The experimental plan includes a fine - grained analysis of the different cell populations within these precious tissues using cutting - edge single -
cell genomics methods.
Not exact matches
As costs come down and
methods become more standardized, experts in the field expect single -
cell sequencing to become the new model for both transcriptomic and
genomic studies.
The TruePrime Single -
Cell Whole Genome Amplification (WGA) kit uses a revolutionary multiple displacement amplification method based on the combination of the recently discovered DNA primase Thermus thermophilus (Tth) PrimPol and the extremely processive, high - fidelity Phi29 DNA polymerase (Phi29 DNAP) to amplify uniformly total genomic DNA of either a single cell or a few ce
Cell Whole Genome Amplification (WGA) kit uses a revolutionary multiple displacement amplification
method based on the combination of the recently discovered DNA primase Thermus thermophilus (Tth) PrimPol and the extremely processive, high - fidelity Phi29 DNA polymerase (Phi29 DNAP) to amplify uniformly total
genomic DNA of either a single
cell or a few ce
cell or a few
cells.
«New computer program can help uncover hidden
genomic alterations that drive cancers: Tested on large tumor
genomics database, REVEALER
method allows researchers to connect
genomics to
cell function.»
Using this
method, features of
genomic organization including compartments, topologically associating domains (TADs) and chromatin loops were detected in single
cells when averaged over the genome.
In the PNAS paper, the scientists demonstrated their
method on two
genomics problems, the role of gene enhancers in the fruit fly embryo and alternative splicing in a human - derived
cell line.
Applying these
methods to prostate cancer
cell lines, the researchers found that accurate predictions of drug sensitivity could be achieved using either
genomics data or phosphoproteomics data alone.
Martonvásár Development of new generic plant genotypes to satisfy the needs of the future, based on an internationally acknowledged plant gene pool, and using up - to - date genetic, physiological,
cell and reproduction biological, functional
genomic, biotechnological, plant breeding and crop production
methods.
«We developed a new
method for analyzing the
cell's
genomic material,» he said.
We employ a wide variety of state - of - the - art technologies such as in vivo optical imaging and high - throughput
methods including
cell - based screening,
genomics, and proteomics approaches.
The scientists developed a
method to visualize the repair process based on
genomic sequencing, and with it found good evidence for their hypothesis: In the
cells that lacked GreA, less DNA degradation surrounded the sites of DNA breaks.
DNA from the transfected plasmids was not detected in any established colony using either
method, indicating a lack of
genomic insertion and suggesting that the episomal vectors had been diluted from the
cells over time.
His lab develops novel single
cell genomic and epigenomic
methods to characterize the immune system and develop new targets for immunotherapy.
Another focus area is the development and application of
genomic methods in
cell culture and animal models.
Together with Anna - Maria Divne, I am setting up and establish
methods for single
cell genomics, from single
cell sorting, to whole genome amplification, target screening and sequencing library preparation.Why can you find me on this homepage?
The TruePrime ™ Necrotic
cell - free / exosomal DNA amplification kit uses a novel multiple displacement amplification
method based on the combination of the recently discovered DNA primase TthPrimPol, and the highly processive and high - fidelity Phi29 DNA polymerase, to amplify
genomic DNA starting from
cell - free DNA * obtained from plasma, serum, urine or any other bodily fluid.