Sentences with phrase «cell leukemias remain»

Not exact matches

Furthermore, while the approach has shown tremendous promise in treating blood - based cancers like leukemia, solid tumors remain stubbornly difficult to treat with CAR T cells.

These donor cells also help fight off any remaining leukemia cells, a phenomenon known as the graft - versus - leukemia (GVL) effect.

«While it has been previously shown that ATRA's ability to degrade the leukemia - causing fusion oncogene PML - RAR causes ATRA to stop the leukemia stem cells that drive APL, the underlying mechanism has remained elusive,» says Lu.

Acute myeloid leukemia (AML) is the leading cause of leukemia mortality in the United States.1 Curative treatment involves intensive induction chemotherapy, before proceeding to either consolidation chemotherapy or allogeneic stem cell transplantation based on the patient's risk for relapse.2 This approach has been employed for > 4 decades and, although most individuals achieve complete remissions with front - line therapy, 3 the majority of patients ultimately relapse with drug - resistant disease, and overall survival rates remain disappointingly poor.4 The limited ability of many patients to tolerate the intense chemotherapy - based treatments, in particular hematological toxicity, further contributes to the poor outcomes noted in this disease.

Chemotherapy can never kill off all a person's leukemia cells, so this sort of immunotherapy is important to teach the immune system to find and attack those remaining blood cancer cells, Greer said.

Many times dogs with chronic leukemia have regular red blood cell and platelet counts, and they remain fairly healthy without treatment.