Sentences with phrase «cell disease use»

Recently, scientists have uncovered many of the molecules in the pathway that control the switch from fetal to adult hemoglobin, opening the door to new therapies; if you could prevent the switch from happening, or reverse it, and let people with sickle cell disease use fetal hemoglobin for life, that should reduce symptoms.

Not exact matches

Venter reiterated this sentiment: «Using the combined power of our core areas of expertise — genomics, informatics, and stem cell therapies, we are tackling one of the greatest medical / scientific and societal challenges — aging and aging related diseases,» he said in a statement.

CRISPR gene - editing has already been vaunted as a tool that could eventually be used to tackle everything from HIV / AIDS to sickle cell disease to a variety of other disorders.

«Using the combined power of our core areas of expertise — genomics, informatics, and stem cell therapies, we are tackling one of the greatest medical / scientific and societal challenges — aging and aging related diseases,» said Dr. Venter.

Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human biological decline.

Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the treatment of ocular melanoma, a rare and life - threatening disease.

Since its foundation in 2005, the NYSCF has become a leader in using stem cell research and technology to find cures for a range of diseases, from heart disease and diabetes to Alzheimer's and Parkinson's.

Stem cells can transform into any other human cells, so they have immense potential for generating all sorts of adult cells and thus can be used in research concerning human degenerative (and other) diseases.

Where is the clear line in a progression from (1) using animal insulin to treat diabetes, to (2) using gene remodeling techniques to grow insulin in a host bacterium that will reproduce rapidly and from which a plentiful supply of insulin can be harvested, to (3) genetic surgery to replace the defective gene in a person diagnosed as diabetic, to (4) genetic surgery immediately after fertilization in order to replace the defective gene and alter the germ cells which would otherwise have transmitted the disease to one's offspring?

Though there have been many strides made towards ending the HIV / AIDS epidemic, such as the recent breakthrough of scientists using gene editing to remove HIV from the genome of T - cells, there is still much work to be done with over 1.2 million in the United States living with the disease.

Australian scientists have discovered that group of immune cells, once considered junk, are actually a secret weapon the body uses to fight disease.

A review of the athlete's past medical history should include a history of medication and supplement use, cardiac disease, sickle cell trait, and previous heat illness.

So hold on tight, I'm gonna share EVERYTHING I've learned so far about cord blood with you... starting with this enlightening link on the general benefits... including the fact that «To date it can treat more than 80 diseases using Haematopoietic Stem Cell (HSC) transplants, including leukemia, sickle cell anemia, and metabolic disorders.&raCell (HSC) transplants, including leukemia, sickle cell anemia, and metabolic disorders.&racell anemia, and metabolic disorders.»

Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

Cord blood stem cells can be used to treat dozens of diseases and are being tested in FDA - regulated clinical trials to help people with autism, brain injury, and other conditions.

«There are perfectly ethical ways of obtaining stem cells to cure disease, which do not involve embryo destruction, so no matter what moral value one places on the human embryo, we do not need to use it.»

Instead, after several days, researchers harvest embryonic stem cells, which theoretically can develop into any type of cell and, according to many researchers, may someday be used to treat neurodegenerative diseases or other conditions.

It is possible that spider silk could also be used in future for other neurological diseases where cell transplantation plays a role.

Altering DNA in germline cells — embryos, eggs, and sperm, or cells that give rise to them — may be used to cure genetic diseases for future generations, provided it is done only to correct disease or disability, not to enhance people's health or abilities, a report issued February 14 by the National Academies of Sciences and Medicine recommends.

«If we could use gene editing to remove the sequences in an embryo that cause sickle cell disease or cystic fibrosis, I would say not only that we may do so, but in the case of such severe diseases, we have a moral obligation to do so.»

Cells in umbilical cord blood are already being used to treat certain diseases, including... Read More

On Thursday, the United Nations» member states will consider two resolutions: One resolution would ban all human cloning methods, including efforts to use cloned embryonic stem cells to try and generate healthy tissues, or to treat degenerative diseases such as Parkinson's.

A related paper, involving Svendsen, his colleague Gad Vatine, PhD, and a team from University of California, Irvine, published the same day in the journal Cell Reports, used a similar approach to study Huntington's disease.

Furthermore, by making use of embryonic stem cells and in vitro differentiation, SIF - seq can be used to assess enhancer activity in a wide variety of disease - relevant cell types.»

Adds Pennacchio, «The range of biologically or disease - relevant enhancers that SIF - seq can be used to identify is limited only by currently available stem cell differentiation methods.

Fat - derived stem cells can heal nasty wounds associated with Crohn's disease, and could be the first mass stem cell treatment to be used in Europe

In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in general.

Physicians are using smart phones to diagnose diseases, check blood cell counts and identify pathogens in drinking water

Because they can differentiate into almost any cell type in the body, stem cells have the potential to be used to create healthy cells to treat a number of diseases.

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

Both diseases result from the death of retinal cells, a process that Lanza suspects can be slowed or even halted using stem - cell - derived replacements.

It also sought to match epigenetic changes and genetic differences to the physical characteristics of each cell type and use this knowledge to understand how these can lead to blood disorders, cancer and other complex diseases.

Scientists use cell reprogramming techniques to produce cells in the lab so that they can study diseases.

Alfano states «Resonant Raman using the laser pointer 532 nm has become an e?cient tool for investigating molecular components in tissues and cells, providing more detailed information and a way to detect diseases like skin cancer, brain cancer, or atherosclerosis — in mere seconds.»

Exposed to both air and fluid, the cells might also be used to model the lungs and test drugs for lung disease.

The researchers are beginning to use their model to test whether Zika virus, and other pathogens associated with congenital disease, can infect placental cells and / or cross the placental barrier.

The advantages of MFCs may allow widespread use of diagnostic procedures that are currently too expensive to implement (e.g., prescreening for cancer) while the new capabilities may dramatically improve our ability to understand complex diseases such as cancer (e.g., through single - cell analysis).

«Many diseases, especially complex diseases, involve multiple genes, and this system could be used therapeutically to target and activate multiple genes together and rescue these disease phenotypes,» says Albert Cheng, a graduate student in the Jaenisch lab and co-author of the Cell Research paper.

The survey, described today in a Policy Forum published by Science, randomly presented people with different vignettes that described genome editing being used in germline or somatic cells to either treat disease or enhance a human with, say, a gene linked to higher IQ or eye color.

«Cultural revolution in the study of the gut microbiome: Human gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.»

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

Still, researchers are intrigued by the possibility that cells may use these clearance mechanisms to propagate misfolded proteins throughout the brain — in which case targeting the mechanisms could conceivably slow disease progression.

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania.

As a result, P - gp causes resistance of the diseased cells to a majority of drugs currently available for the treatment of cancer, as well as drugs used for treatment of infectious diseases like HIV / AIDS.

The Porteus team started with human stem cells from the blood of patients with sickle cell disease, corrected the gene mutation using CRISPR and then concentrated the human stem cells so that 90 percent carried the corrected sickle cell gene.

Kopelman plans to continue using his device to probe cells for clues about what happens when diseases or toxins injure them.

Researchers used tissue and blood samples to show that the gammopathy (a precursor to myeloma) in both mice and patients with Gaucher disease is triggered by specific lipids, and that the antibodies made by tumor cells in nearly a third of myeloma patients are directed against such lipids.

• Stem Cells Stem cells made from adult tissues can be used to investigate how different drugs could help alleviate certain diseCells Stem cells made from adult tissues can be used to investigate how different drugs could help alleviate certain disecells made from adult tissues can be used to investigate how different drugs could help alleviate certain diseases.