Sentences with phrase «cell lines derived»

When we further characterized the cell lines derived from the iPSC - like colonies, we observed that they possessed hESC - like morphology, growing as flat colonies with large nucleo - cytoplasmic ratios, defined borders and prominent nucleoli (Figure 4C).

ES cells are defined as self - renewing, pluripotent cell lines derived from early embryos.

In the new study, the research team screened 16 DIPG cell lines derived from patients» tumors against 83 possible chemotherapy drugs, exposing cells to small samples of each drug.

The 19 hES cell lines derived in Strasbourg and banked at I - Stem are registered in the European Registry (hESCREG).

For this purpose, at least 30 different cell lines derived from biopsies (HNSCC — head and neck cancer — patients) wil be collected and grown in culture to esstablish cell lines.

More than 50,000 cell lines derived from patients are cryopreserved, representing an invaluable patrimony for the study of over 500 pathologies.

«Seven out of eight ES cell lines derived from (parthenogenetic) embryos after MRT (spindle transfer) showed no or very low persistence of the mtDNA haplotype that was carried over with the nuclear DNA.

Yes, it removed the Bush moratorium, but it only allows federal funding for new cell lines derived from embryos created for in vitro fertilization.

Novel cell lines derived from adult human ventricular cardiomyocytes.

The authors were led into the realm of muscle and sex when they realized that they were relying heavily on cell lines derived from female mice to study muscle regeneration.

His executive order allowed funding on embryonic stem - cell lines derived from embryos that had already been destroyed, but excluded funding of research using stem cells from embryos destroyed after August 9, 2001 (the date of his announced policy).

Such targets have recently been discovered in cell lines derived from aggressive childhood tumors using phenotypic profiling and RNAi screening.

Nonetheless, passage of the measure marks a significant milestone in efforts to overturn the Bush policy, which limits government funding to research using 60 human ES cell lines derived before 9 August, 2001.

We assayed from 6000 to 20,000 shRNAs simultaneously to identify genes important for the proliferation and survival of five cell lines derived from human mammary tissue.

WARF distributes stem cell lines derived by James Thompson, a researcher at the University of Wisconsin, Madison.

Palanichamy, Chakravarti and their colleagues conducted this study using 13 primary GBM cell lines derived from patient tumors, four commercially available GBM cell lines and normal human astrocyte cells.

Neural stem cell lines derived from human fetal brain tissue achieved the same feats, the researchers report in the October issue of Nature Neuroscience.

In four cell lines derived from human and monkey, siRNAs substantially lowered the expression of three of four test genes — by as much as 90 %.

A White House spokesperson said last night that stem cell lines derived after 9 August 2001 will not be eligible for NIH funding.

In addition, progesterone boosted expression of several of these genes in controls, while estrogen decreased expression in cell lines derived from PMDD patients.

«We set out to test this in cell lines derived from mice and humans, and came up with a result we definitely did not expect — which then led us to dig deeper for answers.»

The researchers tested honokiol on cell lines derived from human cancers of the oral cavity, larynx, tongue, and pharynx.

In lab experiments, the research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival of cells of high - grade serous ovarian cancer origin.

In addition to the afatinib - resistant NSCLC cells, the researchers tested the neratinib and valproic acid combination on cell lines derived from human pancreatic and ovarian cancers containing K - Ras mutations and N - Ras mutations, respectively.

CNIO's Bioinformatics Unit has been key in comparing 900 cell lines derived from up to 35 tumor types in order to identify unique aspects of melanoma.

The proposal would have waived an often - cumbersome permitting process for handling samples of everything from hair and DNA to cell lines derived from endangered species.

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

Cell lines derived 3 months or a year ago «should still be eligible for funding,» she argues.

In these instances, the committee says, the use of existing embryonic cell lines derived from embryos fewer than 14 days old should be considered before resorting to the use of cells taken from surplus in vitro fertilization embryos fewer than 14 days old.

He ruled that work on existing embryonic stem cell lines derived outside federally funded labs did not violate a ban on the destruction of embryos.

«Brain scientists have invented, established and patented a method to obtain long - living cell lines derived from fungiform taste papillae of the human tongue.

She added bacterial cells to a culture of a widely used mammalian cell line derived from the ovaries of Chinese hamsters.

In February 2004 Hwang and his research group reported the first embryonic stem cell line derived from a cloned human embryo.

Roein - Peikar also noted that their experiments are mainly based on Chinese Ovary Hamster cells, a cell line derived from the ovary of the Chinese hamster, often used in biological and medical research.

For the study published in Traffic, the researchers did not use pluripotent cells lines derived from Gulf War veterans, but said they plan to use veterans» cells in the future for more refined results.

HAT sensitive derivative of CEM, a human T - cell line derived from the peripheral blood buffy coat of a four - year old Caucasian female with acute lymphoblastic leaukemia.

ScienceDaily «A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis (PGD) to carry the mutation for fragile X syndrome has...

ES cells are an in vitro cell line derived from the inner cell mass (ICM) of the early mammalian blastocyst [1], [2].

BTI - Tnao38, a new cell line derived from Trichoplusia ni, is permissive for AcMNPV infection and produces high levels of recombinant proteins (vol 10, pg 50, 2010)

Not exact matches

Also, the NCM460 cell line that Dr. Ebert and the carrageenan lobby criticize is derived from normal colonic mucosa and is useful to model effects on colonic cells, in the same way that other intestinal cell lines, such as Caco2 and HT29, are useful.

Before we established in - house human taste cell (HTC) technologies, it was not possible to use human tongue - derived cells as a model, due to the lack of homogenous, proliferating cell lines with defined properties, which is a prerequisite to establish comprehensive research and screening programs.

That includes not only procedures in which embryonic - stem - cell lines are created, but also those that use previously derived cell lines.

To solve this, West proposed «therapeutic cloning» — taking the nucleus out of a patient's cell, transferring it into an egg cell to create a cloned embryo, then using that embryo to derive patient - matched stem - cell lines.

«By its own logic,» says Charo, Lamberth's ban on funding «should only apply to... cell lines that are being derived now.»

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

Where permitted, ES cells should be drawn from sources in the following order: (1) existing ES cell lines, originating from ES cells derived from embryos less than 14 days old; and (2) surplus human embryos less than 14 days old that were created for fertility treatment.

Another problem is that in its July 2009 Guidelines on Human Stem Cell Research, NIH spelled out specific requirements about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law School.

Svendsen injected into their brains a protein known to enhance neural development, called glial cell line - derived neurotrophic factor (GDNF).

Hamilton announced the newest organ - on - chip innovation, which recreates an intestinal lining using patient - derived stem cells, created through a partnership between Emulate and Cedars - Sinai Board of Governors Regenerative Medicine Institute.

Fact: The WI - 38 and MRC - 5 cell lines, derived from two fetuses that were aborted, respectively, in 1962 in Sweden and in 1966 in the United Kingdom, are used to produce the following vaccines, all licensed and marketed in the United States: