The 2 - day dedicated conference track provides both strategic insight on cutting edge banking business models and financing opportunities as well as scientific / technical updates on the very latest clinical applications and
cell expansion approaches.
Not exact matches
In a series of side - by - side comparisons, Mooney's team demonstrated that APC - mimetic scaffolds performed better than methods involving commercially available
expansion beads (Dynabeads), which are currently used in clinical adoptive
cell transfer
approaches.
In this study, using a mouse transgenic
approach, the scientists demonstrated that ILC2s express a checkpoint molecule, known as «PD - L1», that functions to control the
expansion of allergy - inducing Th2
cells and the development of allergic pulmonary and gut tissue inflammation.
The
approach enabled a wide range of studies of human brain development, including implicating a new class of neural stem
cell recently discovered by the lab in the evolutionary
expansion of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.
By combining SNP - targeting allele - specific silencing and gain - of - function
approaches, we showed that a 46 - glutamine
expansion in human HTT was sufficient for a dominant - negative effect on spindle orientation and changes in the distribution within the spindle pole and the
cell cortex of dynein, p150Glued and NuMA in neural
cells.
Specific
approaches taken to overcome these challenges including optimizing
cell processing steps such as isolation, washing,
expansion, enrichment, labelling and purification.
We subsequently used a novel Design of Experiments
approach to finely tune the optimal memory B
cell expansion and differentiation conditions for human memory B
cell subsets.