«This one - two punch of discoveries underscores the critical value of basic science — by uncovering the major cause of CD4 T
cell depletion in AIDS, Dr. Greene's lab has been able to identify a potential new
therapy for blocking the disease's progression and improving on current antiretroviral medications.»
Researchers found the gene
therapy approach had stronger results when used in combination with either
depletion of immunosuppressive
cells from the tumor mass or with immune checkpoint blockade.