Sentences with phrase «cell in the bone marrow»

Blood stem cells in the bone marrow have been labeled with a fluorescent marker protein.
As iron is needed for the production of red blood cells in the bone marrow, many patients develop anemia.
Often this is accompanied by an increase in fat cells in the bone marrow.
Every day, stem cells in our bone marrow produce billions of new red blood cells.
This is achieved by destroying existing cells in the bone marrow using drugs or radiation.
A particularly decisive role in this process is the interactive communication with surrounding tissue cells in the bone marrow.
All of them originate from cells in the bone marrow called stem cells.
The researchers wanted to exploit the abundant supply of stem cells in bone marrow by using stem cells derived from bone marrow.
In some diseases, the blood - forming stem cells in the bone marrow stop working effectively and fail to generate enough new blood cells, or the right types of cells.
One function of testosterone is the stimulation of red blood cells in bone marrow.
The pool of stem cells in the bone marrow is continuously undergoing a process of self - renewal and differentiation.
And, even though the 24p3 inhibitor increased the proportion of healthy cells in the bone marrow, it did not decrease the leukemia cells overall, according to Kharas.
Researchers have designed a nanoparticle - based therapy that is effective in treating mice with multiple myeloma, a cancer of immune cells in the bone marrow.
Of particular concern is the damage done to the blood - forming cells in the bone marrow which suppresses the immune system and promotes the development of secondary cancers like leukemia.
The researchers, led by Professor Sten Eirik W Jacobsen at the MRC Molecular Haematology Unit and the Weatherall Institute for Molecular Medicine at the University of Oxford, investigated malignant cells in the bone marrow of patients with myelodysplastic syndrome (MDS) and followed them over time.
Role of B - Cell — Activating Factor in Adhesion and Growth of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment
Amazingly, the mice that had fasted had no detectible cancer cells in bone marrow and spleen — compared to nearly 68 percent of cells found to be cancerous in the control group.
The liposome is used as a vehicle to transport the drugs into the body and into leukemia cells in the bone marrow.
One such antibody agonist, which can turn stem - like cells in bone marrow into young brain cells, was described in a report in the Proceedings of the National Academy of Sciences last month.
The two plots in the Nature paper show flow cytometry data - a counting up of cells - after exposure to other cells in bone marrow taken from younger and older mice.
(Revlimid) An immunomodulatory and anti-angiogenic agent, this drug slows the growth of blood vessels feeding abnormal cells and kills abnormal cells in the bone marrow.
«The progenitor and stem cells in the bone marrow began massively expanding and effectively turned the bone marrow into a megakaryocyte - making machine,» he said.
This protein causes certain cells in the bone marrow and in the blood to grow uncontrollably, thus allowing the cancer to spread more rapidly.
Cells in the bone marrow then pick up the signal and pre-program monocytes with the appropriate function to either protect or repair.
In 1868, however, the German pathologist Ernst Neumann discovered immature precursor cells in bone marrow, which turned out to be the actual site of blood cell formation, also known as hematopoiesis.
«The control mechanism actually destroyed cells in the bone marrow which were ready to be released.
Stem cells in bone marrow need to produce hydrogen sulfide in order to properly multiply and form bone tissue, according to a new study from the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry.
In both acute and chronic myelogenous leukemia, immature white blood cells in the bone marrow multiply out of control.
Subsequent tests revealed that the retrovirus used to ferry the corrective gene into the DNA of blood - making cells in the bone marrow had lodged in or near a gene that regulates T cells, possibly prompting their uncontrolled growth.
Researchers at the Whitehead Institute in Cambridge, Massachusetts, US, have now found that adult stem cells in bone marrow gradually lose their ability to regenerate without their normal complement of membrane - bound prions.
Exomeres largely fuse with cells in the bone marrow and liver, where they can alter immune function and metabolism of drugs.
In the COBRE for Stem Cell Biology, Brown and Rhode Island Hospital researcher Dr. Jason Aliotta is studying the role, for better and for worse, of different extracellular vesicles — blobs of material shed by cells — in mediating the production of harmful cells in bone marrow.
The diagnosis of multiple myeloma is made by the presence of elevated abnormal plasma cells in the bone marrow.
Quyyumi says the research team checked whether patients» pre-existing levels of CD34 + cells in their bone marrow had a significant effect on their outcomes; they did not.
The percentage of donor - derived hematopoietic cells in bone marrow cells of recipient tolerant mice was monitored using flow cytometry.
We also analyzed the hematopoietic stem cells and various progenitor cells in the bone marrow.
Dogs are correlated with different forms of leukemia disease, i.e. acute and chronic.The size of the population of white blood cells in the bone marrow represents the acuteness of disease.
If vaccines can have the same effect in dogs and a dog gets sick because of vaccine - induced mutations in cells in its bone marrow, liver or lungs it will not pass those mutations on to its offspring.
All three mouse models showed severe osteoporosis with accumulation of fat cells in the bone marrow, a pathology that resembles aged bone from enhanced adipocyte creation.
People in an acute stage of the disease often develop severe anemia, because the leukemia cells, which live almost ten times as long as their normal counterparts, replace healthy cells in the bone marrow.
Feline Panleukopenia Virus (FPV), after entering into the body, destroys dividing cells in the bone marrow, lymph tissues, epithelium (outer layer) of the intestine etc, thus severely depriving the immune system of the body.
Researchers can now tag individual malignant cells in the bone marrow of patients with acute myeloid leukemia.
The CLPs differentiate finally into T helper, T cytotoxic and T regulatory cells after leaving the bone marrow to the thymus or into mature B cells in the bone marrow.
Chronic (CLL)- Cancer cells in the bone marrow are a mix of normal and cancerous cells.
With amyloidosis, cells in the bone marrow produce antibodies that can not be broken down.
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