1994 saw her as Head of the Department of Transplantation Immunology at the CLB, in Amsterdam, and in 1999 she became Head of the department of the Immunology of the Laboratory of Vaccine Research of the National Institute of Public Health and Environmental Protection (RIVM), in Bilthoven, where her research activities focused on defining immunological correlates of protection on the T and B
cell level after natural infection and vaccination.
No observed local immunological response at
cell level after five years of oats in adult coeliac disease.
Not exact matches
Lentils are high in fiber that can help to stabilize blood sugar
levels and a fantastic source of protein to repair
cells after a workout.
White blood
cell levels are elevated
after birth, but slowly fall as time goes on.
After a few high doses of immune - boosting milk, the
levels of white blood
cells drop down to about two percent.
It is possible that stimulating these
cells artificially
after menopause, when natural estrogen
levels drop, could contribute to breast cancer.
After EZH2 enzymes rise, their
levels taper off, and then, the scientists found two to three-fold increases in a protein called DNMT1, which maintains DNA methylation in the «start» location of a variety of tumor suppressor genes that normally suppress
cell growth.
The textbooks will tell you that oxygen
levels began climbing soon
after photosynthesis evolved, but we now know that some
cells started photosynthesising as long as 3.4 billion years ago, long before oxygen
levels began to rise.
A new study has identified a group of molecules in prostate - cancer
cells that doctors might one day use to distinguish which patients should be treated with radiation therapy if rising PSA
levels indicate their cancer has recurred
after surgical removal of the prostate.
After it converts ATP to ADP, the
level of the latter accumulates outside the
cell and the purine can bind to a purine receptor called P2Y1.
When O'Malley's team exposed female rats to estrogen and progesterone to mimic pregnancy, the animals maintained high
levels of p53 in their breast
cells long
after the hormone treatment ended.
The contest ends
after a week; at that time, Clavería predicts, surviving
cells produce uniform (and higher)
levels of Myc.
The findings suggest that damage to brain
cells called interneurons disrupts neurotransmitter
levels and plays a role in the development of epilepsy
after a traumatic brain injury.
They found that
after 180 days neither dose led to measurable changes in the soil's mix of DNA and molecules found in bacterial
cell walls (which reveals the amount and types of bacteria present), its
levels of nutrients or rate of CO2 formation — the latter of which reflects how well the bacteria are utilizing oxygen.
The fact that insulin
levels go up
after a meal indicates these remaining beta
cells can respond to a meal in the normal way — it seems they are either immune to attack, or they are regenerating.
When
levels of arbitrium build up —
after a large number of
cells have died — phages stop killing off the remaining bacteria and retreat to lie dormant in bacterial genomes instead.
Two months
after therapy, tissue analysis showed less scarring and higher
levels of regenerative agents such as fibroblast growth factor — which accelerate healing — in rats treated with SIS plus stem
cells compared with those treated with SIS alone.
Cells in the pancreatic islets called beta cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a
Cells in the pancreatic islets called beta
cells are responsible for modulating the body's response to the rise and fall of blood glucose levels after a
cells are responsible for modulating the body's response to the rise and fall of blood glucose
levels after a meal.
But like Bandelow, he isn't sure of XBD173's long - term effects — particularly in
cells such as the testes and adrenal glands that boast very high
levels of the protein the new drug goes
after.
But the researchers discovered that
after an overdose, liver
cells turn on a gene that shuttles desperately - needed cysteine into the
cell but pumps glutamate out, until eventually glutamate
levels start to run low, too.
They found that infection of the narrowest airways of the lung by PIV3 alone caused moderate
levels of inflammation, but
after infection by PIV3 expressing RSV NS2, the epithelial
cells lining the narrow airways were shed rapidly into the airway lumen.
Ali found that breast cancer
cells that have high
levels of RYBP are more sensitive to DNA damage
after radiation or drug treatment, including PARP inhibitors (inhibitors of the enzyme poly ADP ribose polymerase used in cancer treatment).
After five months,
levels of the T
cells declined in treated patients.
While most enzymes remain active only as long as their activators are bound, Stivers» group found that SAMHD1 remains active for about half a day
after its activators have fallen off, enabling the enzyme to get cellular nucleotides to really low
levels that make it almost impossible for HIV to infect
cells.
The UNC researchers showed that increasing the
level of p53 in scar - forming
cells significantly reduced scarring and improved heart function
after heart attack.
After 10 days of age, the manipulations reduced the distance flies could climb up tubes and the alterations caused older flies to have signs of neurodegeneration, including higher than normal
levels of brain
cell death and degradation.
The authors highlight an intriguing finding, which was that the
level of antibody tinkering — known as somatic hypermutation — did not increase in volunteers» B
cells over time
after seasonal flu immunization.
However,
levels of the infused
cells began to steadily decline
after the two - week mark, and became undetectable
after one month.
After they gave birth, she measured the
levels and types of immune
cells in both the mothers» blood and the babies» umbilical cord blood.
«Our finding suggests that a factor may exist which determines the characteristic speed of a
cell and that factor is set at random
levels in the new
cells after cell division.»
Shortly
after sex, the cervix releases immune signalling molecules, which may be an early sign of increasing
levels of regulatory T -
cells.
But an even more surprising observation was that the
cells didn't go away — they hung around at a 10-fold increase over prepregnancy
levels for more than 100 days
after birth (the equivalent of 4 years to 5 years in humans).
Regarding the mechanisms, they say «the delayed antibody and germinal center
cell responses are due to trafficking defects, which are compounded by lower
levels of chemokines in the lymph node
after infection.
Immediately
after the subjects viewed the slide shows, researchers drew their blood, exposed each sample to bacteria and then measured the
levels of a substance known as interleukin - 6 (IL - 6), which is secreted by white blood
cells as a response to stress or trauma.
Retinal ganglion
cells only began to die
after they're affected by high
levels of zinc leaking from injured amacrine
cells.4
Throughout the day, the pancreas regulates the body's blood sugar
levels, responding to an increase in glucose
after a meal by secreting insulin, which helps
cells take up the sugar.
The current study found that mice meant to serve as a model of ischemic human heart failure (weaker blood flow
after a heart attack) had higher
levels of activated, pro-inflammatory macrophages, monocytes, dendritic
cells and T
cells trafficking between their hearts and spleens than did control mice with healthy hearts.
Four weeks
after transplanting these
cells into the kidney cavities of mice with a form of kidney anaemia, the treated animals had blood EPO
levels 20 times higher than those in controls (Science Translational Medicine, doi.org/cdmx).
Shortly
after infection, HIV
levels skyrocket, but then the immune system and other antiviral factors produced by
cells drive down the amount of virus in the blood — the so - called viral load — and establish a «set point.»
Further experiments identified new therapeutic options: Mice that are unable to produce Type - 1 interferon were protected against Listeria infection despite the migration of the gut bacteria into the liver, because their immune
cells didn't produce high
levels of Type - 1 interferon and IL - 10
after Listeria infection.
Mice that lacked a specific protein from the complement system had lower
levels of the parasite in their red blood
cells after being infected.
MAIT
cells are also activated by and kill epithelial
cells expressing endogenous
levels of MRI
after infection with the invasive bacteria Shigella flexneri.
Hirano, Egli and colleagues have shown that in unusual cases, stem
cell clones derived from MR eggs can show substantial drift towards the donors mtDNA haplotype
after low
level mtDNA carryover during the MR procedure.
The exception was one
cell line, out of 5, where the mitochondrial DNA type associated with the transferred pronuclei increased over time to much higher
levels than present in the embryo
after PNT.
After addition of exogenous IL - 2, the
levels of IFN - γ production in culture media of stimulated CD8 + T
cells increased in all genotypes, again likely attributable to
cell number (Fig. 3F).
Cyclin D1 -
levels varying throughout
cell cycle, hence its expression in G1 phase increases in the
cell that respond to enter a new cycle
after receiving growth factor stimulation [8].
The pharmacokinetic properties of J147
after a single dose of 20 mg / kg in mice show brain
levels of about 600 nM at 2 h, over 10-fold above its EC50 in some
cell culture neuroprotection assays [7], with a brain to blood ratio of approximately 0.5.
After 48 hours of transfection,
cell extracts were prepared and the expression
level of FLAG - DDX3, p21waf1 / cip1, and α - actin was detected by immunoblotting with anti-FLAG, anti-p21waf1 / cip1, and anti-α-actin (Santa Cruz Biotechnology, Santa Cruz, CA) antibodies.
We've known for a little while that drugs that interfere with mTOR decrease
levels of mutant huntingtin protein by helping
cells destroy it
after it's made.
Therefore, we also examined MKK3 and MKK6
levels in MNK - 3
cells after lethal toxin treatment.