Sentences with phrase «cell level after»

1994 saw her as Head of the Department of Transplantation Immunology at the CLB, in Amsterdam, and in 1999 she became Head of the department of the Immunology of the Laboratory of Vaccine Research of the National Institute of Public Health and Environmental Protection (RIVM), in Bilthoven, where her research activities focused on defining immunological correlates of protection on the T and B cell level after natural infection and vaccination.
No observed local immunological response at cell level after five years of oats in adult coeliac disease.

Not exact matches

Lentils are high in fiber that can help to stabilize blood sugar levels and a fantastic source of protein to repair cells after a workout.
White blood cell levels are elevated after birth, but slowly fall as time goes on.
After a few high doses of immune - boosting milk, the levels of white blood cells drop down to about two percent.
It is possible that stimulating these cells artificially after menopause, when natural estrogen levels drop, could contribute to breast cancer.
After EZH2 enzymes rise, their levels taper off, and then, the scientists found two to three-fold increases in a protein called DNMT1, which maintains DNA methylation in the «start» location of a variety of tumor suppressor genes that normally suppress cell growth.
The textbooks will tell you that oxygen levels began climbing soon after photosynthesis evolved, but we now know that some cells started photosynthesising as long as 3.4 billion years ago, long before oxygen levels began to rise.
A new study has identified a group of molecules in prostate - cancer cells that doctors might one day use to distinguish which patients should be treated with radiation therapy if rising PSA levels indicate their cancer has recurred after surgical removal of the prostate.
After it converts ATP to ADP, the level of the latter accumulates outside the cell and the purine can bind to a purine receptor called P2Y1.
When O'Malley's team exposed female rats to estrogen and progesterone to mimic pregnancy, the animals maintained high levels of p53 in their breast cells long after the hormone treatment ended.
The contest ends after a week; at that time, Clavería predicts, surviving cells produce uniform (and higher) levels of Myc.
The findings suggest that damage to brain cells called interneurons disrupts neurotransmitter levels and plays a role in the development of epilepsy after a traumatic brain injury.
They found that after 180 days neither dose led to measurable changes in the soil's mix of DNA and molecules found in bacterial cell walls (which reveals the amount and types of bacteria present), its levels of nutrients or rate of CO2 formation — the latter of which reflects how well the bacteria are utilizing oxygen.
The fact that insulin levels go up after a meal indicates these remaining beta cells can respond to a meal in the normal way — it seems they are either immune to attack, or they are regenerating.
When levels of arbitrium build up — after a large number of cells have died — phages stop killing off the remaining bacteria and retreat to lie dormant in bacterial genomes instead.
Two months after therapy, tissue analysis showed less scarring and higher levels of regenerative agents such as fibroblast growth factor — which accelerate healing — in rats treated with SIS plus stem cells compared with those treated with SIS alone.
Cells in the pancreatic islets called beta cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a Cells in the pancreatic islets called beta cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a meal.
But like Bandelow, he isn't sure of XBD173's long - term effects — particularly in cells such as the testes and adrenal glands that boast very high levels of the protein the new drug goes after.
But the researchers discovered that after an overdose, liver cells turn on a gene that shuttles desperately - needed cysteine into the cell but pumps glutamate out, until eventually glutamate levels start to run low, too.
They found that infection of the narrowest airways of the lung by PIV3 alone caused moderate levels of inflammation, but after infection by PIV3 expressing RSV NS2, the epithelial cells lining the narrow airways were shed rapidly into the airway lumen.
Ali found that breast cancer cells that have high levels of RYBP are more sensitive to DNA damage after radiation or drug treatment, including PARP inhibitors (inhibitors of the enzyme poly ADP ribose polymerase used in cancer treatment).
After five months, levels of the T cells declined in treated patients.
While most enzymes remain active only as long as their activators are bound, Stivers» group found that SAMHD1 remains active for about half a day after its activators have fallen off, enabling the enzyme to get cellular nucleotides to really low levels that make it almost impossible for HIV to infect cells.
The UNC researchers showed that increasing the level of p53 in scar - forming cells significantly reduced scarring and improved heart function after heart attack.
After 10 days of age, the manipulations reduced the distance flies could climb up tubes and the alterations caused older flies to have signs of neurodegeneration, including higher than normal levels of brain cell death and degradation.
The authors highlight an intriguing finding, which was that the level of antibody tinkering — known as somatic hypermutation — did not increase in volunteers» B cells over time after seasonal flu immunization.
However, levels of the infused cells began to steadily decline after the two - week mark, and became undetectable after one month.
After they gave birth, she measured the levels and types of immune cells in both the mothers» blood and the babies» umbilical cord blood.
«Our finding suggests that a factor may exist which determines the characteristic speed of a cell and that factor is set at random levels in the new cells after cell division.»
Shortly after sex, the cervix releases immune signalling molecules, which may be an early sign of increasing levels of regulatory T - cells.
But an even more surprising observation was that the cells didn't go away — they hung around at a 10-fold increase over prepregnancy levels for more than 100 days after birth (the equivalent of 4 years to 5 years in humans).
Regarding the mechanisms, they say «the delayed antibody and germinal center cell responses are due to trafficking defects, which are compounded by lower levels of chemokines in the lymph node after infection.
Immediately after the subjects viewed the slide shows, researchers drew their blood, exposed each sample to bacteria and then measured the levels of a substance known as interleukin - 6 (IL - 6), which is secreted by white blood cells as a response to stress or trauma.
Retinal ganglion cells only began to die after they're affected by high levels of zinc leaking from injured amacrine cells.4
Throughout the day, the pancreas regulates the body's blood sugar levels, responding to an increase in glucose after a meal by secreting insulin, which helps cells take up the sugar.
The current study found that mice meant to serve as a model of ischemic human heart failure (weaker blood flow after a heart attack) had higher levels of activated, pro-inflammatory macrophages, monocytes, dendritic cells and T cells trafficking between their hearts and spleens than did control mice with healthy hearts.
Four weeks after transplanting these cells into the kidney cavities of mice with a form of kidney anaemia, the treated animals had blood EPO levels 20 times higher than those in controls (Science Translational Medicine, doi.org/cdmx).
Shortly after infection, HIV levels skyrocket, but then the immune system and other antiviral factors produced by cells drive down the amount of virus in the blood — the so - called viral load — and establish a «set point.»
Further experiments identified new therapeutic options: Mice that are unable to produce Type - 1 interferon were protected against Listeria infection despite the migration of the gut bacteria into the liver, because their immune cells didn't produce high levels of Type - 1 interferon and IL - 10 after Listeria infection.
Mice that lacked a specific protein from the complement system had lower levels of the parasite in their red blood cells after being infected.
MAIT cells are also activated by and kill epithelial cells expressing endogenous levels of MRI after infection with the invasive bacteria Shigella flexneri.
Hirano, Egli and colleagues have shown that in unusual cases, stem cell clones derived from MR eggs can show substantial drift towards the donors mtDNA haplotype after low level mtDNA carryover during the MR procedure.
The exception was one cell line, out of 5, where the mitochondrial DNA type associated with the transferred pronuclei increased over time to much higher levels than present in the embryo after PNT.
After addition of exogenous IL - 2, the levels of IFN - γ production in culture media of stimulated CD8 + T cells increased in all genotypes, again likely attributable to cell number (Fig. 3F).
Cyclin D1 - levels varying throughout cell cycle, hence its expression in G1 phase increases in the cell that respond to enter a new cycle after receiving growth factor stimulation [8].
The pharmacokinetic properties of J147 after a single dose of 20 mg / kg in mice show brain levels of about 600 nM at 2 h, over 10-fold above its EC50 in some cell culture neuroprotection assays [7], with a brain to blood ratio of approximately 0.5.
After 48 hours of transfection, cell extracts were prepared and the expression level of FLAG - DDX3, p21waf1 / cip1, and α - actin was detected by immunoblotting with anti-FLAG, anti-p21waf1 / cip1, and anti-α-actin (Santa Cruz Biotechnology, Santa Cruz, CA) antibodies.
We've known for a little while that drugs that interfere with mTOR decrease levels of mutant huntingtin protein by helping cells destroy it after it's made.
Therefore, we also examined MKK3 and MKK6 levels in MNK - 3 cells after lethal toxin treatment.
a b c d e f g h i j k l m n o p q r s t u v w x y z