LA JOLLA, CA — A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in
cell cycle control leads to the proliferation of cancer cells.
Not exact matches
The work has
led him to explore the role of protein phosphorylation in a diverse array of cellular functions, including transformation,
cell communication,
cell adhesion,
cell -
cycle regulation, the
control of gene expression, and protein degradation.
Like in the Wnt signaling pathway, ligands bind to the EGFR on the
cell surface and initiate a cascade of events in the
cell that in this case
lead to regulation of genes that
control cell cycle progression.