Sentences with phrase «cell cultures»

The findings were made in cell cultures.

The results showed: cell death increased in relation to the particle dose with all cell cultures.

When he genetically disabled or chemically modified the HSPGs in cell cultures and in a mouse model, clumps of tau could not enter cells, thus inhibiting the spread of misfolded tau from cell to cell.

Brown University engineers have demonstrated a technique for making 3 - D - printed biomaterials that can degrade on demand, which can be useful in making intricately patterned microfluidic devices or in making cell cultures than can change dynamically during experiments.

The study, published in Nature Communications, examined the changes that occur in cancer cells as they break away from tumours in cell cultures, zebrafish and mice.

This surface protein, which has not yet been named, also binds to normal PrP both in protein assays and in cell cultures.

It described the growth in cell cultures of the virus that causes AIDS, a breakthrough which led eventually to a blood test for HIV infection.

The study was developed by means of experiments carried out with cell cultures of patients with Niemann - Pick disease.

Experiments on cell cultures from patients with malignant melanoma confirmed the new results.

In that temporary cell cultures the process of reaggregation further takes place.»

Cell - based biosensors measure changes in cell cultures via electrical signals.

That's an advantage for drug tests over flat - dish cell cultures currently used because it more accurately represents living tissue and more of the test cells can be kept alive by vessel - supplied nutrients.

The scientists then tried the proline / polyproline combination in a test system of adherent cell cultures that were subjected to freeze - thaw conditions.

They tested the system on cell cultures, and then in live mice with breast cancer and mice with constricted arteries in their legs.

«We're seeing that some of these factors have a major impact on cell behavior that is not possible to observe in conventional 2D cell cultures.»

The researchers, working with cell cultures, first observed how individual tumour cells kill specific cells in the vascular wall, called endothelial cells.

Initially, the researchers placed the fragments on a gel and soaked them in fetal bovine serum, a typical ingredient of cell cultures.

Researchers rushed to the building the morning after the quake to wade through chemical - laced water and salvage cell cultures, enzymes, antibodies, and other frozen samples and reagents, bringing some home to their kitchen freezers.

People use organic solvents and synthetic polymers as additives to prevent cell cultures from freezing damage.

This is the reason why haploid cell cultures do not thrive.

In the West, these have been replaced by safer, more effective vaccines grown in cell cultures.

However, Eggan and McCarroll emphasized that now that this phenomenon has been found, inexpensive gene - sequencing tests will allow researchers to identify and remove from the production line cell cultures with concerning mutations that might prove dangerous after transplantation.

For the most critically endangered species there should, I believe, be far more effort to preserve viable cell cultures from as many different individuals as possible.

An experimental drug that targets abnormally high levels of a protein linked to cancer growth appears to significantly reduce the proliferation of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results of a study led by Johns Hopkins scientists.

In the new research — published Oct. 21 in the early online edition of Proceedings of the National Academy of Sciences - Margeta, former postdoctoral associate Agata Habas, PhD, now at UC San Diego, and colleagues teased apart the relative contributions of neurons and astrocytes in Nrf2 signaling by performing experiments on cell cultures containing predominantly neurons, predominantly astrocytes, or a mixture of both.

Together, Raman says, this dual - mode treatment produced cell - killing results that paralleled their experiments in cell cultures.

When Oudhoff applied human saliva to skin - cell cultures scratched by a needle, however, he found that the concentrations of growth factors were too low to have any therapeutic effect.

The long - term facilitation of synaptic efficacy that is induced by serotonin in dissociated cell cultures of sensory and motor neurons of Aplysia is accompanied by the growth of new synaptic connections.

Its Frozen Zoo contains cell cultures from more than 800 species.

In a paper published in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatments.

By activating the Ret receptor, the scientists were able to prevent in flies and human cell cultures the degeneration of mitochondria, which is caused by a gene defect related to Parkinson's disease.

And unlike current anti-HIV drugs, Ciclopirox completely eradicates infectious HIV from cell cultures, with no rebound of virus when the drug is stopped.

In BRIC 17 - 1, cell cultures derived from thale cress plants are grown in Petri dishes and later examined to determine which genes are involved in certain cellular changes.

According to McCague, «the rarity of human prostate cancer cell cultures makes studying tamandron's potential difficult in the test tube.»

Exposing cell cultures to purified melittin, they reported that the compound completely inhibited Borrelia growth.

When the researchers used gene engineering techniques to knock out DDX3 expression in laboratory - grown cell cultures that highly expressed this protein, cell proliferation was half that of cell cultures with high DDX3 expression.

To shock the plants, Cuello applied a 30 to 100 milliamp current to the growth - medium of plants grown hydroponically, or, in the case of barrel medic, to the solution surrounding the cell cultures.

The research showed the beta - lactamase genes in Klebsiella pneumoniae were on all the time, whether or not the bacteria were infecting human cell cultures.

Set up experiments for whole week: Start cell cultures, book microscopes, make buffers, and even find time over the bacterial incubator for a spot of eyelash fluttering at the sexy postdoc in the lab next door.

Using cell cultures, the research team also found two ways to prevent the toxicity caused by alpha - synuclein: gene therapy that forced the neurons to make more TOM20 protein protected them from the alpha - synuclein; and a protein that was able to prevent alpha - synuclein from sticking to TOM20 prevented alpha - synuclein's harmful effects on mitochondria.

Similar shock treatments applied to cell cultures of barrel medic (Medicago truncatula)-- a plant similar to alfalfa — yielded a 168-fold increase in production of one chemical and at least a two-fold increase in 54 other compounds.

They showed in previous studies with cell cultures that when adding RK - 33 to malignant lung and other cancerous cells that highly express DDX3, proliferation slowed or halted, and the cells» ability to form colonies was impaired.

The next task will be to engineer neurons in cell cultures so that they manifest one or more of the variants.

That's why the firm has turned to cellular agriculture, in which crops are made from cell cultures.

In their work, the researchers also show how TGF - beta can be used in stem cell cultures to mass - produce nerve cells which in turn produce the signalling substance serotonin.

In the current study, Lasmézas and her team looked at cell cultures of neurons that were induced to accumulate fibrils made of misfolded α - synuclein, mimicking Lewy bodies in patients with Parkinson's.

The visual appearance of cell cultures also resembled that of the corresponding fresh fruits.

She uses lab models, including cell cultures and mice, to study these diseases.

In this study, she and her colleagues used cell cultures collected from 16 patients in the United States and Europe to search for drugs that could kill or stop the growth of DIPG cells.

A Freiburg - based research group has developed a microfluidic chip where more than one hundred apidose - derived adult stem cell cultures can grow and divide.