Sentences with phrase «cell imaging techniques»

Experimental approach: To use patient - specific induce pluripotent cell models from a (i) storage disease (NCL), (ii) aggregate prone disease (ALS) and (iii) a disease with no aggregates but hyperexcitability (ChAc) combined with state of the art live cell imaging techniques, electrophysiology and biophysical tools (PIV, laser ablation for cortex tension measurements, AFM).

Aim 3: We are specifically interested how defects of nuclear proteins cause axonal phenotypes using live cell imaging techniques, inhibitor studies, laser irradiation, - omics approaches.

Colocalization analysis in fluorescence microscopy Cell Imaging Techniques (pp. 97 - 109): Springer.

Nagoya, Japan — Dr. Daisuke Maruyama and Professor Tetsuya Higashiyama at the Institute of Transformative Bio-Molecules (WPI - ITbM) of Nagoya University and the JST - ERATO Higashiyama Live - Holonics Project along with their international team have shown by live - cell imaging techniques that flowering plants, such as Arabidopsis thaliana undergo a cell to cell fusion to prevent the attraction of the second pollen tube after fertilization has occurred.

Other advances that gave the researchers a clearer view of the signaling mechanisms reported in Science include CRISPR gene editing, live - cell imaging techniques, and more powerful ways to look at all components of a protein complex.

When Conklin joined his lab, he had no experience in his PI's core area of cancer research, but he brought valuable expertise in cell imaging techniques.

The protein's role in the pathway leading to memory impairment, however, remained unclear until scientists from IMCB utilised live - cell imaging techniques to elucidate the mechanism of memory impairment and illustrated how SNX27 attributes to synaptic dysfunction.

Not exact matches

«There was this initial thought that [circulating tumor cells] are only present at late stage,» says Sollier - Christen, but she notes that in the past year, several studies using more sensitive techniques have found such cells much earlier in tumor development, even before the tumor becomes visible by conventional imaging techniques.

A new 3 - D imaging technique enables viewers to track the life of living cells — how they grow and move around — without disturbing them.

A new computer - imaging technique shows researchers how brain cells communicate — one molecule at a time

The latest in live - cell microscopy — multiphoton imaging, light - sheet techniques, and technology borrowed from Raman spectroscopy — allow researchers to study living cells in more detail with less effort.

Modern brain - imaging techniques that track blood flow and cell activity indicate the precuneus is involved in imagination, self - consciousness and reflecting on memories.

The technique could also be modified for microscopy, allowing imaging of photosynthesis inside the plant cells.

Using an advanced imaging technique called intravital microscopy, the researchers followed the movement and interaction of HIV - infected cells in the spleen of mice.

Diagnosing cancer today usually involves various imaging techniques, examining tissue samples under a microscope, or testing cells for proteins or genetic material.

Although the technique may find uses in many diverse fields, two of the most exciting possibilities are localized optical spectroscopy of semiconductors and the fluorescence imaging of living cells.

The researchers were able to trace the development of these two cell types with unprecedented clarity by advancing very powerful imaging techniques that are available in the fruit fly.

To determine the most common type of age - related segregation errors, the researchers first used a novel high resolution imaging technique to visualize chromosomes in live mouse egg cells throughout the whole first stage of meiosis.

The team used an imaging technique that allowed them to view the responses of over 100 Kenyon cells at a time and, importantly, quantify their results.

Using a powerful imaging technique that allowed the scientists to track the presence and movement of parasites in living tissues, the researchers found that Toxoplasma infects the brain's endothelial cells, which line blood vessels, reproduces inside of them, and then moves on to invade the central nervous system.

«We showed with this technique that we can detect very tiny tumors of just a few hundred cells,» Lu said, adding that the study pushed imaging boundaries, revealing smaller cancers than can be detected with current clinical imaging modalities.

I also think that the next revolution in science might be new imaging techniques to observe our cells and molecules in real time within the entire body during infections or cancer or even while we watch our favorite movie star on video in our doctor's office.

One infrared scan can give pathologists a window into the structures and molecules inside tissues and cells, enabling fast and broad diagnostic assessments, thanks to an imaging technique developed by University of Illinois researchers and clinical partners.

In this role, she works with many collaborators to facilitate implementing superresolution microscopy into their research programs as well as developing novel techniques for microbial live cell imaging.

But several new imaging techniques at a range of resolutions provide new views — and new understanding — of how cells function.

learn from our speakers the benefits of imaging live cells using techniques such as high resolution microscopy, superresolution microscopy, and high - content analysis

The breakthrough came with a new imaging technique, dual - resonance - frequency - enhanced electrostatic force microscopy (DREEM), which was developed by University of North Carolina at Chapel Hill chemist and co-author Dorothy Erie, former UNC and NC State postdoctoral researchers Dong Wu and Parminder Kaur, and was featured earlier this year in Molecular Cell.

By making the switch, all molecules made from fatty acids can be observed inside living cells by an advanced imaging technique called stimulated Raman scattering (SRS) microscopy.

In fact, cell biologists require an entire toolbox of imaging techniques in order to get the answers they want.

Imaging techniques that rely on light — such as taking pictures of cells tagged with a «reporter gene» that codes for green fluorescent protein — only work in tissue samples removed from the body.

Another popular technique for 3D cell imaging called spinning disc confocal microscopy can't image samples nearly as long as Betzig's technique, but it is still better for imaging thick cells and tissue.

«We hope it will ultimately do for ultrasound what green fluorescent protein has done for light - based imaging techniques, which is to really revolutionize the imaging of cells in ways there were not possible before.»

The microscopy techniques that permit imaging of brain cells in awake mice generally can't visualize anything deeper than a fraction of a millimeter below the brain's surface, whereas the mPOA is several millimeters deep.

Phase imaging is a technique that translates the changes in the phase of light caused by cells and their organelles into refractive index maps of the cells themselves.

Many medical imaging techniques focus on anatomical structures, but positron emission tomography (PET) is different: It produces pictures that highlight what cells are doing.

Imaging techniques are becoming ever more important in the fields of cellular immunotherapy and stem - cell transplantation, the researchers say.

«This study is a great example of a highly collaborative endeavor that combines expertise in systems RNA biology, stem cell and neuronal biology, physiology, and cutting - edge imaging techniques.

«Imaging techniques set new standard for super-resolution in live cells.»

The group combines several cutting - edge single molecule imaging techniques to study how protein organization, dynamics and stoichiometry relate to protein function in several fundamental biological processes, such as intracellular transport, autoimmune neurological disorders or stem cell reprogramming.

These nonlinear imaging techniques have been shown to be useful for clinical diagnostics, including identifying cancerous cells, but it has been difficult to miniaturize the required instrumentation for use inside the body.

Immune cells called microglia activate as part of the body's inflammatory response, so the researchers used a brain imaging technique to measure a substance that increases in activated microglia.

The researchers used a 2 - photon photolysis technique that can be performed in vivo, together with imaging, to manipulate and monitor neuronal activity at single - cell resolution.

What makes this technique novel is the accompaniment of an imaging agent known as Ga - 68 DOTATOC, which binds to somatostatin receptors in neuroendocrine cells that use the hormone somatostatin to mediate endocrine function, the release of neurotransmitters and cellular proliferation.

The researchers used electron microscopy and other imaging techniques to view thousands of cells from the liver tissue of lean and obese mice.

In their January publication in the Journal of Neurophysiology, researchers Michael A. Gaffield, Ph.D., Samanta B. Amat, and Jason M. Christie, Ph.D., describe the modification of imaging and behavior techniques allowing them to monitor the activity of Purkinje cells over seven consecutive weeks during the course of a motor association task, in particular, the licking behavior of mice.

The new imaging technique will allow researchers to see the effects of novel drugs on this final stage in the parasite's invasion strategy, researchers report online on this week in Cell Host & Microbe.

The LOCI lab specializes in developing new imaging techniques for living things, with a special interest in studying cells in their microenvironment rather than in isolation.

For years researchers have been developing molecular imaging techniques that visualize hormonally active breast cancer cells — specifically those testing positive for human epidermal growth factor receptor 2 (HER2).

A new technique enables 3 - D visualization of chromatin (DNA plus associated proteins) structure and organization within a cell nucleus (purple, bottom left) by painting the chromatin with a metal cast and imaging it with electron microscopy (EM).

Ueda, Kurihara and their colleagues improved the resolution of this imaging technique to be able to observe the internal structure of the cell.