To address this, I am building a microscope and developing analytical tools for high resolution live -
cell imaging in Archaea - friendly conditions, i.e. 70 - 80ºC, low pH and minimal photo damage.
Atkinson explains, «Alex's video, «Killing Cancer,» has some of the most advanced — and most exciting —
cell imaging in the world.
Live
cell imaging in Drosophila melanogaster.
Not exact matches
I won't reveal yet who my favorites are, but I will say that these young scientist - founders came up with very creative solutions for preventing infections
in some common surgeries, tackling resistance
in targeted antibody drugs, improving gene vectors for
cell therapies, helping the vision - impaired «see» faces and better read their environments,
imaging hard - to - see spots
in the lungs and other organs, improving genetic risk analysis, and expediting the logistical operations of hospitals.
A veteran of digital
imaging technology, in 1999 he founded Quantitative Imaging Corp. (QImaging), a manufacturer of digital cameras for scientific and industrial uses — the kind, for example, that can detect microscopic, early - stage cancer
imaging technology,
in 1999 he founded Quantitative
Imaging Corp. (QImaging), a manufacturer of digital cameras for scientific and industrial uses — the kind, for example, that can detect microscopic, early - stage cancer
Imaging Corp. (QImaging), a manufacturer of digital cameras for scientific and industrial uses — the kind, for example, that can detect microscopic, early - stage cancer
cells.
«The new Park Nanoscience Center at SUNY Polytechnic Institute provides researchers with greater access to Park Systems» cutting - edge AFM nanoscopic tools, featuring reliable and repeatable high - resolution
imaging of nanoscale
cell structures
in any environment without damage to the sample.»
The researchers set up a system to grow asymmetric nerve
cells in an observation chamber and use live
cell imaging to track how rabies virus particles are transported along the axons.
Observing the
cell in its native state:
Imaging subcellular dynamics
in multicellular organisms
David Monchaud, a chemist at the University of Burgundy
in France, was drawn to multiphoton
imaging for its precision, sensitivity, and ability to image living
cells.
The field of live -
cell imaging has expanded greatly
in recent years, but still faces many challenges, such as how to improve spatial and temporal resolution as well as how to keep
cells healthy for extended periods of time.
«There was this initial thought that [circulating tumor
cells] are only present at late stage,» says Sollier - Christen, but she notes that
in the past year, several studies using more sensitive techniques have found such
cells much earlier
in tumor development, even before the tumor becomes visible by conventional
imaging techniques.
Biologist Ann Cornell - Bell of Viatech
Imaging in Ivoryton, Connecticut, put on display star - shaped
cells, called astrocytes, from the rat hippocampus, a brain region associated with long - term memory.
Thus, light - sheet systems have become the next wave
in live -
cell imaging for many scientists interested
in high - speed cellular activities, such as the firing of neurons or the flowing of blood
cells.
The latest
in live -
cell microscopy — multiphoton
imaging, light - sheet techniques, and technology borrowed from Raman spectroscopy — allow researchers to study living
cells in more detail with less effort.
Huerta also calls attention to fluorescent resonance energy transfer, which he says, «really allowed us to start
imaging processes
in cells as they occur.»
Professor Richard Oreffo added: «Crucially, unlike current standard staining - based methods the stain-less
imaging approach is translatable to the clinic as the stem
cells are not harmed or disrupted
in any way.
Instead, the team used functional magnetic resonance
imaging (fMRI) to detect populations of
cells that seemed to fire as the volunteers played a virtual reality game
in which they had to replace an object
in the location where they originally found it.
«The massive advantage with our stain-less laser - based
imaging approaches is that you can use the stem
cell sample without having to interrupt the developmental process
in real time, you don't need to perform any
cell disruption and there is no photobleaching (fading) which is fairly common with fluorescent material,» Catarina enthused.
Immunohistochemical
imaging of female human amniotic stem
cells incubated with nanoparticles demonstrated a significant increase
in uptake compared to male
cells.
In cellular experiments, live cell imaging was used to monitor VP40 localization in human cell
In cellular experiments, live
cell imaging was used to monitor VP40 localization
in human cell
in human
cells.
The protein's role
in the pathway leading to memory impairment, however, remained unclear until scientists from IMCB utilised live -
cell imaging techniques to elucidate the mechanism of memory impairment and illustrated how SNX27 attributes to synaptic dysfunction.
After
imaging defiant metastatic
cells in the brains of mice, researchers noticed that the
cells that were able to survive grew on top of blood capillaries, each
cell sticking closely to its vessel «like a panda bear hugging a tree trunk,» Dr. Massagué says.
To surmount this hurdle, Dr. Hodgson and his colleagues
in the Gruss Lipper Biophotonics Center at Einstein devised a new fluorescent protein biosensor that, combined with live -
cell imaging, revealed exactly when and where Rac1 is activated inside cancer
cells.
Earlier, for his Ph.D., he used his physics training to study biological interactions at the molecular resolution — but for his postdoc he changed approaches dramatically, turning to
cell biology and applying his skills to the development of high - resolution functional
imaging of DNA transcription
in living
cells.
Modern brain -
imaging techniques that track blood flow and
cell activity indicate the precuneus is involved
in imagination, self - consciousness and reflecting on memories.
When Conklin joined his lab, he had no experience
in his PI's core area of cancer research, but he brought valuable expertise
in cell imaging techniques.
In this way, Louvard believes the institute will gain most from its mix of research disciplines and potential for translational research, involving anything from theoretical physics and pharmacochemistry through
cell biology and radiobiology to
imaging and bioinformatics.
Using chemicals like these
in combination with new
imaging tools, such as the multi-photon confocal microscope, has enabled researchers to explore the minuscule world of the neuron and observe brain
cells in action with far more precision.
The Systems Biology Group at the Pacific Northwest National Laboratory
in Richland, Washington, employs 90 - plus staff scientists working on proteomics, microbial -
cell dynamics,
cell and molecular
imaging and spectroscopy, computational biology, and bioinformatics.
The gold - iron oxide core - shell nanorods may be useful
in cancer therapy, with MRI
imaging enabled by the iron oxide shell, and local heating created by the photothermal effect on the gold nanorod core killing cancer
cells.
Using an advanced
imaging technique called intravital microscopy, the researchers followed the movement and interaction of HIV - infected
cells in the spleen of mice.
Scientists at Barrow Neurological Institute have recently made discoveries about use of a new technology for
imaging brain tumors
in the operating room — a finding that could have important implications for identifying and locating invading
cells at the edge of a brain tumor.
Quantum dots, which have use
in diverse applications such as medical
imaging, lighting, display technologies, solar
cells, photocatalysts, renewable energy and optoelectronics, are typically expensive and complicated to manufacture.
To better determine the role of specific chemoattractants
in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow
in Luster's lab, used multiphoton intravital microscopy — an
imaging technology pioneered for studies of immune
cell movements
in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow
in real time the development of IC - induced arthritis
in a mouse model of rheumatoid arthritis.
Using a novel approach for
imaging the movement of immune
cells in living animals, researchers from the Massachusetts General Hospital (MGH) Center for Immunology and Inflammatory Diseases (CIID) have identified what appear to be the initial steps leading to joint inflammation
in a model of inflammatory arthritis.
«Major innovation
in molecular
imaging delivers spatial and spectral info simultaneously: Combines spectroscopy with super-resolution microscopy, enabling new ways to examine
cell structures.»
To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single
cells based on stimulated Raman scattering (SRS)
imaging, and demonstrated its use
in live cancer
cells, tumor xenograft tissues, primary neurons and mouse brain tissues.
In a study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body
In a study presented
in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body
in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT
imaging to show that the amount of
cell - free tumor DNA circulating
in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body
in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer
in the body
in the body).
Proteins from jellyfish and corals that fluoresce
in the visible wavelength range have revolutionized optical
imaging of
cells.
These infrared fluorescent proteins are expressed well
in mammalian
cells and mice, and can be used for whole - body
imaging.
«We have shown that pericytes initiate the increase
in blood flow seen when nerve
cells become active, so we now know that functional
imaging signals are caused by a pericyte - mediated increase of capillary diameter.
This method has already been used successfully to reach a maximum resolution
in the
imaging of
cells.
Because calcium
imaging is widely used to identify
cells in tissues throughout the body, researchers studying other systems will be able to benefit from the published methodology.
Through the new
imaging technology, researchers use fluorescent
imaging to locate proteins and other molecules
in cells and tissues.
Although the technique may find uses
in many diverse fields, two of the most exciting possibilities are localized optical spectroscopy of semiconductors and the fluorescence
imaging of living
cells.
The researchers were able to trace the development of these two
cell types with unprecedented clarity by advancing very powerful
imaging techniques that are available
in the fruit fly.
To determine the most common type of age - related segregation errors, the researchers first used a novel high resolution
imaging technique to visualize chromosomes
in live mouse egg
cells throughout the whole first stage of meiosis.
The detection and
imaging of protein - protein interactions
in live
cells just got a lot more colorful, thanks to a new technology developed by University of Alberta chemist Dr. Robert E. Campbell and his team.
«The
imaging system, developed by Dr. Young while at the University of Pittsburgh, pinpoints the spatial and temporal location of HIV -1-infected
cells in the body, allowing us to observe HIV - 1 replication
in real - time and to essentially see HIV - 1 reservoirs
in latently infected
cells and tissues,» Dr. Khalili explained.
The study, which was led by postdoc Gregor Pilz and PhD student Sara Bottes, used
in vivo 2 - photon
imaging and genetic labeling of neural stem
cells in order to observe stem
cell divisions as they happened, and to follow the maturation of new nerve
cells for up to two months.