Sentences with phrase «cell lining»

In the future, scientists may be able to modify human stem cell lines in the laboratory by using gene therapy or other techniques to overcome this immune rejection.

The drug resulted in greater than 80 percent decrease in growth of adrenal cancer cell lines as well as inhibition of tumor growth in animal models.

The group urged the creation of two central databases: One on stem cell lines in use worldwide and one on intellectual property rights so scientists can readily access information.

Recent studies highlighted significant differences between these two types of stem cells, although only a limited number of cell lines of different origins were analyzed.

The researchers are already developing stem cell lines from other trial participants with bipolar disorder, though it takes months to derive each line and obtain mature neurons that can be studied.

In the rare human cell line used for this genetic screen, the cells have only one copy of each chromosome, except for chromosome 8, which has two copies.

129 mice are widely used in the production of targeted mutations due to the availability of multiple embryonic stem cell lines derived from them.

Overall, making a human cell line with a gene knockout was straightforward, and is a testament to how far genome engineering has come.

As names are not even used consistently in publications and deviations from the original name are not rare, the situation increasingly causes confusion about the identity of cell lines used in specific studies.

An expansion of an ES cell clone is a minimal service and does not include verification of the identity of the ES cell line by DNA sequencing.

The authors were led into the realm of muscle and sex when they realized that they were relying heavily on cell lines derived from female mice to study muscle regeneration.

But researchers don't have efficient ways to compare the characteristics of different cell lines or to access lines that might be especially useful for a given project.

The authors studied a standard panel of 60 established human tumor cell lines representing nine different human cancers, as well as several specimens of human primary ovarian cancer.

Further, as people get older, their stem cells also tend to lose their ability to differentiate into new cell lines, including much - needed immune cells.

The researchers used a modified virus to insert genetic mutations into cells lining the mice's lungs, causing the animals to develop tumors.

It uses an established cell line that yields a vaccine with consistent potency.

It might work for small amounts of data, but not when you're talking about the equivalent of a DVD box set of data per cell line we require.

Overall they found that many of these risk genes are associated with the myriad of functions taking place in cells lining blood vessels.

This is essential to create and study disease - specific cell lines in a dish.

In particular, they open the possibility to study diseases for which there are no embryonic stem cell lines available.

Many other countries have since decided to allow research with these «existing cell lines».

All human cell lines growing in tissue culture dishes, and about 95 % of cells in a human being, split evenly, resulting in daughter cells of equal size.

Most of those findings came from studies in cell line models of diseases, however.

Our studies were performed using mouse and human immune cells and included cell lines, primary cells and expanded primary cells providing robust results.

They also allow researchers to make genetically matched cell lines from patients.

In the face of these setbacks, many scientists have focused on new methods of creating stem cell lines without destroying embryos.

The study involved laboratory cell lines of human leukemia and mouse models of the disease.

Many top tier journals have begun to request proof of cell line authentication from investigators.

The lack of guidelines for cell line names allows the generator of a new line determine the name individually.

However, inflammation in the intestines creates gaps between the individual cells lining the walls.

Many scientific journals require researchers who report results based on cell line experiments to use DNA profiling to establish the identity of the used cells.

We also provide cell lines for use in the manufacture and testing of vaccines.

Every time I read your articles, it's like my brain cells line up again.

Much of the money went into infrastructure that will enable the creation of additional clinical - grade cell lines, he says.

Scientists worry that too few cell lines will be available to fully determine the potential of the cells.

Researchers would need to choose an appropriate cell line to act as a host and then gradually swap out large chunks of its genome with the synthetic DNA.

They insist resources would be better spent pursuing advances through adult stem cell lines instead of allowing what they called «clone and kill» research.

All four cancer cell lines responded significantly to radiation plus the three - drug combination.

The development of tailored cell lines is also possible, in which case nutritional characteristics can be developed according to need.

We may be able to do the same thing with similar cell lines for neurons, where we can repair the damage in the brain itself.

If that turns out to be viable, you might end up with people having their own cell line almost as a matter of course 20 years from now.

I had never done it before and it worked the first time probably because I used a robust cell line.

They are a standard cell line that has become well adapted to lab work, making them very different to any cells found in the body.

It performs this critical service in embryonic development, growing organisms and in a few specialized adult cell lines, including stem cells.