It is far more likely, however, that the egg -
cell cytoplasm with its stripping factor will reprogram all the genetic material including the alterations made in the donor nucleus that were intended to prevent the creation of the zygote.
Not exact matches
The key discovery made by the CSHL team is that FER is able to activate a receptor on the surface of ovarian
cells «from below,» as it were — by interacting
with a portion of the receptor that penetrates the
cell membrane and plunges into the
cytoplasm.
When Gillian Bates at Guy's Hospital, London and Stephen Davies at University College in London and their colleagues examined the brains of transgenic mice endowed
with a DNA encoding 150 of these glutamine repeats, they found that the protein started out, at birth, in the
cytoplasm of the animals» brain
cells and then gradually migrated to
cell nuclei and clumped there.
The virus must then fuse
with the lysosome membrane to escape into the host
cell's
cytoplasm, where it can multiply.
The female egg
cell is a huge biochemical universe unto itself,
with a complex and sophisticated
cytoplasm.
The
cytoplasm of any
cell is swimming
with ribosomes, RNA polymerases, tRNA and mRNA molecules and enzymes, all carrying out their reactions independently of each other.
As seen in Figure 2, the abnormal BM
cells were found to exhibit eccentric, large, round - to - oval / convoluted nuclei
with mostly fine chromatin and prominent nucleoli and moderate - to - abundant gray
cytoplasm with several
cells exhibiting multiple diminutive cytoplasmic vacuoles.
The researchers also examined the subcellular localization of ApoE proteins in human neuroblastoma
cells transfected
with either ApoE3 or ApoE4, detecting the molecules in both the
cytoplasm and the nucleus.
Immunofluorescent imaging of human
cells (U2OS)
with ab7291 reveals a delicate network of alpha - tubulin (green) located exclusively in the
cytoplasm.
HE - stained, non-infected DEF control (A); HE stained infected
cells, 52 hrs post-infection, showing
cell disruption
with a large number of red - stained particles (B); Non-infected Vero
cell monolayer (C); Infected Vero
cells rounded up and focal detachment 60 hrs post-infection (D); Thin section of the infected
cell, 24 hrs post-infection, showing dense particles (white arrow head) and virions (arrow) within the vesicles in the
cytoplasm (N, nucleus).
The iPSC colonies were morphologically indistinguishable from hESCs, forming tight colonies of
cells with a large nucleus to
cytoplasm ratio and prominent nucleoli (Fig. 2E), and they did not display the NSCs» original
cell morphology (Fig. 2F).
When found in tumor
cell membranes, HER2 correlates
with a better prognosis than when it is in the
cytoplasm or nucleus.
Jellyfish have symbiotic relationships
with living things of all sizes, from fish and shrimp that feed off them or off the pieces of food left between their tentacles, to single -
celled photosynthesizing organisms that take shelter inside the
cytoplasm of the jellyfish's
cells.
This process, known as gene expression, begins
with transcription, in which a molecule called messenger RNA transfers the information in DNA out of the
cell's nucleus and into the
cytoplasm, where it is translated into amino acids that form proteins.
Both of these lines of evidence suggest that the issue may be
with the mitochondria or the
cytoplasm of the
cell rather than the
cell nucleus, which is what the traditional view of cancer is.
Transmission electron microscopy
with colloidal gold immunocytochemistry showed structural damage in young and aged microvessel endothelium of ApoE4 animals extended to the
cytoplasm of perivascular
cells, perivascular nerve terminals and hippocampal neurons and glial
cells.