Sentences with phrase «cell lines responded»

«Whole - exome sequencing predicts which bladder cancers, cell lines respond to cisplatin.»

Not exact matches

The scientists further discovered that whenever food enters the bowels, cells in the intestinal lining immediately respond by increasing the production of ribosomes, particularly in the food - facing part of the cell.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

The current study just looked at cells of the epithelium, the layer of cells lining the gut, but there would be other cells responding to these microbial signals as well.

A Clinton cell, for example, would respond not only to various photos of the former president but also to a line drawing.

The cell responded to three very different images of the former president: a line drawing of Clinton laughing, a formal painting of him, and a photograph of him mingling with other dignitaries.

The possibility of such cells has been debated at least since the 1950s, when researchers found single neurons in the visual cortex of cats and other animals that respond to simple stimuli, such as lines oriented at a certain angle or moving in a specific direction, or light of a particular wavelength.

«By exposing human colonic organoids to inflammatory triggers, we can now learn how the cell lining of the colon and the supporting cells beneath cooperate to respond to inflammation,» Munera said.

The team found that cell lines appeared to respond to drugs in two broad patterns.

Lloyd A. Greene and Arthur S. Tischler of the Harvard Medical School demonstrated in 1977 that cells of the line designated PC12 (which are derived from a rat tumor) respond to NGF by acquiring properties characteristic of sympathetic neurons.

Until now, scientists examining the causes and effects of insulin resistance have struggled with a general lack of human cell lines from tissues such as muscle, fat and liver that respond significantly to insulin, Kahn says.

In analyses of the cell lines, precursor white fat cells from two subjects responded strongly to BMP7 but such cells from the other two subjects did not.

Understanding which cancer cell lines (and, by extension, which mutations) might respond to a specific compound or drug has profound implications for targeted therapy.

As a first line of defense against bacterial pathogens, plant cells recognize and respond to tiny bacterial molecules, such as pieces of flagellin that slough off the whip - like flagella that help the bacteria move.

So any DLBCL patient who is not responding to first - line chemotherapy or who has experienced a relapse should be referred to a center with expertise in CAR T - cell therapy.

Santa Monica women in Lexus RXs will beg you to slow down, because they can't hear you over the sound of their cell phones; you'll respond by ripping a start off the line because after all, talking while driving is dangerous and downright illegal — almost like driving a Jaguar F - Type, come to think of it.