Sentences with phrase «cell interior»

«If Ltn1p is not active in pathologically modified cells or if other components of quality control are missing, defective proteins accumulate and form aggregates in cell interiors,» says Park.

The darkest regions with the least amount of magnetic flux correspond to the faint supergranule cell interior (component A).

Amy Elkins, Sketch of a death row cell interior by a then 23 year old man who has been serving time on death row for over 13 years, 2010, 11 x 14 inch archival pigment print.

The new active ingredient consists of DARPins (red and orange) bend the HER2 receptors (blue) so no more growth signal is transmitted into the cell interior (below the cell membrane in yellow).

This «receptor bending» prevents any growth signals from being transmitted into the cell interior, and the cancer cells die off.

While investigating mitochondria in nematodes genetically engineered to have Huntington's disease, Dillin and his colleagues discovered that the abnormal proteins actually aggregate on the mitochondria, and that this ramps up the protein folding response within the cell, flooding both the mitochrondria and the cell interior with nearly 100 types of so - called heat shock proteins to try to fix the misfolded proteins.

Chemical mediators, which ferry electrons back and forth between the cell interior and the electrode, can do the trick, but they tend to be expensive and inefficient, and require frequent replenishing.

«We do not know yet how the shares of measured glucose are distributed between vessels and extracellular spaces on the one hand and the cell interior on the other,» said radiologist Heinz - Peter Schlemmer.

«If we can confirm that substantial signal levels originate from glucose in the cell interior, this would be important additional information for tumor imaging and functional MRI.

«We developed an innovative method based on single - molecule microscopy, which allowed us for the first time to visualize individual receptors and G proteins at work on the surface of living cells and to directly investigate how they meet and interact to transduce the signal to the cell interior.

The team has succeeded not only in deciphering what is happening in the cell interior but also, using a revolutionary live - cell microscopy technique, the scientists have observed for the first time individual receptors at work in intact cells.

This belief has been shaken by a series of recent studies, which have suggested that GPCRs are also active in the cell interior.

They were following up on test tube studies showing that PTP - 1B removes certain phosphates from the receptor that transmits insulin signals to the cell interior (type 2 diabetes is thought to result from an inability to respond to insulin).

Professor Davide Calebiro, of the Institute of Metabolism and Systems Research at the University of Birmingham and of the Institute of Pharmacology at the University of Wuerzburg (Germany), said: «GPCRs transmit their signals to the cell interior via interacting with G proteins.

They convey information about a cell's environment to the cell interior.

This involved the movement through the cell interior of vesicles similar in appearance to those of neurons and their fusion with the plasma membrane — which Rothman described as being like «the coalescence of two soap bubbles» — and emptying of their contents.

This alkaline level promotes health because enzymes perform at optimum efficiency in the cells at this pH. Water washes out the acidity of the cell and makes the cell interior alkaline.

Senior editor Joe Lorio added, «Infiniti is officially the master of the padded - cell interior.

The four main components of the quiet Sun (Vernazza et al. 1981; Fontenla et al. 1999) are: component A (faint supergranule cell interior), component C (average supergranule cell interior), component E (average network or quiet network), and component F (bright network).