Sentences with phrase «cell cycle regulation of»

Activation of the cdk inhibitory protein p21 by ellagic acid suggests a role for ellagic acid in cell cycle regulation of cancer cells.

The results reveal the central role of protein phosphorylation in the atypical cell cycle regulation of a divergent eukaryote.

Maria Anna Ciemerych began her research with studies focusing at the cell cycle regulation of mouse oocytes and preimplantation embryos (Ph.D. at the University of Warsaw), then investigated the role of the cell cycle regulators - D - type cyclins, in mouse development (Dana Farber Cancer Institute, Harvard Medical School).

Not exact matches

He spent his last year as a Lisbon student studying cell - cycle regulation in yeast at the University of Manchester in the United Kingdom, with an Erasmus scholarship from the European Commission.

Although the regulation of this gene has a strong «cell cycle control» component, I was more interested in studying cell cycle regulation «proper.»

The researchers said the findings fundamentally change the understanding of G1 cell cycle regulation and the molecular origins of many associated cancers.

Such precise regulation of the cell cycle is lost in cancer cells.

CDKs are crucial for the regulation of the cell cycle.

When Corry and first author Wen Lu, a graduate student in immunology, sought to determine how the microRNA worked, they found histone deacetylase 4, a protein that plays a role in the regulation of DNA transcription, cell cycle and development.

Other studies have shown that the virus is capable of moving into brain cells, modifying the regulation of the cell cycle, and inducing their death.

Hypermethylation of DNA is a key epigenetic mechanism for the silencing of many genes, including those for cell cycle regulation, receptors, DNA repair, and apoptosis (5, 6, 7, 8).

Cell cycle - dependent regulation of the forkhead transcription factor FOXK2 by CDK - cyclin complexes.

«We suspect that faults in cell - cycle regulation account for a variety of developmental brain diseases.»

Anil Belur Nagaraj (Bornhäuser, TUD)-- «Understanding the regulation of tumor cell cycle to identify and characterize factors that negatively regulate the tumor phenotype.»

The work has led him to explore the role of protein phosphorylation in a diverse array of cellular functions, including transformation, cell communication, cell adhesion, cell - cycle regulation, the control of gene expression, and protein degradation.

Activated ERK1 / 2 modulates the functions of several transcription factors, protein kinases, protein phosphatases, cytoskeletal proteins, signaling molecules, apoptosis - related proteins, as well as other types of proteins [32], while activated AKT modulates the function of numerous substrates involved in the regulation of cell survival, cell cycle progression and cellular growth [33, 34], whereas JNK acts as pro-apoptotic as well as anti-apoptotic depending on the conditions [35].

The Galli group studies the regulation of the cell cycle during development and tissue formation.

Polleux F., Dehay C., Moraillon B. and Kennedy H. (1997) Regulation of neuroblast cell - cycle kinetics plays a crucial role in the generation of unique features of neocortical areas.

Stathmin is essential for the regulation of the cell cytoskeleton, which is required for numerous cell processes including regulating the cell cycle, cytoplasmic organization, cell division and cell motility...

However, we can not suspect any abnormal effect on parthenotes due to the aberrant expression of CCNA1 since the protein is not expressed at the blastocyst stage [33], and its cell cycle regulation role is limited in meiotic cells [34].

Here, we are focusing on the regulation of the cell cycle that seems to prevent clonal growth of premalignant stages compared to active myeloma.

The A. queenslandica genome allows us to assess systematically the origin of the six hallmarks of metazoan multicellularity: (1) regulated cell cycling and growth; (2) programmed cell death; (3) cell — cell and cell — matrix adhesion; (4) developmental signalling and gene regulation; (5) allorecognition and innate immunity; and (6) specialization of cell types.

Like in the Wnt signaling pathway, ligands bind to the EGFR on the cell surface and initiate a cascade of events in the cell that in this case lead to regulation of genes that control cell cycle progression.

In response to cellular stress such as DNA damage, oncogene activation, transcriptional inhibition, and hypoxia, tumor suppressor p53 is activated and expressed, and acts as a transcription factor to induce its target genes [1], thereby playing a central role in the regulation of DNA repair, cell cycle, apoptosis, senescence, and angiogenesis [2 - 4].

Forman - Kay has also found cases where disordered proteins provide precise tuning of cell cycle regulation and protein degradation.

After twenty years of research, the cohesin complex still manages to surprise us regularly, as new functions in new areas of cell cycle regulation come to light.

45) * Coe BP, * Lockwood WW, Girard L, Chari R, MacAulay C, Lam S, Gazdar AF, Minna JD, Lam WL (2006) Differential regulation of cell cycle pathways in small cell and non-small cell lung cancer.

In addition to this, the gene duplicates in zebrafish display strikingly different expression during the day - night cycle, presumably to allow efficient regulation of photoreceptor cells under dramatically different light conditions.

EGCg has been scientifically demonstrated to assist in maintaining healthy tissues during times of normal metabolic stress and to support proper cell cycle regulation.

Melanopsin cells in mammals are specialized for measuring ambient illumination, contributing to visual discrimination [8,9], and driving a wide variety of physiological responses including, but not restricted to: synchronization of circadian clocks to light: dark cycles, regulation of pupil size, modulation of sleep and suppression of pineal melatonin production [10 — 14].