Sentences with phrase «cell fate transitions»
Such series of cell fate transitions of stem cells ultimately lead to the development of a higher eukaryotic organism.
http://www.vds-molecules-of-life.org/
Abstract During muscle regeneration, the conversion of muscle stem cells to terminally differentiated myofibers requires multiple cell fate transitions.
Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.
Not exact matches
We focus on how changes in chromatin structure orchestrate the developmental transitions from fertilization to genome activation to cell fate specification.
The regulation of transcription during the transitions from fertilization to genome activation to cell fate specification is a critical developmental process, yet it is poorly understood.