Sentences with phrase «cell function not»

The feat raises hopes that similar techniques might restore nerve - cell function not only in the human eye, but also in the spine and brain.

Not exact matches

While the mechanisms at play aren't totally understood, he said, young organisms» blood not only contains all sorts of proteins that improve cell function; somehow it also prompts the recipients» body to increase its production of those proteins.

«But at some point we'll be able fabricate a biodevice from a patient's own cells that will duplicate the most important functions of a kidney and that won't be rejected by the patient's immune system.»

That phenomenon isn't a mutiny of the grey cells, it's a simple truth about the way the human brain functions.

Essentially the model reproduces the inner workings of all of the proteins within the organism and allows scientists to see everything from how cells interact with each other to the functions of genes in a larger context that had not been previously understood.

So how could both come about accidentally at the same time and at the same place and not die before a cell formed, which requires some 2,000 proteins for it to function.

Between the two there is a «penumbra,» a sort of bridge where the brain cells although not functioning are recoverable.

RU - 486, which is not for sale in the U.S., blocks cells in the uterus from receiving the natural hormone progesterone, the function of which is to prepare the lining of the uterus to receive and sustain a fertilized egg.

This is called irreducible complexity — and you can't have a cell spontaneously appear via evolution having billions of functions working — it either all works at once together or it dies.

«There's no reason in my mind to think that we're not going to have iPS cells that function as well as embryonic stem cells».

The late Harold G. Wolff, one of our most distinguished neurologists, pointed out that the function of nerve cells was not confined to the function of the brain.

I love biology, every pain staking detail of DNA - one mess up in an amino acid sequence and you get sickle - cell anima, or the proteins don't function correctly.

And not just life — if life is understood to mean a biologically functioning organism, even a single cell is obviously alive — but personhood.

As soon as the nervous system forming in the embryo begins to function as a whole — and not before — the cell colony begins to turn into a genuinely individual animal.

You may not be familiar with its name, but it's an essential nutrient that's needed for communication between cells, and supporting healthy brain function.

And if you don't deny it, then why discredit the fact that food, the very substance that all humans need in order to keep organs functioning, blood pumping, toxins dispelling, cells forming, could be causing severe effects on our health if the wrong foods are eaten?

Sugary drinks and fruit juice shouldn't be consumed because they will ruin your child's appetite for more nourishing food choices at the same time they cause a myriad of health issues, including the suppression of white blood cell (immune) function.

The rectrospectoscope suggests that a pre-labor c / s would have resulted in an easier recovery for me (bad pain for two weeks or so, plus about a year when I couldn't sit properly thanks to a bruised or broken tailbone) and (more importantly) a few more functioning brain cells for my son.

G6PD deficiency is an inherited condition in which the body doesn't have enough of the enzyme glucose -6-phosphate dehydrogenase, or G6PD, which helps red blood cells (RBCs) function normally.

At the same time, the report determined «basic security functions» were not being followed at the North Country prison, including a failure by corrections officers at the front gate to search employees» bag entering the prison, nightly counts of inmates not being conducted at the times, searches of cells that were deemed inadequate and the poor supervisor of inmates by employees and security stagff.

With microRNA - 210 in check, cells regain their normal function and cancer can not grow.

The cells didn't linger long enough to perform one of their chief functions: slathering a fatty molecule called myelin onto neurons like Tom Sawyer whitewashing a picket fence.

That was surprising, he explains, because «fibrillarin resides deep within the nucleolus of the host cell... [where it] methylates ribosomal RNA molecules, which then go on to form ribosomes,» but its full function may not be completely understood.

These tests indicate that myomerger - deficient muscle cells called myocytes differentiate and form the contractile unit of muscle (sarcomeres), but they do not join together to form fully functioning muscle tissue.

However, as it was not functioning adequately due to the mutation, T - cells attacked the patient's own intestinal cells, causing chronic inflammation.

IPS cells have high proliferation rates and are not yet specialized to perform functions, such as being part of the skin.

Some scientists study cells, called primary human trophoblasts, that are isolated from placentas obtained after childbirth, but such cells do not divide, can be more difficult to obtain, and are more difficult to genetically manipulate to learn about biochemical pathways that have a role in placental function, Dr. Coyne said.

«We still don't know very much about how individual cells in the brain coordinate the activity of higher - level function that defines us as humans,» he says.

Until recently it has been difficult to study the role of glial cells in controlling appetite or any other brain function, because scientists haven't developed many techniques for silencing or stimulating these cells, as they have for neurons.

Therefore, therapeutic efforts should not aim to get rid of microglia but rather restore proper function to these cells, Town suggests.

«Even something as seemingly simple as red blood cells that don't have a nucleus evolved a structure and a function that is much more complicated than we can perceive by looking under the microscope,» says Jason Acker, associate director of development for Canadian Blood Services.

To address this challenge, our research group is using nanoparticles not only to deliver more chemotherapy drugs to the target site within cancer cells, but also to compromise the function of the efflux pumps and thereby significantly improve safety and efficacy of cancer therapy.»

«The idea that you can restore function back to where it was lost is relatively new,» he says broadly, not just concerning stem cells.

The protein has long been considered too complex to target with a drug as it also is crucial to proper function of many immune system cells, not just B cells gone bad.

If the necessary ribosome - associated quality control machinery (RQC) does not function properly, defective proteins accumulate and form toxic aggregates in the cytoplasm of the cells.

«This confirmed for us that without properly functioning GRB10 and p70S6K, the cells could not turn off IRS - 2 signaling and M2 production,» says Heller.

But getting pluripotent stem cells to differentiate into a particular type of cell that can function inside the body is not simple.

So something affecting the basic function and metabolism of cells is saying, «Don't become pregnant until you have got your insulin resistance under control».

By understanding how different cells age, Murphy says, researchers may one day not only extend reproduction, but also life span and organ function.

10x's software includes not only the basic functions required to deconvolute the single - cell data, but also a suite of tools for analysis and visualization.

Researchers still don't know how this range corresponds to their versatile functions, but being more like a string than like a lump with keyholes means that a protein can make many contacts with other molecules to regulate the network of signals that drives the cell.

«Before we get too excited about this being a new form of infertility treatment, these cells can not as yet be made into functioning sperm, so we have no idea if they can pass «the acid test» — the ability to fertilise female eggs as is achieved with donor sperm in IVF treatment,» says Malcolm Alison of the London School of Medicine and Dentistry in the UK.

What scientists haven't been able to do is identify how the cells decide which function to fulfil.

In this study, the researchers noted that conventional approaches to modifying organisms to consume novel nutrients constitutively (i.e. with no «off switch») can lead to inefficiencies when the nutrient metabolic pathways are not linked to downstream pathways for stress - responses, cell growth and other functions important for the health of the organism.

In other patients, mutant CFTR proteins that do transit to the cell surface don't function properly.

The findings, which will be published April 28 in Cell Metabolism, highlight the importance of two genes not previously implicated directly in pancreatic function, and show that the pancreas continues to develop and mature during the first decades of life.

The treatment not only led the spinal cord cells to produce and secrete ChABC in large quantities over areas spanning the injury epicenter, it helped to maintain the overall health of the damaged spinal cord and restored hind limb function in the animals within 12 weeks.

DNA is not the only medium for communicating information necessary for cell function.

A virus works with the cell machinery, so it's hard to come up with a drug that doesn't interfere with the cell's normal function.

Potentially explaining why even healthy brains don't function well with age, Salk researchers have discovered that genes that are switched on early in brain development to sever connections between neurons as the brain fine - tunes, are again activated in aging neuronal support cells called astrocytes.