Sentences with phrase «cell disorder as»

My Baby Girl now has a red blood cell disorder as a result of having taken Raglan.

Not exact matches

CRISPR gene - editing has already been vaunted as a tool that could eventually be used to tackle everything from HIV / AIDS to sickle cell disease to a variety of other disorders.

For example, if you or your baby's father were previously screened for genetic disorders (such as sickle cell trait, cystic fibrosis, or Tay Sachs), those tests will not need to be repeated because the results would be the same.

In order for your child to inherit your recessive genetic disorder, such as cystic fibroisis, sickle cell disease, fragile X syndrome or Tay - Sachs, both the male and the female partner have to pass on their copy of the mutated gene.

A 2013 study by Cheryl Watson at The University of Texas Medical Branch at Galveston found that even picomolar concentrations (less than one part per trillion) of BPS can disrupt a cell's normal functioning, which could potentially lead to metabolic disorders such as diabetes and obesity, asthma, birth defects or even cancer.

In the new study, the scientists expressed surprise that the early abnormal growth of brain cells they observed in the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autism.

Cord blood transplants are also accepted as treatment for thalassemia and sickle cell anemia, inherited blood disorders that are prevalent in certain ethnic groups.

If left to accumulate, this «junk» can overwhelm nerve cells» quality control systems, triggering incurable brain disorders such as Alzheimer's, Parkinson's and Huntington's.

As a result, tau accumulates inside cells to form the infamous clumps that are considered hallmark pathology in neurodegenerative disorders such as Alzheimer's and progressive supranuclear palsAs a result, tau accumulates inside cells to form the infamous clumps that are considered hallmark pathology in neurodegenerative disorders such as Alzheimer's and progressive supranuclear palsas Alzheimer's and progressive supranuclear palsy.

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

Strategies that boost the cell's quality control programs, rather than disarm specific pathologic proteins, have looked promising in lab animals that serve as models for human neurodegenerative disorders including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

Stem cells have long been heralded as a potential treatment for a range of brain ailments, but research has so far focused on movement disorders such as Parkinson's disease.

These findings also have implications for treatment of cancer and other disorders, such as obesity, in which M2 macrophage cells play a regulatory role in tumor growth and fat deposition.

Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and ACell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and Acell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and Acell anemia, thalassemia, and AIDS.

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.

To acquire new insights into the biology and possible therapy of these tumors, Feigin et al. looked for aberrant expression of G protein — coupled receptors, cell signaling proteins that have been successfully targeted for treatment of other disorders such as depression.

This new insight into how chromosomes are disassembled and reassembled during cell division will allow researchers to begin answering basic questions about epigenetic inheritance, as well as human disease such as chromosome disorders and cancer.

Free radicals attack weak carbon - hydrogen bonds and are a major source of the kind of oxidative cell damage that can occur in conditions such as coronary artery disease, neurological disorders and retinal ailments.

And to study many developmental disorders, such as fragile X syndrome, researchers would be well served to be able to study a stem cell line that contained the relevant mutations.

However, he added, the patient - derived iPSCs are highly useful as a model cell system for investigating blood disorders.

For some disorders, donor cells may work just as well as (or better than) a person's own cells.

The discovery of a new mechanism that controls the way nerve cells in the brain communicate with each other to regulate our learning and long - term memory could have major benefits to understanding how the brain works and what goes wrong in neurodegenerative disorders such as epilepsy and dementia.

As they continue to explore what disordered proteins do inside the cell, researchers are also pursuing basic questions about how disordered proteins work.

When the body has an imbalanced number of Treg cells, its immune tolerance can fail and experience autoimmune disorders such as arthritis.

Dysfunction of these cells, as may occur in disease, is linked to neurodevelopmental disorders and neurodegenerative conditions.

Microglial cells may malfunction in neurodegenerative disorders such as Alzheimer's disease, and there is some evidence that they worsen the damage caused by a stroke.

In a 2006 study published in Cell, Vidal and Huda Zoghbi, a neurobiologist at Baylor College of Medicine in Houston, Texas, teamed up to show previously unsuspected interactions among the proteins produced by mutated genes in several of the movement disorders known as ataxias.

The off - target antibodies and overdose usage of antibodies can cause side effects such as an autoimmune disorder, which can damage normal tissue cells.»

The primary cause of anemia is iron deficiency, but it can co-occur with other conditions, such as malaria and genetic disorders like sickle cell.

An inherited disorder that results in the progressive breakdown of nerve cells in the brain, Huntington's leads people to lose control of their speech and movement, as well as to cognitive decline.

Developing safe and effective therapies for conditions such as peripheral nerve disorders requires the ability to take investigations from cells in a petri dish to patients in a clinic.

In a study of mice, they found that they could correct the mutated gene that causes a rare liver disorder, in 6 percent of liver cells — enough to cure the mice of the disease, known as tyrosinemia.

Dr. Monteggia's lab focuses on the molecular and cellular bases of neural plasticity, the fundamental property of nerve cells to alter their communication, as they pertains to neuropsychiatric disorders, as well as understanding the mechanisms underlying antidepressant efficacy.

No one denies that some groups are more vulnerable than others to certain disorders, such as sickle - cell anemia, and thus knowing someone's race or ethnicity can be as pertinent to diagnosis as knowing their sex.

Somatic brain mutations, affecting just pockets of cells, can be harmful, and have been suggested as a possible cause of neurodevelopmental disorders such as autism, epilepsy or intellectual disability (see this review article for further background).

One single stem cell from the bone marrow is not going to be able to treat disorders as different as Alzheimer's disease and rheumatoid arthritis,» he says.

British newspapers reported this weekend that Ian Wilmut, the University of Edinburgh biologist who led the team that in 1997 cloned Dolly the sheep, is getting out of the cloning business in light of the new findings, which seem to offer researchers a likely new source of stem cell lines for basic research that could one day lead to new treatments and perhaps cures for spinal injuries, diabetes and debilitating disorders such as multiple sclerosis and Parkinson's disease.

On the flipside, targeting this growth factor or BCL - 2 could reduce NK cell numbers and offer potential therapies for immune disorders such as some types of autoimmune diseases, sepsis or graft versus host disease, a side effect of bone marrow transplants.

A preclinical study in mice published by Cell Press January 16th in the journal Cell reveals that drugs known as histone deacetylase inhibitors (HDACis) can enhance the brain's ability to permanently replace old traumatic memories with new memories, opening promising avenues for the treatment of posttraumatic stress disorder (PTSD) and other anxiety disorders.

Other plans include using CRISPR to reverse blood disorders, such as sickle cell anemia and beta thalassemia, caused by mutations in the hemoglobin gene.

National Institutes of Health Director Francis Collins delivered an upbeat assessment of what lies in store for the world's largest supporter of biomedical research, projecting advances in battling genetic disorders such as sickle cell disease and the development of an atlas of human cells to...

Gene editing techniques have the potential to treat blood disorders that run in families, such as thalassemia and sickle cell anemia, but their application has been largely limited to cells in a laboratory and not living animals.

These findings may help explain why some people with mutations in certain ribosomal protein genes develop conditions such as Diamond - Blackfan anemia — a blood disorder in which the bone marrow doesn't make enough red blood cells — but don't have problems in other body tissues, Ware says.

Rather than artificially triggering cancer by engineering genetic mutations, this model more closely mimics human liver cancer in that tumors develop as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic disorder that causes liver damage, fibrosis and numerous cell mutations.

Certain light - sensitive molecules also can be used to inhibit the activity of brain cells, a finding that has implication for disorders such as epilepsy.

Along with his colleagues, Shaqfeh has now created the first simplified computer model of the process that forms that layer — a model that could help to improve the design of artificial platelets and medical treatments for trauma injuries and for blood disorders such as sickle cell anemia and malaria.

Meanwhile, neurobiologist Ricardo Dolmetsch, an autism researcher at Stanford University in California, says, «The consensus in the autism research community, as well as in the stem - cell community, is that there is no scientifically valid reason for using stem cells to treat autism spectrum disorders».

They are also interested in exploring the potential role of these cells in models of neurodegenerative movement disorders such as amyloid lateral sclerosis.

Using both patient samples and mouse models, they then linked these bacteria to cells that help regulate inflammation, known as Th17 cells, in people with autoimmune disorders.

The research, published in Nature Cell Biology today, means that these disorders, known as ciliopathies, can be diagnosed more quickly and could lead to new treatments for patients.