Sentences with phrase «cell failure caused»

Featuring an all - new, inherently safe, highly advanced chemistry that eliminates the likelihood of destructive cell failure caused by an imbalance in cell level voltage and capacity.

Not exact matches

2) scientifically death is the result (natural death) of the imperfect reproduction of cells within our bodies causing organ failure over time.

Cancer stem - like cells are thought to be the root cause of chemotherapy resistance, leading to treatment failure in patients with advanced disease and the triggers of tumour recurrence and metastasis (regrowth).

These misshapen cells get stuck in blood vessels, causing blockages, anemia, pain, organ failure and significantly shortened lifespan.

Attacking its victim's white blood cells, E. chaffeensis causes a disease called ehrlichiosis, characterized by fever, malaise, body aches, and, if left untreated, organ failure.

«Virtual tissue technology reveals new drug target in polycystic kidney disease: Advanced computer simulations show that failures of cell adhesion and inhibition cause two types of kidney cyst formation.»

This power failure, the team found, is caused by disruption to the cells» mitochondria — the tiny powerhouses that fuel all cell life — when they become destabilized during the «resuscitation» period after a heart attack and trigger chaotic cell - to - cell signaling that interferes with the heart's entire electrical network.

They found that reducing the level of VEGF - A in mouse kidney cells caused kidney failure very similar to that seen in women suffering from preeclampsia.

Tests in mice and nonhuman primates had shown TGN1412 to be safe, but when it was injected into humans — in a dose less than 1/500 of what was given to monkeys — it caused a massive release of infection - fighting T cells that overstimulated the patients» immune systems, resulting in multiple organ failure.

«You need a nearly perfect manufacturing process that employs strict quality - assurance methods, because a single cell failure will cause the entire [250 - cell] battery pack to fail,» he says.

«Study finds cause of pulmonary fibrosis in failure of stem cells that repair lungs.»

Anthracycline drugs, such as doxorubicin, are known to cause heart failure because they cause changes in the DNA structure of the heart muscle cells, leading to irreversible cardiac damage.

During fibrosis these cells differentiate into myofibroblasts, causing scarring and organ failure.

Too large a dose can cause congestive heart failure, among other side effects, while a small dose may be overwhelmed by immune cells, which consider doxorubicin a foreign invader.

ARANESP ® is used to treat anemia, a deficiency in the number of red blood cells, caused by chronic kidney failure in patients both on dialysis and not on dialysis.

SMA is a genetic, neuromuscular disease caused by progressive degeneration of nerve cells in the spinal cord that leads to muscular weakness and atrophy and increased risk for early death due to respiratory failure.

Thus, these animals exhibit premature cardiac arrhythmias and stiffening of the arterial wall, and cardiac failure appears to be the main cause of death; yet these tissues are not burdened with an abnormally - high burden of p16Ink4a - senescent cells, and accordingly, ablation p16Ink4a - positive senescent cells in these animals had little tissue - specific or survivorship phenotypic impact.

A failure of normal astrocyte generation by CNS precursor cells has been discovered to be a consequence of the mutations that cause Vanishing White Matter leukodystrophy [7], and dysfunction of astrocytes has also been suggested to be of importance in models of amyotrophic lateral sclerosis [8], forebrain ischemic injury [9], epileptic seizures [10], Huntington's disease [11], tuberous sclerosis [12] and Rett syndrome [13].

The mutations in p53 cause failure of apoptotic mechanisms and deregulate cell proliferation, thereby leading to genomic instability and malignant progression.

Our physicians and scientists are working on a number of initiatives, including collecting blood and bone marrow from patients to better understand the causes of bone marrow failure syndromes and MDS; exploring possible genetic factors that guide medical care; collecting blood and bone marrow to identify specific proteins that are faulty and how these defects relate to clinical complications and outcomes; and clinical trials to improve stem cell transplants for disorders such as dyskeratosis congenita.

The loss of contractile cells and the inability of the adult mammalian heart to regenerate is a major cause of cardiac dysfunction and heart failure.

Since actual cohesion defects will cause mitotic failure (which most surely results in cell death), most of cohesin - associated diseases are believed to be caused by misregulation of the complex's non-canonical functions in replication / transcription.

Failure of satellite cell activation is also believed to cause skeletal muscle loss as these cells fuse with the muscle fibres and maintain their normal functioning.

Specific safety concerns include: (1) Lithium batteries pose both a chemical and electrical hazard — under certain conditions they can overheat and ignite and, once ignited, can be especially difficult to extinguish; (2) the potential for propagation of thermal runaway between cells or batteries in a package and between adjacent packages of batteries; (3) the potential for uncontrolled lithium battery fires to overwhelm the capability of existing aircraft cargo fire protection systems, leading to a catastrophic failure of the airframe; and (4) the potential for venting of combustible gases from lithium ion cells in thermal runaway, which could collect in an enclosed environment and cause an explosion even in the presence of a suppression agent.

KULR Technology has reached agreement with the National Renewable Energy Laboratory (NREL) to be the exclusive manufacturing and distribution partner for the patented Internal Short Circuit (ISC) device which causes predictable battery cell failures in lithium - ion batteries, making them easier to study and, therefore, safer.

INFLAMMATORY BOWEL DISEASE (IBD) The inflammatory bowel diseases (IBD) are the most common causes of chronic vomiting and diarrhea in dogs, and refer to a group of idiopathic, chronic gastrointestinal tract disorders, characterized by infiltration of the lamina propria by lymphocytes, plasma cells, eosinophils, macrophages, neutrophils, or combinations of these cells.12 The diagnosis of IBD requires the comprehensive exclusion of potential causes of gastrointestinal inflammation, including intestinal parasites, small intestinal bacterial overgrowth, bacterial enterocolitis, dietary intolerances or allergies, and neoplasia.12 Failure to eliminate known causes of gastrointestinal inflammation which can mimic IBD can result in frustration for the owner and clinician due to poor responsiveness of the animal to dietary or pharmacologic therapy.

The toxic agent is colchicine (toxic to rapidly dividing cells); the roots or tubers may contain enough toxins to cause serious multi-system organ failure in cats and dogs that chew on them.

Other disinfectants and detergents may cause kidney or liver failure, destruction of red blood cells, and also death.

However, acetaminophen is extremely toxic to cats at even low doses, potentially causing liver failure and damage to red blood cells.

Dr Jean W Dodds, writing in US Dog World, March, 1995, (16) states: «Immune — suppressant viruses of the retrovirus and parvovirus classes have recently been implicated as causes of bone marrow failure, immune - mediated blood diseases, haematologic malignancies (lymphoma and leukemia), dysregulation of humoral and cell - mediated immunity, organ failure (liver, kidney) and autoimmune endocrine disorders — especially of the thyroid gland (thyroiditis), adrenal gland (Addison's disease) and pancreas (diabetes).

Ingestion can also cause anemia (low red blood cell count) and, in severe cases, the anemia may lead to internal organ damage, organ failure or even death.

Liver cell destruction (hepatocellular necrosis), ingestion of toxic products, tainted foods or medications (such as giving Tylenol to cats, medications at too high a dose or a unique reaction to a medication that your veterinarian could not have predicted), lack of liver blood supply (hepatic hypoxia), congestive heart failure and bile duct obstruction can all cause elevated GDH levels in your pet.

For instance, the immune system fights infection but with enough stresses on the body, can cause general inflammation that kills cells, leading to greater immune response and eventually systemic failure.

Overcharging a battery can cause battery cell failure.

While cell failure doesn't always cause fires, it can dry out the battery and make it cease to hold a charge.

Most truck accidents don't just «happen» — they are caused by aggressive drivers, poor driving habits (tailgating, cell — phone use, excessive speed), driving while intoxicated or sleep - deprived, long work shifts and unrealistic schedules, or the failure of the truck's owner to regularly inspect important items like tires, brakes, and lights.

Now fast forward to today, where the failure of a lawyer to answer emails, cell phone calls, and text messages from clients within minutes can cause those clients to question that lawyer's loyalty and competence.