.
Not exact matches
One of the studies, published in 2008, suggested that patients whose antiretroviral treatment was deferred until their CD4
cell counts were
below 250 were at greater risk of opportunistic infection than those that received antiretroviral treatment when CD4
cell counts were higher than 350.
Instead of a CD4
cell count of 200, the threshold which the WHO recommended in its 2006 guidelines for HIV treatment, a CD4
cell count at or
below 350 should be the cutoff, the agency now advises.
The MIT team estimated that if there were a way to detect when patients» white
cell counts went
below the threshold level, so they could be treated with prophylactic antibiotics and drugs that promote white blood
cell growth, about half of the 110,000 infections that occur in chemotherapy patients in the United States every year could be prevented.
The technology does not provide a precise
count of white blood
cells, but reveals whether patients are above or
below the threshold considered dangerous — defined as 500 neutrophils (the most common type of white blood
cell) per microliter of blood.
In the other, infected partners deferred treatment until their CD4 T
cells (the immune
cells the virus targets) fell to a perilous
count below 250, or until they suffered an AIDS - related illness.
By carefully measuring individual laborers» exposure to benzene and other chemicals, the researchers showed that the 109 workers exposed
below the 1 ppm level still had white blood
cell counts almost 15 percent lower than similar workers who were not exposed.
For instance, recent trials show that if people are treated when their blood contains 350 to 500
cells per cubic millimetre, their risk of transmitting the virus is 96 per cent lower than if they begin treatment when their
counts fall
below 350.
AIDS is diagnosed when the CD4
count falls
below 200
cells per cubic millimeter of blood.
Low White Blood
Cell Count: The white blood cell count is expected to drop below normal after treatment, but will return to normal by the next treatm
Cell Count: The white blood cell count is expected to drop below normal after treatment, but will return to normal by the next treat
Count: The white blood
cell count is expected to drop below normal after treatment, but will return to normal by the next treatm
cell count is expected to drop below normal after treatment, but will return to normal by the next treat
count is expected to drop
below normal after treatment, but will return to normal by the next treatment.