Chen and his team began by studying how reactive glial cells respond to a specific protein, NeuroD1, which is known to be important in the formation of
nerve cells in the hippocampus area of adult brains.
She showed that neural
stem cells in the hippocampus of mice genetically modified to mimic Alzheimer's symptoms develop abnormally and integrate poorly into the network of neural circuits.
Using a miniature microscope inserted into the brains of the mice, Hen's team recorded the activity of hundreds of
cells in the hippocampus as the mice freely moved around their surroundings.
In a famous set of experiments in human subjects in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston activated a single brain
cell in the hippocampus region — the so - called Jennifer Aniston neuron.
Now with the ability to compare these two populations, the team found that
chandelier cells in the hippocampus expand twice the size of axonal arbors in the neocortex and made twice as many connections as their counterparts.
A month after H7N7 or H3N2 infection, mice had fewer nerve cell connectors called dendritic spines
on cells in the hippocampus, a brain region involved in memory.
Turmeric Produces «Remarkable» Recovery in Alzheimer's Patients > In another experiment researchers successfully used flashes of blue light to
stimulate cells in the hippocampus region, encouraging the growth of neural pathways in this area of brain >.
NEW ROLE A kind of brain cell called an astrocyte (shown) may help nerve
cells in the hippocampus form traumatic memories, a study in rats suggests.
«Tsao's work provides the first specific hypothesis for how the response of face cells in the cortex can be utilised
by cells in the hippocampus to form memories of individuals we've seen before,» says Ueli Rutishauser at the Cedars - Sinai Medical Center in Los Angeles.
Both the healthy mice and the mice without Narp had three times the number of new
cells in the hippocampus after ECT than the mice that were given the sham procedure.
It was already known that a few weeks after an ECT procedure or after taking an effective antidepressant that stem
cells in the hippocampus turn on and make more copies of hippocampal neurons.
In addition, the Honeycomb Maze enables researchers to study the correlation of spatial navigation performance with the activity of place
cells in the hippocampus where there is a map of an animal's location in space.
Buried deep underneath the folds of the cerebral cortex, neural stem
cells in the hippocampus continue to generate new neurons, inciting a struggle between new and old as the new attempts to gain a foothold in memory - forming center of the brain.
To find out if these chemical changes do indeed take place, the researchers first identified a group of
engram cells in the hippocampus that, when activated using optogenetic tools, were able to express a memory.
In his lab, Sejnowski's team uses sophisticated electrical and chemical monitoring techniques to measure changes that occur in the connections among nerve
cells in the hippocampus during a simple form of learning.
The discovery of
anxiety cells in the hippocampus of the brain could pave way for new drugs that can better address the most common mental illness in the United States.
Stress - activated cortisol bombards the memory center, killing
nerve cells in the hippocampus, and attacks the immune system, which often causes depression and anxiety.
The prize is for discovering «the brain's navigation system»: place cells,
cells in the hippocampus which are active whenever a rat is in a particular place, and grid cells, cells in the entorhinal cortex which are active when the animal is at multiple locations in a grid pattern.
To answer this question of nature versus nurture, the researchers took cells that would grow to become
chandelier cells in the hippocampus and transplanted them into the neocortex, and took cells that would grow to become neocortical chandelier cells and transplanted them to the hippocampus.
Using a miniature microscope inserted into the brains of the mice, the researchers recorded the activity of hundreds of
cells in the hippocampus as the mice freely moved around their surroundings.
Close to the postrhinal - entorhinal border, entorhinal neurons had stable and discrete multipeaked place fields, predicting the rat's location as accurately as
place cells in the hippocampus.
She said numerous studies have shown that exercise has benefits for brain cell health, including the growth of
new cells in the hippocampus, the brain's memory center.
Howard Eichenbaum, director of the Center for Memory and Brain at Boston University, has been studying the function of «time»
cells in the hippocampus of mice.
When rats experience trauma,
cells in the hippocampus — an area important for learning — produce signals for inflammation, helping to create a potent memory.
The recordings revealed that, as the rats ran along each track,
the cells in their hippocampus would fire in a particular sequence.
Previous studies have shown that the ability of adult mice to grow new nerve
cells in the hippocampus can be influenced by genetic background, Gage says, suggesting that this ability may vary widely across species.
«Because the structure we detected was similar in all three experimental conditions, we think that we are picking up the fundamental organization of place
cells in the hippocampus,» said Itskov.
Further studies showed that THC boosted the number of connections between brain
cells in the hippocampus, which is involved in memory formation.
«Now that we've found
these cells in the hippocampus, it opens up new areas for exploring treatment ideas that we didn't know existed before,» says the study's lead author Jessica Jimenez, PhD, an MD / PhD student at Columbia University's Vagelos College of Physicians & Surgeons.
«We were able to demonstrate for the first time that these specific cells — a small group of
cells in the hippocampus — had undergone this augmentation of synaptic strength,» Tonegawa says.
O'KEEFE: I'd have to say there was quite a bit of skepticism on several grounds when we first started reporting that we could show very specific correlates to the activity of
cells in the hippocampus, and specifically, that they were related to where the animal was in the environment.
The discovery of the gatekeeper cells, which are part of a memory network together with several other nerve
cells in the hippocampus, reveal new fundamental knowledge about learning and memory.
«Now that we've found
these cells in the hippocampus, it opens up new areas for exploring treatment ideas that we didn't know existed before,» said the study's lead author, Jessica Jimenez, an MD / PhD student at Columbia University's Vagelos College of Physicians & Surgeons.
«Now that we've found
these cells in the hippocampus, it opens up new areas for exploring treatment ideas that we didn't know existed before,» says lead author Jessica Jimenez of Columbia University.