«It will be exciting to explore
how cell culture conditions enhance the zygote's intrinsic surveillance and repair mechanisms, thus leading to better quality embryos and potentially more successful pregnancies.»
«What made the difference are our
unique cell culture conditions and 3 - D matrix, which allowed cells to grow and develop much faster and longer than the 2 - D culture approaches that are more typically used.»
Most of these were invalidated when challenged with experimental data generated in Smith's laboratory, which measured gene expression of ESCs across 23
different cell culture conditions, all of which maintained pluripotency.
«In the future, this will move us towards a way to understand how to generate a cardiac muscle or other specific cell type without having to try an unwieldy number
of cell culture conditions.»
Furthermore, the proliferation - inactivated MEF cells usually function well only for 5 — 7 days under ES or
iPS cell culture conditions.
The ~ 48 % UV - UDS value presented in this study for XpdTTD / TTD cells differs from our previously published data of 25 % UV - UDS [21], possibly because of the high variability intrinsic to the assay or routine variations in
the cell culture conditions.