Sentences with phrase «cell disease shows»

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Studies have shown that their wide array of antioxidants actually inhibit the growth of cancer cells, as well as protecting the body from cardiovascular disease — orange vegetables have been shown to provide the most protection against this disease.

The strict definition of celiac disease — positive antibodies to gliadin, intestinal endomysium, and tissue transglutaminase, together with the presence of HLA - DQ2 or HLA - DQ8 genes and an intestinal biopsy that shows at least 20 - 25 CD3 cells per 100 epithelial cells — will account for about 75 - 80 % of all those sensitive to gluten.

It offers cardio protection, it helps lower bad cholesterol, it may help prevent the progression of multiple sclerosis, it has the ability to regenerate brain cells after a stroke, it has the ability to cross the blood - brain barrier to potentially ward off Alzheimer's disease, apparently it's good at wiping amyloid plaque from the brain (which studies haves linked to Alzheimer's), it may help to prevent certain types of cancer, and studies have shown that it inhibits cancer cell growth and metastases (meaning it keeps cancer from spreading).

If the unborn baby shows signs of Rh hemolytic disease, early labour may need to be induced, so that the mother's antibodies do not destroy too many of the baby's red blood cells.

«Landmark project shows heart disease, rheumatoid arthritis risk raised by genetic changes in blood cells.»

Last year Cuervo collaborated with Sheng Zhang, a professor at The University of Texas Health Science Center at Houston on experiments showing that huntingtin — the Huntington's disease protein — helps the cell's autophagy system identify what it should eliminate.

The idea to specifically study this group of patients was based on groundbreaking research Garon published in the New England Journal of Medicine last year, which found that among patients who received pembrolizumab, those with PD - L1 expression on at least 50 percent of their cancer cells showed the longest survival and disease control.

In this latest advance reported in PNAS, the Wyss team showed that the human gut - on - a-chip's unique ability to co-culture intestinal cells with living microbes from the normal gut microbiome for an extended period of time, up to two weeks, could allow breakthrough insights into how the microbial communities that flourish inside our GI tracts contribute to human health and disease.

Researchers used tissue and blood samples to show that the gammopathy (a precursor to myeloma) in both mice and patients with Gaucher disease is triggered by specific lipids, and that the antibodies made by tumor cells in nearly a third of myeloma patients are directed against such lipids.

We know that they are under stress when they are fighting cancer or other diseases, so I wondered whether anything measureable could be seen if we put them under further stress with UVA light.We found that people with cancer have DNA which is more easily damaged by ultraviolet light than other people, so the test shows the sensitivity to damage of all the DNA — the genome — in a cell.»

This proof - of - principle study shows «for the first time... that human iPS cells can be used to model a diverse range of inherited diseases in adult cells,» the authors wrote in their paper, published online in The Journal of Clinical Investigation August 25.

«Our studies show that mutations in our white blood cell cells, that we acquire as we age, may cause cardiovascular disease.

The researchers have now provided further evidence for this new theory by showing that the abnormal protein coded for this genetic disorder can be transmitted to normal animals by the injection of diseased cells into their brain.

The researchers showed that mice with mutant huntingtin had mitochondria full of VCP, as did nerve cells donated by people with Huntington's disease.

Gene Yeo, a professor of cellular and molecular medicine at UCSD, led the research and showed he could target RNA in living cells, a first step toward treating diseases like muscular dystrophy and neurodegeneration.

This study showed that mtDNA levels are higher in the surviving cholinergic neurons of the brainstem, but with both cell - types that undergo profound degeneration during Parkinson's disease.

Early results show that it causes a drop in levels of certain white blood cells, increasing the possibility of infections, and raises cholesterol, a worrying side effect in a patient population that is already prone to cardiovascular disease.

Research shows that in Parkinson's disease a brainstem region called the pedunculopontine nucleus (PPN) develops changes in DNA found in mitochondria — the batteries of the cell — as they produce and store energy that cells can use.

Boscia, whose cell phone shows an olive tree from his father - in - law's grove as its screen saver, is leading an epic battle against a mountain of bureaucracy and funding cuts to institute an open - air research center to study the disease and eventually find a way to stop it.

The study, published in Nature Communications, shows that membralin regulates the cell's machinery for producing beta - amyloid (or amyloid beta, Aβ), the protein that causes neurons to die in Alzheimer's disease.

«This shows that brain cells are capable of responding even after disease onset, and hints at the potential for reversing Huntington's disease.»

With help from researchers at Duke University, they showed that the gene has a unique pattern of methylation in breast cancer cell lines that might one day help doctors spot the disease.

«Psoriasis treated with compound derived from immune cells: Compound may be effective against other autoimmune diseases, mouse study shows.»

The new research shows that when the atheronals interact with various blood cells, they produce some of the effects known to lead to heart disease, such as causing a malfunction in the cells that line arterial walls.

In Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure: Critical Importance of the Cardiosplenic Axis, Prabhu and colleagues showed that immune cells that are stored in the spleen were intricately involved in the heart failure that follows a heart attack, or infarction, in a mouse - model system.

A clinical trial has shown that patients with a specific molecular subtype of diffuse large B - cell lymphoma (DLBCL) are more likely to respond to the drug ibrutinib (Imbruvica) than patients with another molecular subtype of the disease.

Interdisciplinary research at the University of Pennsylvania is showing how cells interact over long distances within fibrous tissue, like that associated with many diseases of the liver, lungs and other organs.

«Virtual tissue technology reveals new drug target in polycystic kidney disease: Advanced computer simulations show that failures of cell adhesion and inhibition cause two types of kidney cyst formation.»

The study published in Cell Death and Disease showed that aspirin slows down the growth of mesothelioma by blocking the carcinogenic effects of the inflammatory molecule, High - Mobility Group Box 1 (HMGB1).

«Stem cell transplant shows «landmark» promise for treatment of degenerative disc disease.»

Research from Rutgers Cancer Institute of New Jersey shows that the RUNX2 protein, which regulates the transcription of genetic messages responsible for the different functions of cells, may play a role in melanoma cell growth and spread and could serve as a therapeutic target for the disease.

Some of the first evidence for cancer stem cells came from studies of leukemia in the 1990s, which showed that only a small subset of the cancerous blood cells could propagate the disease in mice.

Breast cancer researchers have mapped early genetic alterations in normal - looking cells at various distances from primary tumours to show how changes along the lining of mammary ducts can lead to disease.

«This is the first study to show the actual cell behaviors caused by mutations in genes causally linked to polycystic kidney disease, an important new step in the path towards treatment,» said Dr. Robert L. Bacallao, associate professor of medicine at the IU School of Medicine in Indianapolis.

His laboratory already has shown that by inhibiting calcium channels in T - cells, they were able to prevent T - cell activation in animal models of autoimmune diseases like multiple sclerosis and colitis.

Using a combination of cell - based and mouse models, the researchers showed that the recently - evolved mycobacteria were more virulent, likely to cause more serious disease in patients.

A new study from The Scripps Research Institute (TSRI) is the first to show precisely how a process in nerve cells called the S - nitrosylation (SNO) reaction — which can be caused by aging, pesticides and pollution — may contribute to Parkinson's disease.

Johan Auwerx's team showed that the disease leads to a second cycle of events inside the cells, a series of reactions that exacerbate the disease's damaging effects.

«Rather than innocent bystanders to a malfunctioning immune system, our research shows beta cells are central players in the disease itself.»

In the new study, Lipton and his colleagues used human stem cell and mouse models to show exactly how SNO can trigger cell death in Parkinson's disease.

«We are excited about these findings — they solve a mystery and show how fat synthesis protects cells from dysfunction and disease,» said Robert Farese, Jr., professor of genetics and complex diseases at Harvard Chan School.

In a major breakthrough researchers show it is possible to make dopamine cells from astrocytes, accelerating traditional stem cell procedures and improving disease symptoms

The team found that most of the genetic changes in the original breast tumour were also present in the metastatic tumours, showing that the cancer cells spread late in disease development.

«Advancements in medical research have shown that stem cells can be used to treat certain diseases.

They show that this new formulation reduces the minimal curative dose in a disease model, based on infections in mice, by 100-fold and, most importantly, circumvents drug resistance in a cell line that is resistant as a result of mutations in the transporter that mediates drug uptake.

In additional experiments, the NYU team showed that the TB - transporting dendritic cells had to first pass through the lungs — as would be expected in the natural course of the disease that is passed by someone breathing in infected droplets — before heading to the lymph nodes to elicit a strong immune response.

«Our study shows a whole new route, or bypass mechanism, for triggering the body's adaptive immune response to TB infection, a means by which infected dendritic cells cooperate with uninfected dendritic cells to activate T cells and respond to the infection,» says infectious disease specialist and study senior investigator Joel Ernst, MD, a professor at NYU Langone Medical Center.

«New tumor analysis method identifies high - risk prostate cancer: Cancer cells» genetic pathways show which patients are likely to develop aggressive types of the disease.»

«We discovered that neural progenitor cells show properties that can be associated with the disease and were perfectly suitable for use in large - scale drug screens.

In all species where it has been shown to delay aging and the diseases of aging, it affects the regulation of energy and the ability of cells and the organism to respond to changes in the environment as they age.»