Sentences with phrase «cell leukemia whose»
Inspired by XBP - 1's roles in maintaining a homeostatic ER, the lab began to examine the role of XBP - 1 in B - cell leukemia whose progression does not require dramatic ER expansion like that in multiple myeloma.
https://wistar.org/ Not exact matches
By creating an experimental model of leukemia in mice whose cancer cells were resistant to chemotherapy the team was able to caracterize these cells» metabolic profile and observed certain modifications at the level of the mitochondria.
Park and colleagues genetically engineered T cells from 51 people whose leukemia came back or who didn't respond to initial chemotherapy.
«CD22 CAR T - cell immunotherapy trial open for children and young adults whose leukemia escapes CD19 CAR T - cell therapy.»
«These findings could lead to a new therapeutic strategy for patients with AML and potentially other diseases by targeting patients whose leukemia cells display activation of a specific survival pathway.»
In addition to being integral to cell biology, tyrosine kinases also present targets for new anticancer therapies: One of the most highly touted, rationally designed anticancer compounds, Gleevec, inhibits an oncogenic tyrosine kinase whose aberrant activity fuels the rampant growth of cells in patients with chronic myeloid leukemia.
By developing a CAR T - cell therapy that targets a second target on malignant cells, it may help leukemia patients whose cancer cells lack the C19 molecule or lose it.