Sentences with phrase «cell destruction in»

The etiology of β - cell destruction in diabetic dogs is often unknown, although there is evidence that it is frequently caused by immune - mediated processes similar to human type 1 diabetes (70 — 72,82 — 84).

This knowledge is used to engineer synthetic compounds to stimulate cell destruction in cancer cells, or delay cell destruction in neurodegenerative diseases and stroke.

Not exact matches

If we are against the use of stem cell research on the basis of embryonic destruction, shouldn't we also be against in - vitro fertilization clinics because there are always excess embryos that get discarded?

That balance has changed considerably in the past few years, as alternative avenues of stem - cell science have opened up and it increasingly seems like whatever therapeutic potential such cells may someday have could be explored and achieved without the destruction of embryos.

It is in this sense» and only this sense» that the stem - cell wars are over: The central cause of battle, the destruction of human embryos, is no longer necessary or even most useful.

For example, ten or twenty years from now, the physician's tools may include embryonic stem cells or products obtained from cloned embryos and fetuses gestated for that purpose, making physicians who provide such treatments complicit in the life destruction required to obtain the modalities.

It is often caused by the destruction of the insulin - producing cells of the pancreas resulting in an insulin deficiency.

Jaundice which is due to the rapid, abnormal destruction of the baby s blood cells often resulted, in the past, in serious injury or even death for the baby, but this is different from what most babies are now experiencing.

«Advancements in science and research have moved faster than the debates among politicians in Washington, D.C., and breakthroughs announced in recent years confirm the full potential of stem cell research can be realized without the destruction of living human embryos,» House Minority Leader John Boehner, R - Ohio, said Sunday.

In his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNIn his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNin three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNA.

The researchers showed that the synapse - eating process requires a protein in the complement system — a part of the immune response that helps «tag» unwanted cells and other debris for destruction.

In yesterday's order, Lamberth wrote that they did not: «The prior [Bush Administration] guidelines, of course, allowed research only on existing stem cell lines, foreclosing additional destruction of embryos.»

The payload kills cells by means other than genetic destruction, in contrast to the current standard treatments.

In rare cases the bite also can cause a severe illness called systemic loxoscelism, characterized by a blood clotting disorder and hemolysis, destruction of red blood cells.

Type 1 diabetes, formerly known as juvenile diabetes, is characterized by the immune system's destruction of the beta cells in the pancreas.

At first the virus seems to build up harmlessly in brain cells, but as soon as the larva breaks out, these cells burst open, unleashing destruction all around them.

Malaria parasites, which are transmitted through the bite of an infected mosquito, cause the most destruction during the part of their life cycle when they dwell in red blood cells circulating through the body.

In particular, it has evolved to show itself three to nine months after infection, allowing its own destruction by displaying antigens on its cell surfaces so the dog's immune system can destroy it.

New findings published in the Proceedings of the National Academy of Sciences showed in lab studies that supplementing an epigenetic cancer drug called decitabine with vitamin C enhanced the drug's ability to impede cancer cell growth and trigger cellular self - destruction in cancer cell lines.

In August, federally funded work on stem cells was temporarily suspended after a judge ruled that work on hESCs violates a legal amendment in 1995 forbidding funding of any experiments that involve destruction of human embryoIn August, federally funded work on stem cells was temporarily suspended after a judge ruled that work on hESCs violates a legal amendment in 1995 forbidding funding of any experiments that involve destruction of human embryoin 1995 forbidding funding of any experiments that involve destruction of human embryos.

Researchers at Cold Spring Harbor Laboratory in New York have discovered that a protein called Importin - 11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus.

This is characterised by the targeted strengthening of the body's own immune cells, unlike in chemotherapy, in which the aim is direct destruction of the cancer cells.

Semenza says methylation leads to the destruction of NANOG's mRNA so that no protein is made, which in turn causes the embryonic stem cells to abandon their stem cell state and mature into different cell types.

Faith and the embryo Biochemist Paul Berg suggests in April's Discover Dialogue [«Bio Brain Backs Stem Cells»] that only religious faith makes the judgment that the destruction of a human embryo destroys a human individual.

Therefore, these «self - reactive» T cells survive destruction within an organ called the thymus, the central immune organ in which T - cells mature, and attack healthy cells and tissues, including melanocytes.

LOCKED IN Red blood cells infected with malaria - causing parasites (shown almost completely filling a cell) may avoid imminent destruction if new research pans out.

In the past few years, scientists have proposed several alternatives to deriving human ES cells that would not require destruction of a human embryo (Science, 24 December 2004, p. 2174).

Sommer and his colleagues think that Ubc7p in the cell's cytoplasm binds to Cue1p, forming a complex that both escorts misfolded proteins out of the ER and tags them for destruction.

The patients also showed stabilization and even improvement in measures of insulin production after 12 weeks, suggesting that the therapy might arrest beta cell destruction, the authors say.

The distinction between apoptosis and cell lysis is important in immunology - lysing a virus - infected cell would only release the virions, whereas apoptosis leads to destruction of the virus inside.

«It is morally inconsistent to condemn the destruction of embryos in stem cell research,» Sandel said, «while permitting the destruction of embryos in the IVF clinics.»

In people with Type 2 diabetes, the process appears to not work properly, contributing to the destruction of beta cells.

«Not only did we confirm that the presence of blood in the brain recruits peripheral immune cells to the area, which is sufficient to cause myelin destruction, we also identified fibrinogen as the critical protein driving this process.»

Donn says: «When the enzyme is blocked, ammonia accumulates in the chloroplasts, eventually leading to the destruction of the chloroplasts and plant cells, so that the plants die.»

To solve this mystery, the researchers examined the susceptibility of the variant SRY to destruction by the «proteasome,» a universal molecular machine in the cells of animals and plants that destroys proteins.

Once activated, T cells can home in on a tumor and target it for destruction.

To find out whether increasing cell self - destruction in the lungs could actually decrease cell death — and ultimately prevent lung injury — Bhandari and his research team targeted a regulator protein called RPTOR, which when inhibited, is responsible for inducing autophagy.

Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not controversial because the production of adult stem cells does not require the destruction of an embryo.

If the T - cells miss their target or if they mistakenly order the destruction of a healthy cell, the result will be disease in the form of infection, cancer, allergies or auto - immune conditions.

It plays an important role in cell division, which is controlled by the synchronised destruction of regulatory proteins.

The proteasome plays a key role in the smooth running of a healthy cell, facilitating cell renewal and death — chopping up proteins tagged for destruction into short polypeptides which can then be converted to amino - acids and recycled for use in building new proteins.

Although mitochondria, the tiny capsules that produce energy for the cell, are known to play some role in neurodevelopmental and psychiatric disorders, the contribution of mitochondrial dynamics (mitochondrial trafficking, the regulated fusion and fission, and destruction of mitochondria) has been less clear.

Researchers in the US and Sweden say that the protein can prevent the destruction of brain cells that are lost in Parkinson's, and protect the motor neurons which control muscles.

In addition, the pancreases of the mice receiving ISO - 1 showed much less β - cell destruction than the control group, the team reports online this month in the journal EndocrinologIn addition, the pancreases of the mice receiving ISO - 1 showed much less β - cell destruction than the control group, the team reports online this month in the journal Endocrinologin the journal Endocrinology.

When healthy cells are no longer useful they initiate a chain of events culminating in self destruction.

Type 1 diabetes is a disease caused by the destruction of the insulin - producing cells in the pancreas.

The addition of a small protein named ubiquitin can mark another protein for destruction, relocation in the cell, or it can turn the protein on or off, which can trigger or stop a cellular process, Luo said.

For that purpose, we used a streptozotocin (STZ) model of diabetes, which is widely used in the field to produce destruction of β cells and hyperglycemia (Wilson and Leiter, 1990).

Now, Professor Martin and colleagues have discovered that in response to specific types of cell damage, Parkin can trigger the self - destruction of «injured» nerve cells by switching on a controlled process of «cellular suicide» called apoptosis.

Type 1 diabetes mellitus (T1D) begins with autoimmune destruction of insulin producing cells in the pancreas, usually in children.