Sentences with phrase «cell levels during»

Researchers also monitored prostate cancer risk, based on prostate - specific antigen levels and a rectal exam, and stroke risk, based on red blood cell levels during the treatment year and for at least a year afterward.

Not exact matches

Some of my favorite variations include a citrus fruit such as grapefruit, lime or lemon for its refreshing taste, carrots for their high levels of beta - Carotene, or pineapple for the high concentration of vitamin C and manganese, essential during the energy production process within our cells.

This study showed that mtDNA levels are higher in the surviving cholinergic neurons of the brainstem, but with both cell - types that undergo profound degeneration during Parkinson's disease.

«Despite the low infection levels of mouse cells with oHSV, we were able to cause a delay in tumor growth in one of the cancer models and even cure many of the mice in a second model,» said first author Jennifer Leddon, who conducted much of the laboratory work during a research experience in the Center for Childhood Cancer and Blood Diseases.

Using X-ray beams and lasers, researchers studied how a new promising class of solar cell materials, called hybrid perovskites, behaves at the nanoscale level during operation.

In the study, human melanocytes — the cells that produce the skin pigment melanin — were exposed to estrogen levels usually seen during pregnancy.

To assess potential mast cell involvement in vibratory urticaria, the researchers measured blood levels of histamine during an episode of vibration - induced hives.

Their work on the fruit fly revealed brief surges in calcium levels in the cell nuclei of certain neurons during learning.

Looking for the presence of chemicals commonly seen during inflammation and cell death, the researchers noticed abnormally high levels of RIPK1 — a known promoter of cell death — in spinal cord cells from mice lacking OPTN.

One of the chemicals found in high levels in the blood of people experiencing migraine is calcitonin gene - related peptide (CGRP), a neurotransmitter that is released from one nerve cell and activates the next one in a nerve tract during an attack.

The new findings and the fact that patients with sickle cell disease have significant variability in their nitric oxide levels — even during a pain crisis — likely explains why, Ikuta said.

«While several lipid families are well - characterized at the molecular level, the total diversity and number of unique lipids in cells, how they change during cellular activation, and how they differ in individuals is unknown,» said Darley - Usmar.

During aging, the levels of stem cell division and formation of new neurons decrease.

If the mouse became pregnant a second time during this window, the number of T cells grew more rapidly — and reached higher levels — than the first time, conferring extra protection to the fetus.

Through studies conducted in mice, Oliver M. Steinmetz, MD (University Hospital Hamburg Eppendorf, in Germany) and his colleagues have shown that the messenger protein IL - 6, which is rapidly produced at high levels during an acute inflammatory form of kidney disease, potently dampens activation of tissue - destructive immune cells called macrophages.

In Cell Metabolism on August 13, the Harvard scientists who discovered irisin address this contentious issue by showing that human irisin circulates in the blood at nanogram levels and increases during exercise.

When the researchers looked at the molecular details of the PER1 protein, they found that the mutated PER1 led to lower protein levels during the sleeping period, higher levels during the waking period, and a faster degradation of protein whenever it was produced by cells.

During pregnancy, the elevated blood estrogen level induces the proliferation of mammary epithelial cells, leading to the development of the mammary gland in preparation for lactation.

They assessed gene activity at time points known to correspond with key phases of disease: the «induction phase,» the time before the peak level of photoreceptor cell death; the «execution phase,» when the highest rates of photoreceptor cell death occur; and the «chronic phase,» during which photoreceptor cell death continues at somewhat reduced levels.

Conrad Hal Waddington coined a classical metaphor for the process of cell differentiation during development: An epigenetic landscape characterized by valleys of different levels, and hills to separate them.

Hirano, Egli and colleagues have shown that in unusual cases, stem cell clones derived from MR eggs can show substantial drift towards the donors mtDNA haplotype after low level mtDNA carryover during the MR procedure.

Perhaps during normal inflorescence development, SMs poised to become bristles accumulate higher levels of BR, resulting in local increased cell division and expansion, loss of boundary identity genes, and repression of the SM identity program.

These elusive, as yet undiscovered genes tend to be expressed at low levels or only in certain cell types, or turned on only during specific developmental stages or growth conditions.

During this Cell Symposium, we will delve into the fascinating mechanistic and physiological complexities of exercise biology at the cellular, tissue, and systemic levels and explore how exercise improves human health, including in disease settings and during During this Cell Symposium, we will delve into the fascinating mechanistic and physiological complexities of exercise biology at the cellular, tissue, and systemic levels and explore how exercise improves human health, including in disease settings and during during aging.

The levels of mC are altered in cancer cells and during the development of embryos.

In a previous study, it was found that compared with women carrying a female fetus, women with a male fetus had decreased β - cell capacity and higher postprandial glucose levels during glucose challenge (89).

These cells secrete high levels of interleukin - 22 (IL - 22), a key cytokine for maintaining barrier tissues during inflammation.

The group of promoters, whose H3K4me3 levels were affected by combined chidamide and decitabine treatment, but not by either chidamide or decitabine treatment alone, was enriched with binding site motifs for PU.1, a transcription factor that activates gene expression during myeloid and B - cell lymphoid cell development15, 16 (Figure 5C).

Following the observation that levels of a protein called FoxO1 decrease in beta - cells during early diabetes, researchers created a strain of GM mouse whose beta - cells lack the FoxO1 gene.

For a systems - level understanding of all crucial protein interactions during cell division, we are combining automated single molecule calibrated imaging and computational data analysis with advanced machine learning and modelling approaches to build an integrated protein atlas of the human dividing cell.

Multiple levels of tobacco WIPK activation during the induction of cell death by fungal elicitins

They went on to show that Sox10, a factor needed for the formation of skin pigment cells from neural crest stem cells during development, was present at high levels in naevi and melanoma samples obtained from both the mouse model and human patients.

Adding to the complexity of this disease, people with T1D also have dysfunctional alpha cells that, during activities such as exercise, permit uncorrected and dangerously low glucose levels that can lead to unconsciousness or even death.

While imaging captures brain activation during specific tasks and therefore may identify general brain regions that are abnormal in diseases, it does not have that critical cell - level resolution.

In contrast, previous studies have shown that Oct4 mRNA levels can remain relatively stable during DMSO - induced differentiation of P19 cells, although this has been ascribed to undifferentiated, highly proliferative cells present in the cultures following differentiation [22], [34].

A. Average expression levels of Global Clusters 4, 12, 15, 20 and 30 that contain up regulated transcripts during ES cell differentiation.

While found in some mammary cells prior to pregnancy, the activated form of STAT5 is detected in the great majority of epithelial mammary cells, and at increased levels, during pregnancy and lactation (Liu et al., 1995; Wagner and Rui, 2008).

These data suggest that premalignant mammary cells respond to pregnancy and lactation hormones by activating STAT5, as their normal counterparts do (Figure 3A inset); however — unlike their normal counterparts — they continue to maintain high levels of pSTAT5 even during involution (Figure 3 — figure supplement 1B).

Focusing on these «soldier» cells during meditation can be effective on a cellular level.

It involves cell degradation of unnecessary or dysfunctional cellular components, which ensures cellular survival during starvation by maintaining cellular energy levels.

Lower insulin levels at rest will enable you to burn more fat, while elevated levels during the workout will enhance muscle growth by promoting rapid uptake of amino acids and glycogen into the muscle cells.

People with heart disease have high levels of CRP in their blood because it's released by cells during inflammation, the immune system's attempt to defend against disease or infection.

High levels of IGF - 1 during adulthood cause cancer cells to grow, people with genetic disorders producing minute quantities of IGF - 1 do not suffer from cancer, fact!

Used mostly during times of stress, L - Glutamine is a key ingredient for maintaining muscle and promoting cell regrowth while increasing energy levels and alertness.

Dr. Barnard's book helps with low - fat / no - fat plant foods that also have the lowest glycemic index to spread the absorption of the carbohydrates out over the longest possible time as a way of controlling blood sugar levels during the time the body is cleaning the fat out of the cells.

During the night, newly released hormones might increase your body's resistance to insulin, which ultimately impacts your body's ability to absorb sugar into the cells, resulting in high sugar levels in the blood.

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However, during times of disease, exercise, or environmental stress (e.g. smoking, sunlight or heat exposure) ROS levels can increase dramatically, which can result in significant damage to cell structures.

However, during times of disease, exercise, or environmental stress (e.g. smoking, UV or heat exposure) ROS levels can increase dramatically, which can result in significant damage to cell structures.

It is our speculation by maintaining high insulin sensitivity, when carbohydrates are brought back during competition the slight insulin response actually speeds delivery of glucose to cells and conversion of glucose to ATP without seriously impacting high level fat metabolism.