Sentences with phrase «cell growth factor»

This activates the mast cells in these organs so that they undergo degranulation, releasing ready - made proteases such as chymase and tryptase, and synthesizing inflammatory mediators (leukotrienes and vascular endothelial cell growth factor [VEGF]-RRB-.

Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte - macrophage colony stimulating factor (GM - CSF), an agent that functions as a white blood cell growth factor, would improve walking performance in patients with symptomatic peripheral artery disease (a form of vascular disease in which there is partial or total blockage of an artery, usually one leading to a leg or arm).

The resulting network of vasculature contained within these deep tissues enables fluids, nutrients and cell growth factors to be controllably perfused uniformly throughout the tissue.

The pervasive vasculature facilitates stem cell differentiation by enabling delivery of cell growth factors throughout all areas of the tissue.

Cancer prevention Researchers have hypothesized that higher intakes of omega - 3s from either foods or supplements might reduce the risk of cancer due to their anti-inflammatory effects and potential to inhibit cell growth factors [60].

Not exact matches

Scientists now recognize that intense exercise helps your brain produce brain - derived neutrophic factor, an important protein that helps stimulate the process of neurogenesis, which is the growth of new brain cells.

Some reports, such as the Open Philanthropy Project's Animal Product Alternatives report and Van der Weele & Tramper (2014) suggest it is unlikely that cultured meats will become cost - competitive with conventional meat.98, 99 One important contributing factor in this conclusion, which is cited in these reports, is the minimum costs of the growth medium necessary for culturing the desired cells.

They found that epigallocatechin gallate, or EGCg, which is found in all tea, inhibits the activity of tNOX, an overactive enzyme that interferes with a cell's divide - and - rest cycle, and can facilitate uninterrupted growth of cancerous cells when combined with other factors.

Similar to capsaicin, tumor necrosis factor is suspected to both induce and reduce cancer cell growth, and was shown to commit cells to survival when stimulating EGFR transactivation mechanisms, indicating that EGFR could act as a molecular switch determining the antiapoptotic effect of tumor necrosis factor (50).

It contains antioxidants, immune cells, growth factors, immunoglobulins.

Epidermal growth factor is a major growth factor that stimulates cell growth.

They found that exercise may help cognition by increasing blood and oxygen to the brain, increasing levels of norepinephrine, and endorphins to decrease stress and improve mood, and increasing growth factors that help create new nerve cells and support synaptic plasticity.

Some growth factors promote the growth of cells in babies» digestive tracts; others help seal up babies» intestines, which protects babies from pathogens and harmful foreign substances.

This bioactive fluid contains numerous factors and live cells that, in concert, promote the growth and well - being of the breastfeeding infant.

«Taken together our findings show that EGF is a key factor present in breast milk that prevents the onset of NEC in two ways: EGF prevents intestinal cells from dying while at the same time restoring the cell growth that promotes gut healing,» says study author Misty Good, M.D., a neonatologist at Children's Hospital of Pittsburgh at the University of Pittsburgh Medical Center.

It's rich in protein, sugar, vitamins and minerals, plus numerous bioactive components — such as hormones, growth factors, enzymes and live cells — to support your baby's healthy growth and development.7

Its particular composition «nutrients with optimal bioavailability, hormonal and enzymatic components, anti-infective, trophic and growth factors, prebiotics and probiotics, biologically active molecules and cells» makes HM uniquely suited not only for term but also for preterm infants.

Human milk is a bodily fluid which, apart from being an excellent nutritional source for the growing infant, also contains a variety of immune components such as antibodies, growth factors, cytokines, antimicrobial compounds, and specific immune cells [9].

ZO ® OSSENTIAL ® GROWTH FACTOR SERUM PLUS is an anti-aging serum with ingredients such as synthetic snake venom neuropeptide, retinol, proteins, antioxidants, plant stem cells, and herbal extracts.

Muotri has found that a growth factor called IGF1 can prompt mini-brains derived from cells from children with Rett syndrome to make extra neural connections.

Alysson Muotri at the University of California, San Diego, and his team created the mini-brains by exposing stem cells taken from the pulp of children's milk teeth to cocktails of growth factors that help them mature.

The best explanation so far, says Henrietta van Praag, a neurobiologist at the National Institute on Aging, is that exercising the heart somehow stimulates growth factors to produce new nerve cells in the brain.

Setton's lab exposed the hiPSCs to a variety of different growth factors and culture media to coax them into first developing markers for, and then fully forming into, notochord cells.

Low - power laser light shined on damaged rat teeth activates growth factors that cue stem cells to generate the tooth constituent dentin, leading to regeneration.

One factor keeping cells in this immature state is the PTEN gene, which suppresses a signalling pathway involved in cell growth.

The cells, which lined the pores of the scaffold, were regularly fed with streams of nutrients, growth factors and oxygen in a bioreactor.

After deciphering this natural differentiation process, the investigators duplicated it in the laboratory dish by adding a sequence of proteins, called growth factors, to the fluid bathing the stem cells.

So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem cells to biodegradable nanoparticles carrying the human gene for vascular endothelial growth factor (VEGF), which attracts blood vessels to injury sites.

In earlier work, Paller's lab had discovered that depleting an enzyme called GM3 synthase made cells particularly sensitive to growth factors and led to normal wound healing despite diabetic conditions.

«To derive lineages, people use soluble growth factors to get the cells to differentiate,» explains Laura Kiessling, a UW - Madison professor of chemistry and biochemistry and stem cell expert.

To get more cells, researchers from Advanced Cell Technology in Worcester, Mass., grew clusters of human embryonic cells in a precise cocktail of growth factors and other cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developmCell Technology in Worcester, Mass., grew clusters of human embryonic cells in a precise cocktail of growth factors and other cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developmcell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific development.

The team found that connective - tissue cells adjacent to colon cancer stem cells secrete growth factors that activate a molecular pathway in other cells that is vital to maintaining stem - cell - like qualities.

Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into mice.

[Praveen R. Arany et al, Photoactivation of Endogenous Latent Transforming Growth Factor — β1 Directs Dental Stem Cell Differentiation for Regeneration] Could a light - based treatment for cavities and chipped teeth eventually be in the offing for people?

«Fibroblast growth factor receptor inhibitors are new therapies being developed in clinical trials for patients whose cancer cells have genetic alterations in this family of genes,» says Roychowdhury, a member of the OSUCCC — James Translational Therapeutics Program.

A new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

IL - 15 is a growth factor for certain kinds of white blood cells including natural killer cells and T cells.

What they discovered was that an inflammatory factor known as TGF - beta (transforming growth factor - beta) can give cancer cells properties of immune cells by supplying the surface of the cancer cell with a receptor that normally only exists on the white blood cells that travel through the lymphatic system.

They first tested the idea that diluting growth factor can prevent cells invading the posterior capsule.

Obesity also alters a person's metabolism, causing growth factor and hormone imbalances that help cancer cells thrive.

Designed for use in spinal fusion surgery of the lower back, Infuse consists of a titanium cage that houses a collagen sponge soaked in bone morphogenetic protein (BMP), a growth factor that signals bone - forming cells to produce new tissue.

And they incorporated into the gel a protein known as vascular endothelial growth factor (VEGF), which encourages the growth of blood vessels into the transplanted cells.

A team at Emory University is embedding electrodes in glass cones filled with nerve - growth factors that encourage brain cells to sprout more dendrites and axons.

To do so they focused on keratinocytes, a specific type of skin cells with a key role in psoriasis because of their abnormal growth and ability to produce large amounts of inflammation promoting factors.

We don't need to use a cocktail of small molecules, growth factors or other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells,» Varghese said.

«CRKII most likely regulates the stability of mutated epidermal growth factor receptors and drives cancer growth by promoting signaling, or communication, within cancer cells,» said Julia Petschnigg, lead author on the paper and a postdoctoral fellow at U of T. «We found that a combinatorial chemotherapy that inhibits those mutated receptors and CRKII could be beneficial in treating lung cancer.»

These strands of instructions could teach our cells to make whatever was needed to treat or prevent disease — virus - slaying antibodies, wastegobbling enzymes, heart - mending growth factors.

These growth factors «urge» the stem cells to become muscle cells.

Of these, connective tissue growth factor a (ctgfa) was expressed in glial cells during a key period of healing, as the cells were actively building bridges across damaged tissue.

«A general message from these studies is that cancer cells benefit from modulating epigenetic factors like SIRT6 by acquiring the ability to override normal cellular growth control patterns,» says Mostoslavsky, an associate professor of Medicine at Harvard Medical School and an associate member at the Broad Institute.