Sentences with phrase «cell differentiation»
Cell differentiation refers to the process in which cells change to perform specific functions in the body. This means that cells transform into different types, like a skin cell becoming a nerve cell or a muscle cell. This allows cells to carry out specialized roles, like helping us see, move, or protect our body. Full definition
Stem cell differentiation Stem cell therapy has been growing increasingly popular recently due to it's regenerative effects on chronic problems.
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The localized delivery technique provides spatial control of cell differentiation within the cultures, potentially enabling the creation of complex three - dimensional tissues.
They also are key to cell differentiation in developing organisms, but the mechanisms are not fully understood.
In addition to the visualization of expression profiles during ES cell differentiation, the search engine provides links to analyze the selected genes using many publicly available tools and resources.
In order to better understand how the scientists have come to this conclusion, one needs to get familiar with cell differentiation markers.
These include a reduction in B cell differentiation to plasma cells and a reduced proliferation of T cells.
Both conditions are mutually exclusive and act preventing cell differentiation and promoting cell growth.
I think so because it's a disease that affects cartilage and bone cell differentiation.
Other studies will focus on better understanding the molecular signaling that guides taste cell differentiation and function.
Cell differentiation within a tissue is tightly regulated both in time and space throughout development.
Whether this system can be applied to monitoring and analysis of 3D cell differentiation remains to be studied.
If brown fat is to be increased, the signals / messages for cell differentiation need to be switched from turning into muscle to turning into brown fat.
But scientists have not learned how to do this yet; so, studying stem cell differentiation is an active area of research.
We developed a method to identify all genes that have characteristic expression patterns during ES cell differentiation.
It is already known that various epigenetic mechanisms are associated with cell differentiation.
The pervasive vasculature facilitates stem cell differentiation by enabling delivery of cell growth factors throughout all areas of the tissue.
All the interdisciplinary skills and knowledge he had gathered during his scientific training — which had covered biochemistry, biotechnology, biomaterials, and stem cell biology — put him «in a very advantageous position to address this question» of how to develop nanoparticles that could modulate stem cell differentiation on demand, he says.
In addition to p53, there are other transcriptional activatory mechanisms that are not well understood for the most part and which operate in response to mitogenic stimulation (11, 12), transforming growth factor - β (13, 14, 15), and aberrant oncogenic signals (16, 17) or during a number of cell differentiation processes (18, 19).
Dynamic regulatory network controlling TH17 cell differentiation / N. Yosef *, A.K. Shalek *, J. Gaublomme *, Y. Lee, A. Awasthi, H. Jin, C. Wu, K. Karwacz, S. Xiao, M. Jorgolli, D. Gennert, R. Satija, A. Shakya, D.Y. Lu, J.J. Trombetta, M. Pillai, P.J. Ratcliffe, M.L. Coleman, M. Bix, D. Tantin, H. Park, V.K Kuchroo, A. Regev.
Liew was first to demonstrate roles of nitric oxide within the immune system, both in the process of killing engulfed pathogens and regulating immune cell differentiation.
Verify Th1 cell differentiation by analyzing cytokine expression via flow cytometry or ELISA (optional).
The undifferentiated stem cells were then placed onto a circular - patterned surface that served to physically regulate cell differentiation and growth.
The type of found cell is thought to influence the efficiency of iPS cell differentiation to blood cells, with blood founder cells being best.
The Intestinal Epithelial Cell Differentiation Marker ALPi is Selectively Induced by HDAC Inhibitors in Colon Cancer Cells in a KLF5 - dependent Manner.
Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation towards authentic DARPP - 32 + medium - sized spiny neurons
A protocol describing the use of a recombinant protein - based, animal product - free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies.
The CCP is developing an unbiased reconstruction of genetic and molecular networks that direct cell differentiation in various human cell circuitry systems, such as Th17 immune cells and brain neuronal cell nuclei.
Applications for the rapid electron beam writing of topologically complex 3D nanostructures could include new types of electrode topologies for batteries and fuel cells, vertically - stacked electronic memory, substrates for controlling cell differentiation and tiny electrochemical conversion devices.
IP6 inhibits cancer cell proliferation and increases cancer cell differentiation sometimes reverting back to a normal cell line in vitro.
The CellXVivo ™ Mouse Th1 Cell Differentiation Kit contains optimized reagents for Th1 differentiation from naïve CD4 + cells.
Several more researchers presented their work during the day, including protein synthesis at atomic resolution, bio-imaging opportunities at synchrotrons, multi-dimensional imaging during plant cell differentiation, how to use electron cryomicroscopy for in situ structural biology, and how structured illumination microscopy can offer insights into the regulation of mammalian meiosis.
(A) Schematic of ES cell differentiation toward ADE.
With these findings, Helmholtz Zentrum München scientists have discovered key molecular functions of stem cell differentiation which could be used for beta cell replacement therapy in diabetes.
Surprisingly, Prof. Pfeifer and his team found that the transcription factor also regulates the levels microRNA 155 establishing a tight feed - back loop that works like a toggle switch: When the microRNA is highly expressed brown fat cell differentiation is blocked; conversely, if the transcription factor wins the upper hand, brown fat is produced at an increased level and this in turn boosts fat burning in the body.
Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.
He worked with chemist Olaf Runquist to develop mathematical models of cell differentiation based on colon cancer samples from collaborator Bruce Boman, a professor at the University of Delaware.
First, they used single - cell RNA sequencing to identify the signaling pathways critical for arterial endothelial cell differentiation.
Together, these findings indicate an essential role for Dicer and miRNA processing in white and brown cell differentiation and whole body metabolism that may contribute to the development of HIV - related lipodystrophy.
Kantorow's group focuses on the eye lens and the retina as models for understanding cell differentiation, cell function and disease.
The findings are reported in the article «A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential» published online December 15 in Genes & Development.
Susanna Fraguas, first author of the article, explains that «the study proves that gene egr - 4 is involved in the first phases of brain cell differentiation.