Sentences with phrase «cell experiments involving»

Live - cell experiments involving translational research concepts, such as testing for ischemia - reperfusion in cells for research on stroke, involve a tight regulation of oxygenation as measurements are made in real time.

Not exact matches

Now experiments suggest genes involved in cell stickiness may have given our brain its folds

► The U.S. National Institutes of Health (NIH) has put funding on hold for experiments that involve «mixing human stem cells into very early animal embryos and letting them develop» while it «reconsiders its rules» for this type of research, Gretchen Vogel reported Wednesday.

In August, federally funded work on stem cells was temporarily suspended after a judge ruled that work on hESCs violates a legal amendment in 1995 forbidding funding of any experiments that involve destruction of human embryos.

The first key experiment involved removing a specific subset of activated T - cells from mouse models.

In one experiment this year, a team led by another CRISPR pioneer, Feng Zhang of the Broad Institute in Cambridge, Massachusetts, targeted the 20,000 or so known human genes, turning them on one by one in groups of cells to identify those involved in resistance to a melanoma drug.

All of these findings were supplemented with several other experiments that were designed to learn how CHI3L1 interacts with other cells involved in the tissue repair response in both human and mouse lungs.

Lenski's experiment began in 1988 and has, to date, involved nearly 70,000 generations and quadrillions of cells.

In experiments involving mice injected with human GBM cells, the scientists also demonstrated that if either PTEN or DAXX were eliminated, then tumor growth occurred.

Previous experiments have enabled them to decode a signalling pathway involved in adipose cell maturation and to show that calories in the nutrient medium influence this process.

«The biochemical mechanisms of these proteins have been known for years from experiments involving purified protein and DNA, and that's very important, but in this new work we've clarified these proteins» roles in living cells,» said co-senior author Christopher P. Selby, PhD, research assistant professor of biochemistry and biophysics at UNC.

To overcome these limitations, Mooney's lab has been experimenting with a newer approach that involves reprogramming immune cells from inside the body using implantable biomaterials.

That's because experiments conducted on the International Space Station involving cells that line the inner surfaces of blood vessels (endothelial cells) show that microgravity accelerates cardiovascular disease and the biological aging of these cells.

Its first target was the regulatory network involved in controlling the differentiation of THP - 1 cells, a line of human leukemia cells used in laboratory experiments.

The team did several experiments to be sure that the hub cells were involved, including one in which they genetically marked the hub cells and saw the mark appear in the newly formed somatic stem cells — a clear sign that hub cells had divided to make new stem cells.

However, in a final experiment, inhibiting molecules involved in the disruption of glycocalyx components prevented blood vessel leakage in both mice and human cells exposed to DENV NS1.

Zhao's first experiments involved growing cultures of stromal cells, extracting their exosomes and exposing them to cancer cells, which were then monitored for metabolic changes.

Scientists not involved in the chimera experiment, reported in Cell, said it answered a long - standing question.

The Embryonic Stem Cell Research Oversight Committee at UCI also has reviewed the project and will ensure that experiments involving embryonic stem cells serve important research goals and are conducted according to the highest ethical standards.

On Aug. 3, the scientific article in Nature finally gave us some facts about the much - hyped experiments that involved editing the genomes of human embryos at the Center for Embryonic Cell and Gene Therapy at Oregon Health and Science University.

To create equipment for an experiment involving cell movement, Dr. Jonathan Cooper went to an electronics store, an art supply store and a housewares shop.

In this course, trainees will perform experiments involving both classical physiological models, as well as modern reductionist approaches and confocal microscopy to follow trafficking of transporter proteins in cultured cells.

He notes that students are involved in every step of the research process — growing human leukemia cells, performing the experiments, analyzing the data that the experiments generate and interpreting those data as to what they're saying about the cells» genetic network.

Children with asthma have lower vitamin A levels than children without asthma, and the degree of vitamin A deficiency they exhibit is directly proportional to the severity of their asthma.37, 38 In cell experiments, vitamin A eliminates the response of bronchial smooth muscle cells to growth factors that characterizes the asthmatic reaction39 and suppresses the activity of mast cells, which are involved in asthmatic or other reactions mediated by histamine or other inflammatory chemical messengers called leukotrienes.40 Consistent with studies in isolated cells, vitamin A deficiency causes asthmatic bronchial hyper - reactivity in live rats.41

This second set of experiments in cultured muscle cells showed that HMB attenuated a specific pathway involving caspase 3 and 8, PKR (RNA dependent protein kinase), and reactive oxygen species (ROS) known to activate the ubiquitin - protease pathway.

This plan involves the construction of a world - class rapid transit network and experimenting with new energy - ef cient vehicles such as the super capacitor trolleybuses and electric, hydrogen fuel - cell and hybrid buses.