«Over the past few years, City of Hope has seen an increase in patients coming for sickle
cell disease treatment,» Rosenthal said.
Dr. Haywood also serves as a member of the oversight steering committee for the Health Resources and Services Administration's Sickle
Cell Disease Treatment Demonstration Program.
Not exact matches
BlueRock's first two programs are
treatments that could regenerate heart muscle
cells after heart attacks and help replace certain neurons in the brain as they decline in people with Parkinson's
disease.
Unlike some of the promising
treatments that have failed in 2017 that deal with the so - called «amyloid hypothesis» (the
treatments target amyloid beta deposits in the brain that accumulate in people with Alzheimer's
disease), approaches that try to prevent nerve
cells from dying wouldn't have any impact on that buildup.
In March, the U.S. Food and Drug Administration (FDA) approved BLINCYTO for the
treatment of adults and children with B -
cell precursor acute lymphoblastic leukemia in first or second complete remission with minimal residual
disease (MRD) greater than or equal to 0.1 percent.
About Nohla Therapeutics Nohla Therapeutics is a leading developer of off - the shelf
cell therapies for the
treatment of cancer and other critical
diseases.
Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer
cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the
treatment of ocular melanoma, a rare and life - threatening
disease.
New
treatments for everything from cancer to rare genetic
diseases are entering the market all the time, many of which are cutting - edge biologic medicines derived from living
cells.
The biotech specialist said that its updated phase 2 data in a study of its poziotinib candidate
treatment for non-small
cell lung cancer resulted in a preliminary confirmed objective response rate and potential progression - free survival benefit in patients with the EGFR Exon 20 Mutant form of the
disease.
You may not be for stem
cell research, but what if there was a
treatment that utilized stem
cells (that would have been tossed away) that would curb a crippling
disease tormenting your child or loved one?
research; since most of the reports have concentrated on justifying the creation of cloned human embryos for research into and
treatment of neurodegenerative
diseases such as Parkinson's, «stem -
cells» has become synonymous with «embryonic stem -
cells» in the public imagination.
Jiachen Lee, Arooba Ahmed and Jillian Parker, a trio of young scientists from the Half Hollow Hills school district won the $ 100,000 top team award in the prestigious Siemens Competition in Math, Science & Technology for their research into
cell division that could help find
treatments to cancers, viruses and other
diseases.
Stem
cell research and diabetes Stem
cell research is a relatively new area of investigation, believed by many in the scientific and medical communities to have important new potential for the
treatment of many
diseases and conditions particularly those like diabetes, which are characterised by severe damage to certain
cells and tissues..
The Reverend said, however, that while he was struggling to raise the money, the hospital management called to inform him that the Sickle
Cell Foundation of Nigeria had contributed N260, 000 to fund the operation as part of its efforts towards the
treatment of the
disease.
Senator Bernie Sanders (I — VT) has said he believes stem -
cell research «represents an exciting and promising line of research that could provide
treatments and cures for many debilitating
diseases.»
Fat - derived stem
cells can heal nasty wounds associated with Crohn's
disease, and could be the first mass stem
cell treatment to be used in Europe
Trials of
cells made from human embryonic stem
cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem
cells have been used in the
treatment of major lethal
diseases.
Decades after they were discovered, human embryonic stem
cells are being trialled as a
treatment for two major
diseases: heart failure and type 1 diabetes
Although
treatments are available for the
disease, they do not repair the damage to nerve
cells.
As a result, P - gp causes resistance of the
diseased cells to a majority of drugs currently available for the
treatment of cancer, as well as drugs used for
treatment of infectious
diseases like HIV / AIDS.
«Mechanistic finding may help develop
treatment for Ice Bucket Challenge
disease: Study blames a fault in the
cell's machine that cuts and pastes genetic instructions for a deadly motor neuron
disease.»
Yang said the study not only indicated which genes are affected by traumatic brain injury and linked to serious
disease, but also might point to the genes that govern metabolism,
cell communication and inflammation — which might make them the best targets for new
treatments for brain disorders.
A major obstacle to improving
treatment for the 3,470 cases of the
disease expected in the United States this year is the blood - brain barrier, the name given to the tight fit of
cells that make up the blood vessels in the brain.
Stem
cells have long been heralded as a potential
treatment for a range of brain ailments, but research has so far focused on movement disorders such as Parkinson's
disease.
Cancer stem - like
cells are thought to be the root cause of chemotherapy resistance, leading to
treatment failure in patients with advanced
disease and the triggers of tumour recurrence and metastasis (regrowth).
Teams conducting research into
treatment methods for various chronically inflammatory autoimmune
diseases are already using the link between IL - 6 and pathogenic T
cells today.
According to this theory, tumor
cells tend to «forget» the tissue from which they originated as the
disease progresses, acquiring an undifferentiated phenotype associated with heightened aggressiveness and
treatment resistance.
«If we take one of these modified
cells and treat it with a particular drug, if it doesn't produce light anymore, then this means the drug is a potential
treatment for this
disease,» Basu said.
Dr Lee Campbell, Research Projects and Science Communications Manager at Cancer Research Wales, who part - fund the study, commented: «This is an exciting breakthrough as cancer stem
cells are thought to be responsible for the failure of many cancer
treatments and the re-emergence of cancers, often many years after the initial
disease.
Researchers are designing the first clinical trials of stem
cell treatments for fetuses afflicted with rare bone and blood
diseases.
BABY BLUE Using human eye
cells, researchers fashioned an artificial eye surface that could be used to study and test
treatments for eye
diseases.
What's more, the studies suggest how our gut microbes make the immune system turn against nerve
cells — a finding that could lead to
treatments, like drugs based on microbial byproducts, that might improve the course of the
disease.
These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and advances in the use of gene therapy, despite some setbacks; continuing progress in research on stem
cells; the emergence of
treatments for previously untreated
diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.
Specific immune
cells have the ability to produce a healing factor that can promote wound repair in the intestine, a finding that could lead to new, potential therapeutic
treatments for inflammatory bowel
disease (IBD), according to a new research study.
«Only by understanding the complexities of what happens in specific
cell - types found in specific areas of the brain during this
disease can targeted
treatments for Parkinson's
disease be produced.»
«The implications are that understanding these
cells, the factors and the pathways may offer us the ability to modulate this pathway during inflammatory bowel
disease, which could lead to
treatment and promote healing and recovery from inflammatory bowel
disease,» Denning said.
The finding identifies how vulnerable
cell groups react and respond differently to the accumulation of mitochondrial DNA damage seen in the
disease, highlighting the need for
cell - specific
treatments.
The studies not only point to the future possibility of specific microRNAs as a
treatment for colorectal cancer, but also to the importance of external metabolic events conducted outside the cancer
cell in the progression of the
disease — factors that could someday be targeted to help slow metastasis, or even block it entirely.
«The ability to control autoimmunity by autologous HSCT [hematopoietic stem
cell transplantation] has been demonstrated in other
treatment - refractory autoimmune conditions, including neurologic
diseases.
Researchers targeting colorectal cancer stem
cells — the root cause of
disease, resistance to
treatment and relapse — have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection.
New technology that transforms a
cell phone into a powerful, mobile microscope could significantly improve malaria diagnoses and
treatment in developing countries that often lack the resources to address the life - threatening
disease, says a Texas A&M University biomedical engineer who has created the tool.
«How to reprogram
cells in our immune system: The discovery could improve
treatments for autoimmune
diseases and cancer.»
Despite a lack of rigorous clinical trials to test safety or efficacy, a ban of the
treatment by health authorities, and a lack of peer review by the scientific community, the privately funded Stamina Foundation has been using cultured mesenchymal stem
cells that have been exposed to putative conditions that favour neuronal differentiation to treat different
diseases in severely or terminally ill patients.
«Stem
cells may offer unprecedented opportunities to develop
treatments for many
diseases with unmet medical needs.
In addition to providing insights regarding selection of
treatment, this blood test may also prove helpful in assessing the presence of residual
disease, recurrence, or relapse and detection of therapy - resistant cancer
cells more quickly than conventional tissue - based methods.
They hope to go still further and turn the stem
cells into
treatments for previously untreatable
diseases.
By manipulating the function of certain immune
cells, called T
cells, researchers could help restore the system's balance and create new
treatments to target these
diseases.
«We hope that these
cells can eventually lead to new
treatments for glaucoma and other forms of optic nerve
disease.»
Dr Leonardo Guasti added: «It represents an entirely new concept for the study of the adrenal gland as the ability to generate donor - specific and functional adrenal - like
cells will facilitate the next generation of
cell - based
treatments for adrenal insufficiency, the modelling of adrenal specific
diseases, and the testing of personalised interventions on
cells derived from patients.»
Certain conditions affect one sex more than the other, he notes, so «if the genetics of a
cell affects the progress of a
disease, it might suggest specific causes or
treatments for
disease.»