«We have succeeded in perceiving a unique
cell fusion mechanism that arises from initial fertilization in flowering plant cells,» says Maruyama.
The researcher Pia Cosma and her team have used
the cell fusion mechanism to reprogram the neurons in the retina.
Not exact matches
One of the
mechanisms being studied is reprogramming through
cell fusion.
The finding that normal fertilization can result in embryos containing
cells with different parental sets of chromosomes is a new
mechanism for chimerism, which was previously thought to occur only as the result of fertilization errors, for example, the
fusion of multiple sperm or eggs to form an embryo.
The study, published online on April 23, 2015 in the journal
Cell, outlines the complicated mechanism of communication between plant cells, where an unusual cell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizat
Cell, outlines the complicated
mechanism of communication between plant
cells, where an unusual
cell fusion induces selective elimination of the cell responsible for pollen tube attraction after successful fertilizat
cell fusion induces selective elimination of the
cell responsible for pollen tube attraction after successful fertilizat
cell responsible for pollen tube attraction after successful fertilization.
As neuroscientists David Hubel and Torsten Wiesel of Harvard University discovered in a series of groundbreaking experiments in the 1960s, individual
cells in the visual cortex, so - called binocular
cells, receive input from both eyes, specifically from corresponding retinal locations, thus providing a
mechanism for perceptual
fusion.
«While it has been previously shown that ATRA's ability to degrade the leukemia - causing
fusion oncogene PML - RAR causes ATRA to stop the leukemia stem
cells that drive APL, the underlying
mechanism has remained elusive,» says Lu.
In recent years, our laboratory has focused much effort on understanding the molecular and cellular
mechanisms regulating muscle
cell fusion.
By engineering an artificial protein that targets the product of such potentially cancer - causing gene
fusions, Hur hopes to trigger immune defense
mechanisms that kill rogue
cells harboring the
fusions.
Others including Randy Schekman had discovered NSF to be important for vesicle trafficking and secretion in yeast, leading Rothman to argue that these proteins are involved in vesicle
fusion in every
cell of the animal kingdom — a universal
mechanism for secretion.
Second - line anti-HIV drugs include co-receptor antagonists and
fusion inhibitors, which prevent viral entry into
cells via different
mechanisms.
Furthermore, we demonstrated
cell -
fusion mediated reprogramming as an efficient therapy for Parkinson's disease, and as
mechanism to control liver regeneration, an organ with high regenerative capacity in mammals (Altarche - Xifro et al eBiomedicine 2016; Pedone et al..
There are numerous, diverse
mechanisms that allow a low frequency of gene movement between species, such as accidental
fusion of
cells between different species, or the injection of DNA by bacteria into plant
cells.
We are also investigating the
mechanisms controlling
cell - to -
cell fusion, and how ploidy is controlled in reprogrammed hybrids.