Once Woolly Mammoth - like traits appear sufficiently in stem cell derived tissues, the Church Lab can begin experiments to generate embryos, possibly through stem
cell embryogenesis.
Advanced reproductive techniques such as artificial insemination, culturing of primordial germ cells for germ - line transmission, stem
cell embryogenesis, and cloning offer an array of new ways to expand and even infuse lost and new genetic variability into at - risk wildlife populations.
Not exact matches
Davies and Lineweaver suggest that genes active in
embryogenesis and switched off later may be reactivated because of damage, causing the accelerated
cell division of these rogue cancer
cells.
Baylin says certain genes that control
cell growth get turned down periodically during certain stages of life, including
embryogenesis, when organisms are growing and developing rapidly.
Although this is a normal process in
embryogenesis to build new tissues, when it occurs in cancer
cells it generates metastasis.
Recent work has also shown that over - or underexpression of certain genes in Arabidopsis plants can prompt
embryogenesis in otherwise normal - looking leaf
cells.
In order to elucidate the significance of early epigenetic modifications on the development of neural
cells during
embryogenesis in the mouse, Götz and her colleagues specifically inactivated the gene Uhrf1.
Each colored circle in the image shows one of the embryo's
cells, and the corresponding tail indicates that
cell's movement over a short time interval during early
embryogenesis (at around 3 hours post-fertilization).
Tschinkel believes that an ant colony grows just as a single organism does, by rules that guide interactions among its
cells and between it and its environment, a process called
embryogenesis.
«Our focus here has been on early heart development, but the basic principles of patterning of human pluripotent stem
cells, and subsequently differentiating them, can be readily expanded into a broad range of tissues for understanding
embryogenesis and tissue morphogenesis,» said Healy.
We applied this to systems spanning four orders of magnitude in space and time, including the diffusion of single transcription factor molecules in stem
cell spheroids, the dynamic instability of mitotic microtubules, the immunological synapse, neutrophil motility in a 3D matrix, and
embryogenesis in Caenorhabditis elegans and Drosophila melanogaster.
«Our focus here has been on early heart development, but the basic principles of patterning of human pluripotent stem
cells, and subsequently differentiating them, can be readily expanded into a broad range of tissues for understanding
embryogenesis and tissue morphogenesis,» said Dr. Healy.
This relationship is perhaps most striking during the first stages of
embryogenesis, when
cells change in size and shape several fold in the absence of growth.
Stelzer concentrates his efforts on applications and further developments of advanced light microscopies in the modern life sciences, working on various aspects and applications of three - dimensional
cell biology, lateral root development in Arabidopsis thaliana and the
embryogenesis of, amongst other insects, Tribolium castaneum.
A mammary stem
cell population identified and characterized in late
embryogenesis reveals similarities to human breast cancer
Our recent analysis of SAC signaling in C. elegans revealed that there is a gradual increase in SAC strength during early
embryogenesis, as
cells become smaller and smaller (1).
Albeit still in rudimentary form - since it can't further develop into a healthy fetus because of the absence of endoderm
cells - the newly constructed artificial embryo leads scientists closer to understanding how
embryogenesis works.
The gonidial
cells undergo
embryogenesis to produce new juvenile spheroids that hatch from their mother spheroid, whereas the somatic
cells that are left behind eventually senesce and die.
In heart development, prior to birth (
embryogenesis) heart
cells (cardiomyocytes) proliferate and develop into different parts of the heart.
We estimate that approximately three base substitution mutations occur per
cell per
cell - doubling event in early human
embryogenesis and these are mainly attributable to two known mutational signatures.
These genes have been also implicated in the gastrulation phase of
embryogenesis [55] indicating that «Time Series» clusters provide a comprehensive collection of genes expressed at specific stages of ES
cell differentiation and early embryonic development.
In mammals, inductive signaling early in
embryogenesis creates a small number of primordial germ
cells (PGCs).
It is expressed in tissue progenitor
cells and plays a role in
embryogenesis.
Our studies may also serve to enhance competence for somatic
embryogenesis in recalcitrant genotypes / explants through the manipulation of overall chromatin organisation in target
cells using various chromatin - related drugs.
Such
cells provide a better model of early human
embryogenesis than conventional ESCs in later stages of development.