Currently we are using new transgenic approaches to mark and isolate the proliferating cardiomyocytes and we generate single - cell transcriptomics and regulomics data to identify the mechanisms inducing
cell cycle re-entry.
In detail, currently we investigate the underlying mechanisms that may lead to
cell cycle re-entry, so that Müller glia divide to self - renew and generate progenitor and neuronal progeny (see Figure).
Static mechanical strain induces capillary endothelial
cell cycle re-entry and sprouting.
Not exact matches
The authors discovered that FGF2 treatment forced a high percentage of astrocytic
cell -
cycle re-entry via FGF receptor - induced phosphorylation of ERK and mediated the generation of self - renewing Nestin - expressing NSCs.