Sentences with phrase «cell fusion in»

Prior results from Snell and his collaborators, as well as other research groups, indicated that HAP2 is necessary for sex cell fusion in the organisms that possess the protein.

Cell - to - cell fusion in plants is rarely seen due to their relatively tough cell walls, according to the researchers.

An international research team has observed cell fusion in flowering plants for the first time in more than a century.

The researchers are building on their current findings, which they say establishes a system for reconstituting cell fusion in mammalian cells, a feat not yet achieved by biomedical science.

Not exact matches

At Key Stage 3 (age 11 to 13 +, Years 7 to 9) schools have to teach: that fertilisation in humans and flowering plants is the fusion of a male and a female cell; about the physical and emotional changes that take place during adolescence; about the human reproductive system, including the menstrual cycle and fertilization; how the foetus develops in the uterus, including the role of the placenta.

Indeed, the ability to clone animals, such as Dolly the sheep, by fusion of an adult cell to an enucleated oocyte demonstrates that the epigenetic programming responsible for maintaining an adult cell in a stable state can be erased by factors present in the cytoplasm of the oocyte.

and as far as Casey is concerned, this PIG is crying for one reason, because she finally has realized that she will never again slide down a pole at Fusions, but instead will spend the next 50 years in a 10 by 10 cell like the animal that she really is.

Researchers then tested cell cultures and mouse models by using a gene editing process called CRISPR - Cas9 to demonstrate how the presence or absence of myomaker and myomerger — both individually and in unison — affect cell fusion and muscle formation.

The researcher Pia Cosma and her team have used the cell fusion mechanism to reprogram the neurons in the retina.

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

Designed for use in spinal fusion surgery of the lower back, Infuse consists of a titanium cage that houses a collagen sponge soaked in bone morphogenetic protein (BMP), a growth factor that signals bone - forming cells to produce new tissue.

Published in the March 31 advance online issue of Cell, their findings reveal that circular RNAs — like their protein counterparts — are also affected by genomic rearrangements in cancer, resulting in abnormal fusions.

By viewing this fusion as another disease imposed onto tumor cells, scientists could devise new therapies against metastasis, the researchers say in the May Nature Reviews Cancer.

Their findings, published in mBio, an online open - access journal of the American Society for Microbiology, reveal key host cell and viral proteins that direct fusion and Ebola infection.

In addition, important dynamic events such as virus - cell fusions are detected automatically.

Concerns about global warming and oil's imminent demise have caused scientists and policy - makers to look for solutions in both the future and the past: to new technologies such as nuclear fusion, multijunction photovoltaics, and fuel cells — and to traditional energy sources such as water power, wind power, and (sustainable) biomass cultivation (coupled with clean and energy - efficient combustion).

The test developed by Garcia for the current study used fluorescent in situ hybridization (FISH) to visualize BRAF and its fusion partner KIAA1549 inside cells, allowing researchers to see when these genes were fused together and when they were apart.

Next on the team's agenda is to explore molecules that are involved in the fusion of synergid cells and endosperm.

Their study is only the third report of plant cell fusion being observed and the first observation since the initial reports in the late 1800s.

However, by combining the capabilities of the Surface Forces Apparatus (SFA)-- a device that can measure the tiny forces generated by the interaction of two surfaces at the sub-nano scale — and simultaneous imaging using a fluorescence microscope, the researchers were able to see in real time how the cell membranes rearrange in order to connect and open a fusion conduit between them.

Among these functions is the transport of lipids and other biomacromolecules between cells via membrane adhesion and fusion — processes that occur in many biological functions, including waste transport, egg fertilization and digestion.

The scientists, Nicole King and Arielle Woznica of the University of California, Berkeley, with collaborators Jon Clardy and J.P. Gerdt at Harvard Medical School in Boston, discovered that within minutes after exposure to a chonodroitin sulfate (CS) lyase produced by V. fischeri, S. rosetta cells aggregate into mass mating swarms, entering into cell and nuclear fusion while duplicating and recombining their genetic material.

An abnormal gene created by the fusion of ETV6 and the RUNX1 gene is one of the most common alterations in childhood ALL and is found in the leukemic cells of 20 to 25 percent of pediatric ALL.

Cell fusion is a process in which one or more cells combine to form a new cell with more than one nuclCell fusion is a process in which one or more cells combine to form a new cell with more than one nuclcell with more than one nucleus.

«We were able to identify the receptor BAI3, a protein at the surface of myoblasts, as one of the crucial missing links in the fusion of muscle cells,» adds Dr. Côté.

This structure shows the two proteins (in red and gold) and sugars (in green) responsible for mediating HIV's fusion with its host cells.

«The frequency of cell fusion events in vivo is not known, although cell fusion is thought to occur under some circumstances such as cell injury, inflammation, and viral infection.

«Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human cells — if you can prevent viral entry of HIV into immune cells, you have won,» says Dr. Blanchard, who is also associate director of Weill Cornell's chemical biology program.

Furthermore, only those fusion - derived IEC - 6 cell clones that had undergone the changes in cellular growth indicative of neoplastic transformation produced tumors in mice.

Coleman added that further research is needed to determine whether cell fusion events between normal human cell types result in genomic catastrophe and neoplastic transformation.

Reporting online May 18 in Science, researchers describe a genetic variant that apparently is responsible for the fusion of two proteins that protrude from the membranes of red blood cells.

The finding that normal fertilization can result in embryos containing cells with different parental sets of chromosomes is a new mechanism for chimerism, which was previously thought to occur only as the result of fertilization errors, for example, the fusion of multiple sperm or eggs to form an embryo.

Cell to cell fusion is known to be extremely rare in plant cells due to the presence of the relatively tough cell wCell to cell fusion is known to be extremely rare in plant cells due to the presence of the relatively tough cell wcell fusion is known to be extremely rare in plant cells due to the presence of the relatively tough cell wcell wall.

This research reveals a new type of cell fusion that is initiated to destroy a particular cell, and enlightens the evolution of sexual reproduction in flowering plants.

«Cell fusion «eats up» the «attractive cell» in flowering plants.&raCell fusion «eats up» the «attractive cell» in flowering plants.&racell» in flowering plants.»

In a new study reported in Cell, an international group of plant biologists at ITbM, Nagoya University and other research institutes, have examined the ovules of plant cells by live - imaging to reveal a novel cell - elimination system based on an unusual cell fusioIn a new study reported in Cell, an international group of plant biologists at ITbM, Nagoya University and other research institutes, have examined the ovules of plant cells by live - imaging to reveal a novel cell - elimination system based on an unusual cell fusioin Cell, an international group of plant biologists at ITbM, Nagoya University and other research institutes, have examined the ovules of plant cells by live - imaging to reveal a novel cell - elimination system based on an unusual cell fusCell, an international group of plant biologists at ITbM, Nagoya University and other research institutes, have examined the ovules of plant cells by live - imaging to reveal a novel cell - elimination system based on an unusual cell fuscell - elimination system based on an unusual cell fuscell fusion.

The study, published online on April 23, 2015 in the journal Cell, outlines the complicated mechanism of communication between plant cells, where an unusual cell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizatCell, outlines the complicated mechanism of communication between plant cells, where an unusual cell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizatcell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizatcell responsible for pollen tube attraction after successful fertilization.

«We have succeeded in perceiving a unique cell fusion mechanism that arises from initial fertilization in flowering plant cells,» says Maruyama.

As neuroscientists David Hubel and Torsten Wiesel of Harvard University discovered in a series of groundbreaking experiments in the 1960s, individual cells in the visual cortex, so - called binocular cells, receive input from both eyes, specifically from corresponding retinal locations, thus providing a mechanism for perceptual fusion.

Although mitochondria, the tiny capsules that produce energy for the cell, are known to play some role in neurodevelopmental and psychiatric disorders, the contribution of mitochondrial dynamics (mitochondrial trafficking, the regulated fusion and fission, and destruction of mitochondria) has been less clear.

The new finding brings a measure of closure to a story that first rocked the science world in February 2004, when Hwang and colleagues at Seoul National University announced they had cloned a female donor's cell by transferring its nucleus into one of her egg cells stripped of its nucleus in a procedure known as somatic cell nuclear transfer (SCNT), and harvested embryonic stem cells from the resulting fusion.

The results suggested a striking degree of similarity, especially in a region called the «fusion loop» that enables the viral proteins to successfully invade a cell.

Scientists have discovered a new «mastermind fusion gene» may be associated with a rare cancer - causing tumor — pheochromocytomas («pheo») and paragangliomas, according to a study published Feb. 13 in Cancer Cell, by researchers at the Uniformed Services University (USU) and the National Cancer Institutes» The Cancer Genome Atlas.

In this week's Nature, Masaru Okabe and Naokazu Inoue and their colleagues at Osaka University report that the protein, which sits on the outside of sperm cells, plays a make - or - break role in the fusion of sperm and eggIn this week's Nature, Masaru Okabe and Naokazu Inoue and their colleagues at Osaka University report that the protein, which sits on the outside of sperm cells, plays a make - or - break role in the fusion of sperm and eggin the fusion of sperm and eggs.

In an important experiment published one year later, Jim Rothman, a Lasker Prize winner in 2002 honored for his work on fusion in non-neuronal cells, provided the experimental support for Scheller's idea by demonstrating that Scheller's VAMP, or as Rothman called it the v - SNARE, interacted with Scheller's syntaxin or t - SNARE, together with a second t - SNARE, to initiate fusioIn an important experiment published one year later, Jim Rothman, a Lasker Prize winner in 2002 honored for his work on fusion in non-neuronal cells, provided the experimental support for Scheller's idea by demonstrating that Scheller's VAMP, or as Rothman called it the v - SNARE, interacted with Scheller's syntaxin or t - SNARE, together with a second t - SNARE, to initiate fusioin 2002 honored for his work on fusion in non-neuronal cells, provided the experimental support for Scheller's idea by demonstrating that Scheller's VAMP, or as Rothman called it the v - SNARE, interacted with Scheller's syntaxin or t - SNARE, together with a second t - SNARE, to initiate fusioin non-neuronal cells, provided the experimental support for Scheller's idea by demonstrating that Scheller's VAMP, or as Rothman called it the v - SNARE, interacted with Scheller's syntaxin or t - SNARE, together with a second t - SNARE, to initiate fusion.

During the course of our work, the studies of Jim Rothman, who received a Lasker Award in 2002 for his work on the cell biology of vesicle fusion, expanded our thinking and injected great enthusiasm into the rapidly growing field of neurotransmitter release.

Rothman had proposed that one of the proteins necessary for his experimental system and for fusion in live yeast cells, NSF, attaches to the membrane through a second protein and its as - yet - unidentified collaborators.

In response to a variety of environmental conditions, a and α cells secrete lipid - modified pheromones that induce cell — cell fusion, and the resulting dikaryon undergoes a dimorphic transition to hyphal growth [28]--[31].

The activity of tyrosine kinases is typically regulated in an auto - inhibitory fashion, but the BCR - Abl fusion gene codes for a protein that is «always on» or continuously activated leading to unregulated cell division (i.e. cancer).

SGC0946 was found to selectively kills cells transformed with the MLL - AF9 fusion oncogene in an in vitro model of leukemia.