Sentences with phrase «cell lineage commitment»

Not exact matches

The second step will be to optimize culture conditions for the commitment of the iPS / hES cell - derived retinal precursors towards the photoreceptor lineage.

Differential expression of surface markers in mouse bone marrow mesenchymal stromal cell subpopulations with distinct lineage commitment.

Maria Rostovskaya (Stewart, TUD)-- «Lineage commitment of conditionally immortalized bone marrow mesenchymal stromal cells from tetracycline - regulated SV40 large t - antigen transgenic mice» (2010)

Altogether, these findings highlight the central role of Lkb1 during neural crest cell lineage and uncovered a link between Lkb1 - mediated pyruvate - alanine cycling and glial commitment.

Roberto Iacone (Anastassiadis, TUD)-- «Lineage commitment screens in mES cells using a tetracycline inducible cDNS library» (2009)

Title: Inferring rules of lineage commitment in haematopoiesis Authors: Pina C, Fugazza C, Tipping AJ, Brown J, Soneji S, Teles J, Peterson C, Enver T Date: 2012 Publication Details: Nature Cell Biology 2012 Feb 19; 14 (3): 287 - 294

Studying the epigenetic setting of germ cells allows investigating several crucial aspects of mammalian biology such as transposon control, genomic imprinting and early lineage commitment.

That this occurs once cells enter differentiation, is consistent with a requirement for sustained FGF signalling for commitment and segregation of the PrEn lineage in cultured blastocysts [57].

When the culture is removed from the constraints of self - renewal, lineage primed states drive commitment to a direction of differentiation based on the location of a cell in a specific state or attractor.

Concomitantly, epiblast cells transit through distinct pluripotent states, before lineage commitment at gastrulation.

Towards the center of the colony, ∼ 40 % of the cells had lost expression of all pluripotency markers, and we found a number of cells that were null - expressing no markers of pluripotency or lineage commitment, only the housekeeping gene cyclophilin a. However, many cells in this region still expressed Oct - 4.

Citation: Hough SR, Laslett AL, Grimmond SB, Kolle G, Pera MF (2009) A Continuum of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells.

Commitment in embryonic stem cells is often depicted as a binary choice between alternate cell states, pluripotency and specification to a particular germ layer or extraembryonic lineage.

The view of ES cell transcriptional regulation that emerges from these studies encompasses plasticity but nevertheless envisions lineage commitment and loss of pluripotency as an all or nothing switch.

Lineage commitment in the mammalian embryo is most often depicted as a series of binary choices between alternate cell states, and increasing evidence supports the hypothesis that fate decisions in embryonic stem (ES) cell cultures reflect these developmental processes [1].

These bivalent epigenetic marks are thought to prepare their cognate loci for transcription, in a cell that is poised to embark on lineage commitment.

Student, «Characterizing the macrophage response to peripheral nerve injury» Gat Rauner, Postdoc Assoc., «Cell Hierarchy, Lineage Commitment and Differentiation in the Bovine Mammary Gland» Lunch provided with sign up - please contact Sue Williams at [email protected] or 256-5600