Sentences with phrase «cell donor from»

Not exact matches

At present artificial red blood cells are produced from donor blood and the method isn't efficient because limited quantities of RBC can be produced.

For instance, the egg - cell cytoplasm strips off all of the many epigenetic factors which differentiate a genetically restricted donor skin cell from a totipotent zygote.

In November the Lancet published the results of an international research project whereby a Colombian lady received a new trachea (windpipe) which had been grown from a donor trachea (as it were, a «scaffold») repopulated with stem cells, for the very first time, from the patient's own body.

The cell nuclei are removed from both sets of embryonic cells, as shown in the diagram, the donor's nuclei and the remains of the parents» embryo are destroyed and the parents» nuclei are then inserted into the donor or «host» embryo, still containing its healthy mitochondria.

We extract the DNA from the cheek cells and use it to create a series of 32 numbers that are unique to that donor.

Guess what: most of us use the internet in some way, whether on a computer or a cell phone, and online tools from advertising to social media outreach can be great ways to connect with donors, volunteers and voters.

Both involve a technique called nuclear transplantation — replacing the nucleus of a donor's egg with the DNA from an adult cell.

Because the Augment technique uses mitochondria from the mother's ovarian stem cells rather than a donor, there is no three - parent ethical quagmire to wade through.

One donor gave eight eggs, of which four yielded colonies of hESCs, suggesting several colonies could be made from each set of donated eggs (Cell, DOI: 10.1016 / j.cell.2013.05.006).

Healthy, non-cancerous stem cells from a donor can then repopulate the blood.

Creating a whole set of miniature new livers might take as little as obtaining liver cells from healthy donors and placing them inside the lymph nodes of patients suffering from liver disease.

The team also tested nanoparticle absorption for other kinds of human cells, including fibroblasts from donors of older ages and found significant differences.

To make the rat kidneys, Ott and his colleagues took kidneys from healthy «donor» rats and used a chemical solution to wash away the native cells, leaving behind the organ's scaffold.

The neural progenitor cells used were derived from iPSCs (induced pluripotent stem cells), which were in turn derived from donor skin cells.

«We concluded that stem cells used in cardiac therapy should be drawn from healthy donors or be better genetically engineered for the patient.»

The researchers added human bone marrow stem cells from a non-diabetic donor to a bone fracture in laboratory pre-clinical studies.

Although red cells from donors have a typical shelf life of 42 days, they are a mix of older and newer cells, which means a number of them may not last long in the body.

They both had standard chemotherapy to kill their native blood cells before undergoing a bone - marrow transplant from a donor to repopulate their blood.

Research involving the derivation and use of stem cells from adult tissues is permissible, subject to the informed consent of the tissue donor.

In obtaining consent from donors of cells, gametes, tissues, foetal materials, and embryos, the information provided to the donors must be comprehensive, and there must not be any inducements, coercion, or undue influence.

Research involving the derivation and use of stem cells from cadaveric foetal tissues is permissible, subject to the informed consent of the tissue donor.

For the derivation and use of ES cells, there must be informed consent from the donors of surplus human embryos, gametes, or cells.

Only stem cells from healthy donors or genetically engineered cells should be used in treating cardiac conditions.»

In 2015, she and colleagues in Church's lab used CRISPR to eliminate from pig cells 62 genes so potentially dangerous their very existence nixed previous efforts to turn pigs into organ donors.

One company, Melbourne, Australia — based Mesoblast, is already in late - stage clinical trials, treating hundreds of chronic heart failure patients with stem cell precursors drawn from healthy donors» hip bones.

Six months later, blood cells from both the donor and host were still circulating around the body.

If researchers could reduce the loss of cells, they could one day treat two or even three times as many patients from the limited number of cadaver donors available, García noted.

For these clones, the donor cells were fibroblasts taken from fetuses.

Now cells from two one - year - old babies born as a result of this treatment have indeed turned out to have a little extra DNA from a donor mother, as well as that from their own parents.

In addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin production.

«Islet cells are very precious because we get so few from each donor.

However, in the past decade scientists realized that exosomes play important roles in many biological functions through capsuling and delivering molecular messages in the form of nucleic acids and proteins from the donor cells to affect the functions of nearby or distant cells.

In humans, a comparison of bone marrow from 14 normal bone marrow donors, 35 multiple myeloma patients and 11 patients with a noncancerous condition called monoclonal gammopathy of undetermined significance (MGUS) showed that Runx2 levels were significantly higher in the multiple myeloma cells.

They want to explore whether mitochondria from younger donors» cells may stimulate the older eggs» ability to be fertilized and develop normally.

These donor cells are relatively unspecialized cells taken from fetuses.

She began wondering whether donor cells from the mother might be the most likely to get accepted.

In theory, new embryos then could be created by combining converted egg or sperm cells with natural ones, or by combining eggs with sperm cells derived from different donor animals.

They received either a saline placebo or plasma — blood from which the red cells have been removed — from blood donors aged 18 — 30.

Increasing the expression of one of the proteins, SIX3, in the insulin - producing cells isolated from younger donors enhanced their ability to respond efficiently to rising glucose levels.

«We have just allocated $ 271 million in funds, which leveraged over $ 500 million from donors and the institutions» own reserves to build 12 stem cell institutes in California; these are really large institutes that will accommodate a very large number of scientists,» says Trounson, an Australian native who pioneered in vitro fertilization in the 1980s and relocated to California to head up the CIRM in December 2007.

To test their hypothesis, the researchers harvested dermal papillae from seven human donors and cloned the cells in tissue culture; no additional growth factors were added to the cultures.

«This method offers the possibility of inducing large numbers of hair follicles or rejuvenating existing hair follicles, starting with cells grown from just a few hundred donor hairs.

We prepared 59 sets of virus - specific cells from different donors following this procedure.»

To prepare the virus - specific cells, «we take blood from healthy donors who have already been exposed to these viruses and who we have confirmed have immune cells that can fight the infections,» Tzannou said.

Dr Leonardo Guasti added: «It represents an entirely new concept for the study of the adrenal gland as the ability to generate donor - specific and functional adrenal - like cells will facilitate the next generation of cell - based treatments for adrenal insufficiency, the modelling of adrenal specific diseases, and the testing of personalised interventions on cells derived from patients.»

McCain would ban scientists from using donor eggs to create disease - specific stem cell lines or chimeric animals to see how human stem cells behave during development.

Regulatory changes, under which the Japanese government allowed the distribution of iPS cells for clinical use, also prompted researchers to switch the study to a more efficient process of using cells from third - party donors instead of using a patient's own cells.

When spleen CD4 + T - cells were transferred from heart - attack donor mice to naïve recipient mice, they induced long - term left ventricle dysfunction, fibrosis and enlargement, hallmarks of heart failure.

Scientists had suggested that it might one day be possible to circumvent the shortage of donor eggs from adult women by developing ways of maturing undeveloped egg cells from a fetus in the laboratory (This Week, 15 January).

He did, however, publish a paper last year documenting a study in which he infused three cancer patients with white blood cells from young donors who had been injected with G - CSF.