Sentences with phrase «cell engineering at»

«This paper is a great example of how chemistry can help make step changes in biology,» says Matthew Dalby, a professor of cell engineering at the University of Glasgow and co-senior author on the study with Ulijn.

Not exact matches

Brendan Frey, CEO of Deep Genomics and a biomedical engineering professor at the University of Toronto, says his research team trained its system to analyze individual cells to draw conclusions about the entire cellular system and, ultimately, make a diagnosis.

Technology by Cellectis allows cellular engineering, and a human trial of the company's work in editing blood cells will be presented at the upcoming American Society of Hematology.

February 2, 2017 By Ann Perry http://mbd.utoronto.ca/ When Arif Aziz learned last fall about a new independent study project that was bringing together MBA candidates and PhD students in health sciences and engineering to map the global market for stem cell therapies, he jumped at the opportunity.

By turning cell biology into an engineering discipline, CCC aims to develop new chemicals and materials for medical and consumer applications, while at the same time training a more diverse research and manufacturing workforce.

Carlos Filipe, a chemical engineer at McMaster University in Hamilton, Canada, and colleagues have developed a new kind of flexible film that's coated in molecules that glow when they touch E. coli cells.

«Look at all the issues — climate change, stem cell research, general environmental issues, health care, energy — that all have a fundamental scientific or engineering basis.

The design and formation of an atomic - scale bridge between different materials will lead to new and improved physical properties, opening the path to new information technology and energy science applications amongst a myriad of science and engineering possibilities — for example, atoms could move faster at the interface between the materials, enabling better batteries and fuel cells.

«This research represents an important step toward the goal of being able to better treat thyroid diseases and being able to permanently rescue thyroid function through the transplantation of a patient's own engineered pluripotent stem cells,» explained co-corresponding author Anthony N. Hollenberg, MD, Chief of the Division of Endocrinology, Diabetes and Metabolism at BIDMC and Professor of Medicine at Harvard Medical School.

By using engineered zinc - finger nucleases (ZFNs) designed to target an integrated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a single injection of DNA or messenger RNA encoding ZFNs into the one - cell rat embryo leads to a high frequency of animals carrying 25 to 100 % disruption at the target locus.

In an amazing feat of tissue engineering, Anthony Atala and his research team at the Children's Hospital in Boston are creating new organs in the laboratory using patients» own cells and by employing the same technology used to clone Dolly the sheep.

To hunt for drugs that target these cells, Piyush Gupta, a molecular biologist at the Broad Institute at the Massachusetts Institute of Technology, and colleagues genetically engineered ordinary human cells so that they acquired some of the properties of cancer stem cells, including being impervious to chemotherapy.

Letian Dou, a chemical engineer at Purdue University, and colleagues were only able to form these light - harvesting crystals in their solar cells by cranking the heat to 105 ° Celsius, much hotter than your average sun - blasted window.

Jürgen Hauer, a co-author of the report and a junior research group leader at the Photonics Institute of the Vienna University of Technology, explained that natural systems have evolved to use light efficiently, but there are some caveats before engineers can design a solar cell that works as effectively as a leaf.

To solve this problem, Smadar Cohen, a tissue engineer at Ben - Gurion University of the Negev in Beersheba, Israel, and colleagues seeded rat cardiac cells onto scaffolds which they transplanted into the omentums of eight rats.

«By treating with chemotherapy, we're driving cells through a transition state and creating vulnerabilities,» said first author Aaron Goldman, PhD, a postdoctoral fellow in biomedical engineering at BWH.

Dr. Zubair is working with engineers at the University of Colorado who are building the specialized cell bioreactor that will be taken to the ISS within a year for the experiment.

The Bush administration and automakers are touting fuel - cell vehicles as a nonpolluting technology, but engineers at the Laboratory for Energy and the Environment at MIT say the nonpolluting claim is not necessarily true.

So far, researchers have mostly turned on genes with CRISPRa in cells growing in lab dishes, says Charles Gersbach, a biomedical engineer at Duke University not involved in the new study.

Carbon capture is an obvious extended use for fuel cells, said Tony Leo, vice president of application engineering and advanced technology development at FuelCell Energy.

One of the 12 audience members was Ben Chao, a chemical engineer with a Ph.D. — not at all qualified to make a judgment on Scott's abilities in the area of «Approaches to Developing Serum - Free Media Formulations for Mammalian Cells in Culture.»

«We are the first to engineer a whole liver organ with human cells,» says Shay Soker, a co-developer of the livers at Wake Forest University Baptist Medical Center in North Carolina.

Current research is looking at why inhibiting certain molecules, such as mouse protein Stat3, promote muscle regeneration in mice and how to engineer orthopedic implants from stem cells to replace damaged cartilage and bone, but the results of that effort aren't expected to be necessarily aimed at the old.

«One of the broader goals of our research is to make regenerative treatments more accessible and clinically relevant by developing easy, efficient and cost - effective ways to engineer human cells and tissues,» said Shyni Varghese, a bioengineering professor at UC San Diego and senior author of the study.

Researchers at the University of Southampton have engineered cells with a «built - in genetic circuit» that produces a molecule that inhibits the ability of tumors to survive and grow in their low oxygen environment.

Currently a professor of materials science and engineering at Lehigh University in Pennsylvania, he says it was his job to «examine how radiation in space affects solar cells and semiconductors.»

Likewise, at BD Biosciences in San Jose, California, jobs include opportunities for scientists in many different disciplines (biochemistry, molecular biology, cell biology, immunology, chemistry), as well as hardware and software engineering of all descriptions.

«The EPF2 peptide acts like a morphogen which alters stem cell character in the epidermis of growing leaves and blocks the formation of stomata at elevated CO2,» explains Engineer.

Previously, researchers have produced hydrogen gas in microbial - powered, batterylike fuel cells, but only when they supplemented the energy produced by the bacteria with electrical energy from external sources — such as that obtained from renewable sources or burning fossil fuels, says Bruce Logan, an environmental engineer at Pennsylvania State University, University Park.

The cells are held within a millimeter - scale table - top microbioreactor, containing a microfluidic chip, which was originally developed by Rajeev Ram, a professor of electrical engineering at MIT, and his team, and then commercialized by Kevin Lee — an MIT graduate and co-author — through a spin - off company.

Lead author Dean Ho, a biomedical engineer at Northwestern University in Evanston, Illinois, says that one of the major challenges in chemotherapy is when tumor cells develop mechanisms to pump drugs right back out.

«Starting with pluripotent stem cells that are not muscle cells, but can become all existing cells in our body, allows us to grow an unlimited number of myogenic progenitor cells,» said Nenad Bursac, professor of biomedical engineering at Duke University.

For many years scientists and engineers have been trying to provide low - cost solar energy by developing a cheap solar cell that is both highly efficient and at the same time simple to build, enabling it to be mass produced.

Engineers at Rutgers - New Brunswick and the New Jersey Institute of Technology worked with a hydrogel that has been used for decades in devices that generate motion and biomedical applications such as scaffolds for cells to grow on.

A collaboration of nanoengineers and electrical and computing engineers at the University of California, San Diego in La Jolla combined their expertise to create the small device that detects alcohol levels and transmits that information to a cell phone or other monitoring station.

In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a «roadmap» for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

«In our experiments, our nanoparticles successfully delivered a test gene to brain cancer cells in mice, where it was then turned on,» says Jordan Green, Ph.D., an assistant professor of biomedical engineering and neurosurgery at the Johns Hopkins University School of Medicine.

«To date, there has been no systematic means of assessing the fidelity of cellular engineering — to determine how closely cells made in a petri dish approximate natural tissues in the body,» says George Q. Daley, MD, PhD, Director of the Stem Cell Transplantation Program at Boston Children's and senior investigator on both studies.

Chun - Chao Chen, a graduate student in the UCLA materials science and engineering department who is the paper's primary author, said using transparent and semi-transparent cells together increases the device's efficiency, and that the materials were processed at low temperatures, making them relatively easy to manufacture.

«CellNet will also be a powerful tool to advance synthetic biology — to engineer cells for specific medical applications,» says James Collins, PhD, Core Faculty member at the Wyss Institute and the William F. Warren Distinguished Professor at Boston University, co-senior investigator on one of the studies.

Meanwhile Coussens and her colleagues at U.C.S.F. found in a 2005 study, published in Cancer Cell, that the removal of antibody - making B cells from mice engineered to be prone to skin cancer prevented the tissue changes and angiogenesis that are prerequisites for disease progression.

By varying the compositions of lipids, cues, and diffusible factors in the scaffolds, we engineered a very versatile and flexible platform that can be used to amplify specific T cell populations from blood samples, and that could be deployed in existing therapies such as CAR - T cell therapies,» said Mooney, Ph.D., a Core Faculty member at the Wyss Institute and leader of its Immunomaterials Platform.

«We have discovered that by inserting a very thin film of gallium arsenide into the connecting junction of stacked cells we can virtually eliminate voltage loss without blocking any of the solar energy,» says Dr. Salah Bedair, a professor of electrical engineering at NC State and senior author of a paper describing the work.

The team of medical and engineering researchers at The Ohio State University previously determined that modifying a single gene to reduce this protein's level in breast cancer cells lowered the cells» ability to migrate away from the tumor site.

The proposed clinical trial, in which researchers would use CRISPR to engineer immune cells to fight cancer, won approval from the Recombinant DNA Advisory Committee (RAC) at the U.S. National Institutes of Health, a panel that has traditionally vetted the safety and ethics of gene therapy trials funded by the U.S. government and others.

Unlike transplanted beta cells — or other types of real cells genetically engineered to release insulin for diabetes treatment (SN: 1/15/11, p. 9)-- these artificial cells could be mass - produced and have a much longer shelf life than live cells, says study coauthor Zhen Gu, a biomedical engineer at the University of North Carolina at Chapel Hill.

Now head of her own lab at Stanford, Heilshorn engineers proteins to aid neural stem cells in healing injured brains and spines.

«This graphene system is able to detect the level of activity of an interfaced cell,» says Vikas Berry, associate professor and head of chemical engineering at UIC, who led the research along with Ankit Mehta, assistant professor of clinical neurosurgery in the UIC College of Medicine.

Emotiv solved this brain — computer interface problem with the help of a multidisciplinary team that included neuroscientists, who understood the brain at a systems level (rather than individual cells), and computer engineers with a knack for machine learning and pattern recognition.

Rechargeable batteries are too heavy for the job, so engineers are planning to try a technology that would use current to separate water into oxygen and hydrogen during the day, and then reverse the process at night via fuel cells to produce electricity.