Sentences with phrase «cell imaging with»

The authors of this study combined live cell imaging with electron microscopy to observe Trichoplax feeding behavior at scales ranging from the whole animal to subcellular.

Not exact matches

I won't reveal yet who my favorites are, but I will say that these young scientist - founders came up with very creative solutions for preventing infections in some common surgeries, tackling resistance in targeted antibody drugs, improving gene vectors for cell therapies, helping the vision - impaired «see» faces and better read their environments, imaging hard - to - see spots in the lungs and other organs, improving genetic risk analysis, and expediting the logistical operations of hospitals.

«The new Park Nanoscience Center at SUNY Polytechnic Institute provides researchers with greater access to Park Systems» cutting - edge AFM nanoscopic tools, featuring reliable and repeatable high - resolution imaging of nanoscale cell structures in any environment without damage to the sample.»

Biologist Ann Cornell - Bell of Viatech Imaging in Ivoryton, Connecticut, put on display star - shaped cells, called astrocytes, from the rat hippocampus, a brain region associated with long - term memory.

The latest in live - cell microscopy — multiphoton imaging, light - sheet techniques, and technology borrowed from Raman spectroscopy — allow researchers to study living cells in more detail with less effort.

«The massive advantage with our stain-less laser - based imaging approaches is that you can use the stem cell sample without having to interrupt the developmental process in real time, you don't need to perform any cell disruption and there is no photobleaching (fading) which is fairly common with fluorescent material,» Catarina enthused.

Immunohistochemical imaging of female human amniotic stem cells incubated with nanoparticles demonstrated a significant increase in uptake compared to male cells.

To surmount this hurdle, Dr. Hodgson and his colleagues in the Gruss Lipper Biophotonics Center at Einstein devised a new fluorescent protein biosensor that, combined with live - cell imaging, revealed exactly when and where Rac1 is activated inside cancer cells.

Previously, high - resolution live imaging has been done with cells cultured on glass slides, which flattens samples.

Using chemicals like these in combination with new imaging tools, such as the multi-photon confocal microscope, has enabled researchers to explore the minuscule world of the neuron and observe brain cells in action with far more precision.

The gold - iron oxide core - shell nanorods may be useful in cancer therapy, with MRI imaging enabled by the iron oxide shell, and local heating created by the photothermal effect on the gold nanorod core killing cancer cells.

X-ray-like imaging without the harmful radiation and cell phones with more bandwidth are closer to reality now that researchers have developed a novel type of lens that works with terahertz frequencies.

His research largely focuses on new means to incorporate imaging methods to view cells of brain tumors with a hand held instrument that a neurosurgeon can use to visualize the individual cells during the progress of the operation.

«Major innovation in molecular imaging delivers spatial and spectral info simultaneously: Combines spectroscopy with super-resolution microscopy, enabling new ways to examine cell structures.»

In a study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body).

Continuous measurement and imaging of the intracellular free calcium ion concentration -LRB-[Ca2 +] i) of mitotic and interphase PtK1 cells was accomplished with the new fluorescent Ca2 + indicator fura - 2.

The researchers were able to trace the development of these two cell types with unprecedented clarity by advancing very powerful imaging techniques that are available in the fruit fly.

Intravital two - photon bone imaging is superior compared with conventional analyses of the shape and form of a tissue because it enables two - dimensional scanning in bone in a focal plane to observe cell shapes and the appearance of mOBs and mOCs in the body.

Normal and cancerous brain cells interfaced with graphene show different activity levels under Raman imaging.

«We showed with this technique that we can detect very tiny tumors of just a few hundred cells,» Lu said, adding that the study pushed imaging boundaries, revealing smaller cancers than can be detected with current clinical imaging modalities.

But neither data from brain scanners — functional magnetic resonance imaging — nor clinical studies of patients with implanted electrodes have explained exactly how the cells in these face patches work.

First, imaging experiments revealed that Tregs have a close relationship with the stem cells that reside within hair follicles and allow them to regenerate: the number of active Tregs clustering around follicle stem cells typically swells by three-fold as follicles enter the growth phase of their regular cycle of rest and regeneration.

Using live imaging in zebrafish to track oligodendrocytes in real time, researchers reporting in the June 24 issue of the Cell Press journal Developmental Cell discovered that individual oligodendrocytes coat neurons with myelin for only five hours after they are born.

Dr. Taraska's lab studies the structural cell biology of exocytosis and endocytosis with advanced imaging methods including live cell microscopy, superresolution fluorescence, and electron microscopy.

Optical Coherence Tomography (OCT) imaging revealed the loss of outer segments in foveal cone cells in the «optical gap» of a patient with ATF6A defects.

In this role, she works with many collaborators to facilitate implementing superresolution microscopy into their research programs as well as developing novel techniques for microbial live cell imaging.

By comparison, that's about 15 times smaller than a red blood cell, and Zhang said shrinking an infrared light source to such a small scale could open doors to new kinds of chemical sensing and molecular imaging that aren't possible with today's state - of - the - art nanoscale infrared spectroscopy.

The breakthrough came with a new imaging technique, dual - resonance - frequency - enhanced electrostatic force microscopy (DREEM), which was developed by University of North Carolina at Chapel Hill chemist and co-author Dorothy Erie, former UNC and NC State postdoctoral researchers Dong Wu and Parminder Kaur, and was featured earlier this year in Molecular Cell.

This kind of imaging is impossible with other microscopes; the ones that are fast enough to record rapid movement do not have a high enough resolution to see inside the cells; and other microscopes with similar resolution are just too slow to capture that amount of motion clearly.

Imaging techniques that rely on light — such as taking pictures of cells tagged with a «reporter gene» that codes for green fluorescent protein — only work in tissue samples removed from the body.

This study shows how these issues have been overcome with a newly developed imaging system, making it possible to image structures as small as 80nm or less anywhere in the cell.

The group of imaging specialists led by Prof. Michael Schäfers, Coordinator of the Cluster of Excellence, labelled the cells thus obtained with various fluorescent dyes in order to be able to study them in living organisms — initially with the optical method of fluorescence reflectance imaging.

Using this, the researchers performed 3D super-resolution imaging of stained structures in the cells, and combined it with 3D label - free phase imaging.

Nagoya, Japan — Dr. Daisuke Maruyama and Professor Tetsuya Higashiyama at the Institute of Transformative Bio-Molecules (WPI - ITbM) of Nagoya University and the JST - ERATO Higashiyama Live - Holonics Project along with their international team have shown by live - cell imaging techniques that flowering plants, such as Arabidopsis thaliana undergo a cell to cell fusion to prevent the attraction of the second pollen tube after fertilization has occurred.

The researchers used a 2 - photon photolysis technique that can be performed in vivo, together with imaging, to manipulate and monitor neuronal activity at single - cell resolution.

«The high efficiency of the materials along with cheap, scalable synthesis makes them very attractive as next generation emitters for fluorescent lamps, LEDs and for biological imaging, for example for highlighting tumours or cell division.»

The LOCI lab specializes in developing new imaging techniques for living things, with a special interest in studying cells in their microenvironment rather than in isolation.

Through imaging of the liver in animal models, scientists discovered that platelets are constantly interacting with the Kupffer cells by «touching» them to search for captured bacteria.

Contact: 508-289-7139; [email protected] WOODS HOLE, Mass. — Using a simple «mirror trick» and not - so - simple computational analysis, scientists affiliated with the Marine Biological Laboratory (MBL) have considerably improved the speed, efficiency, and resolution of a light - sheet microscope, with broad applications for enhanced imaging of live cells and embryos.

A new technique enables 3 - D visualization of chromatin (DNA plus associated proteins) structure and organization within a cell nucleus (purple, bottom left) by painting the chromatin with a metal cast and imaging it with electron microscopy (EM).

They found that injecting into the carotid artery breast cancer cells that express markers allowing them to enter the brain — cells labelled with bioluminescent and fluorescent markers to enable tracking by imaging technologies — resulted in the formation of many metastatic tumors throughout the brain, mimicking what is seen in advanced breast cancer patients.

The injected cells express markers that allow them to enter the brain and are labelled with bioluminescent and fluorescent markers to enable tracking by imaging technologies.

The laboratory is working in collaboration with Dr. Paula Foster to develop real - time cellular magnetic resonance imaging techniques as a means to track dendritic cell migration in vivo in humans.

IDMIT is an infrastructure for preclinical research in infectious diseases and immunology which is certified ISO9001 and which includes 1) A large animal facility with capacity to host NHP in BSL2 and BSL3 containment, 2) State - of - the - art laboratories for cell biology, immunology, molecular biology, flow cytometry and mass cytometry (CyTof), cell - sorting and confocal microscopy in BSL3 containment; 3) A biological resources centre with high storage capacity; 4) Highly innovative technologies for in vivo imaging of large animals in BSL2 and BSL3 containment, including a two - photon microscope, a PET - CT facility, and several optic based technologies (fibered endo - microscopy, near infra - red imaging).

Using a combination of molecular biology, biochemical and novel multi-dimensional digital imaging approaches we study in real - time complex multi dimensional signal integration during the interaction of T cells with live antigen - presenting cells.

Institutional needs for flow cytometry services were carefully evaluated and a decision was made to transition the operation of the South Campus Flow Cytometry and Cell Sorting Facility to an institutional core to provide the Flow Cytometry and Cellular Imaging Core with sufficient capacity needed to support the institution's investigators.

These questions will be addressed by combining unbiased «omics» - approaches (i.e. genomics, transcriptomics, and proteomics) and a targeted genetic analysis with both superresolution live - cell imaging and electron microscopy of nanotube - forming cells.

The team has access to state - of - the - art laboratories and animal facilities with BSL2 and BSL3 containment, flow cytometry, cell sorting, histopathology and in vivo imaging (IVIS).

We are also equipped with advanced imaging system technology offering non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in relevant models using non-virulent mycobacteria tagged with bioluminescense genes.

We exploit chick and mouse embryo animal models, combined with live imaging, cell and tissue cultures and molecular approaches.