The existence of cancer stem
cells has already been reported in a number of human cancers, explains Professor Jacobsen, but previous findings have
remained controversial since the lab tests used to establish the
identity of cancer stem
cells have been shown to be unreliable and, in any case, do not reflect the «real situation» in an intact tumour in a patient.
«But even for the
remaining surviving
cells, they tend to be overly activated and lose their
identity, because they start to behave like non-regulatory T
cells.