Sentences with phrase «cell differentiation toward»
(A) Schematic of ES cell differentiation toward ADE.
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Using mice deficient in Del - 1, they found that the protein promotes proliferation and differentiation of hematopoetic stem cells, sending more of these progenitor cells down a path toward becoming myeloid cells, such as macrophages and neutrophils, rather than lymphocytes, such as T cells and B cells.
Directed and step-wised differentiation of embryonic stem cells toward neuronal, cardiac and pancreatic lineages
Commitment toward differentiation of pluripotent stem cells is a multi-step process that requires combination of signals.
«What is more, the technique identifies key genes and enriched gene ontology pathways, as well as categories related to stem cell differentiation — and specifically toward osteochondral lineages (that is, related to bone and cartilage tissue growth).»
Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.
Hierarchical clustering organized samples according to differentiation stages, with undifferentiated ES cells and early differentiation states at the left and progressively more differentiated states toward the right.
The next day, the resulting cells were grown in CDM - PVA supplemented with Ly294002 (10 μM; Calbiochem), Activin (100 ng / ml); FGF2 (40 ng / ml; R&D Systems), and BMP4 (10 ng / ml; R&D Systems) to drive their differentiation toward definitive endoderm.
By developing a simple chemically defined culture system permitting efficient differentiation of numerous human iPS cell lines toward cells of a mature hepatic state, we now demonstrate the possibility of modeling groups of diseases of non-neuronal origin whose phenotypes are a consequence of complex protein dysregulation within adult cells.