Sentences with phrase «cell identity remained»

Although the functional importance of TCF - 1 in T cells has been known for more than 25 years, the mechanism by which this protein controls T - cell identity remained unknown.

Not exact matches

The existence of cancer stem cells has already been reported in a number of human cancers, explains Professor Jacobsen, but previous findings have remained controversial since the lab tests used to establish the identity of cancer stem cells have been shown to be unreliable and, in any case, do not reflect the «real situation» in an intact tumour in a patient.
It is no longer debated that the chromatin structure is crucial to maintain cell identity, but the how remains.
«But even for the remaining surviving cells, they tend to be overly activated and lose their identity, because they start to behave like non-regulatory T cells.
The identity and function of the fibroblast, a highly prevalent cell type in the heart, have remained poorly defined.
The identity of these cells however, remains to be a mystery to date.
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