Studies of IBD are typically performed
using cell culture experiments or animal models, which don't mimic the precise conditions that occur in the gut of human patients.
Over the course of the two - month breeding season, Grouse Park provided 72 eggs for germ -
cell culturing experiments at Crystal Bioscience's laboratories.
Using, inter alia,
cell culture experiments, the scientists were also able to determine why the concentration of the CCL21 signpost molecules increases in the direction of the lymph nodes.
But everyone agrees that there are problems with
the cell culture experiments.
The cell culture experiments showed that MAbs prevented the uptake of misfolded α - syn fibrils by neurons and sharply reduced the recruitment of natural α - syn into new Lewy body aggregates.
«They had pretty good evidence, based on animal and
cell culture experiments, that the off - target effects wouldn't be such a high risk that [the trial] was not worth trying,» says Hammarskjold, who is at the University of Virginia School of Medicine in Charlottesville.
DS carried out
cell culture experiments and JLE performed DNA microarray assay and corresponding data analysis.
Finally, we thank Dr. Alisson M. Gontijo and his lab members for supporting
the cell culture experiments.