Sentences with phrase «cell in a dish»

A cell in my brain is different from a cell not in my brain but, say, in a culture of cells in a dish.
Usually, converting human skin cells to functional brain cells in a dish takes around 50 days.
To do this, human stem cell lines could be treated to differentiate into human heart cells in a dish.
Thus, the technique could produce adult muscle cells in a dish that carry genetic diseases.
On the other hand, cells in a dish lack the critical element of realistic 3 - D structure.
So you'd want many more cells in a dish that are beating and with the right cell type.
«They are a bunch of cells in a dish, like a soup,» he says.
The researchers are the first to grow human vaginal skin cells in a dish in a manner that creates surfaces that support colonization by the complex good and bad communities of bacteria collected from women during routine gynecological exams.
To confirm these findings, the team infected human cells in dish with two forms of CMV — one of which could generate the IE2 accelerator circuit and one that could not.
Next, the research team will examine specifically whether these liver cells obtained from human embryonic stem cells in a dish help repair injured livers in preclinical animal models of liver disease.
«Our hydrogel has many applications: it could be used as a scaffold to grow cells or it can be incorporated with cells in a dish and then injected to stimulate tissue growth,» said Annabi.
Experiments on cells in dishes revealed that chronic exposure to corticosterone changed the RNA in these vesicles.
He also notes that the fluorescence imaging meant to demonstrate the presence of PGC - like cells in the dish doesn't seem to show proteins necessary for that type of cell, meaning the authors may not really have created the PGC - like cells they would need to generate sperm.
When human stem cells develop into beta cells in a dish, they only reach a precursor stage, unable to fully mature; this prevents them from effectively producing insulin in response to glucose.
«Once stem cells can be established it may be possible to learn about the genetic basis of traits by studying cells in a dish rather than in the dogs themselves,» he says.
«The final step was the most unique — and the most difficult — as molecules had not previously been identified that could take reprogrammed cells the final step to functional pancreatic cells in a dish
Avivi's team has found out that fibroblast skin cells from the armpits of the rats can kill human cancer cells in a dish.
They used mice and cartilage cells in a dish to study one mutant form of IDH that is identified only in cartilage cells.
They grew human hippocampal progenitor cells in a dish and added sertraline.
The team, led by neurologist Douglas Kerr, cultivated rat embyronic stem cells in a dish until they developed into neural precursors.
«What we show is that the Zika virus infects neuronal cells in dish that are counterparts to those that form the cortex during human brain development.»
Both normalized progeria cells in a dish and treated mice with a version of the disease.
These synthetic ubiquitin variants act quickly, completely eliminating MERS from cells in a dish within 24 hours.
Researchers commonly use electroporation, a technique that uses an electric pulse to momentarily create pores that allow the Cas9 protein and guide RNA complex to slip inside cells in a dish.
Although it was first used to edit human cells in a dish back in 2013, writes MIT Technology Review, since then not a lot has actually been done to test it out on humans.
But compared to a homogeneous material like water or a magnet — or even a collection of identical cells in a dish — cancer is a hot mess.
This discovery, which earned Dr. Yamanaka the 2012 Nobel Prize in Physiology or Medicine, has revolutionized the fields of stem cell biology and regenerative medicine and has allowed scientists to model disease from patient - derived cells in a dish, thus working towards a new era of personalized medicine.
Critically, the scientists confirmed that this biological pathway is identical in animal models and in the human disease cells in a dish, forwshadowing the potential future elimination of animal model testing for ALS and other diseases.
We might be able to grow a single layer of duck liver cells in a dish, but not foie gras that someone would be happy to eat.
«You can grow heart cells in a dish but they won't beat well enough to pump blood,» Taylor says.
Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.
One metabolite featured in the study is cholesterol sulfate, which was found to be used up during osteogenesis on a rigid matrix and in turn could be used to convert stem cells into bone - like cells in a dish.
«Researchers create insulin - producing beta cells in a dish
One benefit of studying cells in a dish, rather than studying actual people, is that you can limit variables, Goniewicz says.
The research method Dr Nicholas used is unlike other techniques, which separate and grow a single layer of cells in a dish.
«This is one of the few examples in the entire field of pluripotent - stem - cell research where a fully functional cell type has been unequivocally generated starting from a pluripotent stem cell in a dish,» says Clark.
Biologists rely on animal models to answer important questions that can't be addressed with cells in a dish.
The usual approach is to grow human cells in a dish, to infect and try to treat them there, but this is not possible with liver cells or hepatocytes.
«They are more true - to - life than cells in dishes and more human - like than animal models,» said Hamilton.
The research team tested the cells in dishes that were treated with luteolin and found that migration was inhibited by the plant compound.
When delivered to cells in a dish, IL - 2 sticks around for a long time, amplifying the response of natural killer cells against cancer cells.
However, it turned out that the new compound, which the group named teixobactin, was not toxic to human cells in a dish.
In 2013, the lab of Peter Walter, a biochemist at the University of California, San Francisco (UCSF), discovered a compound — called ISRIB — that blocked the stress response in human cells in a dish.
Investigations into human brain development using human cells in the culture dish have so far been very limited: the cells in the dish grow flat, so they do not display any three - dimensional structure.
The researchers then extracted stem cells from the embryos and grew the cells in dishes in the lab.
In the first part of their experiment they simulated the type of cell death that occurs in stroke by adding a chemical to brain cells in a dish.
Compared with laboratory mice or cells in a dish, primates can provide deep insight into complex behaviors, infectious diseases, or neuropsychological ailments that afflict people.
With our new technology, we can quickly create billions of these cells in a dish and then transplant them into damaged hearts to treat heart failure.»
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