Sentences with phrase «cell cycle progression from»
Inhibition of mTOR expression or function blocked cell cycle progression from G1 to S phase associated with modulation of the CDK inhibitors p21waf1 and p27kip1.
http://cancerres.aacrjournals.org/ Not exact matches
Tumour cells are «glutamine - addicted» [1,2] because glutamine is coupled to mechanistic target of rapamycin (mTOR) signalling, which integrates signals from growth factors, energy status and amino acid nutrition and co-ordinates these signals with cell growth, cell cycle progression and antioxidant machinery [3].