Sentences with phrase «cell manipulation in»

Not exact matches

The hope one might have once placed in comparative advantage global capitalism and the internet / cell - phone wiring of all, began to look increasingly hollow, as Walmarts filled with cheap Chinese goods, real jobs went missing, real skills became rare, and the internet became known not so much for an Army of Davids shoring up our common commitment to liberty, but for mobbish comment swarms, porn, The Social Network, diversion all - the - more addictive for being personally tailored (see: the fictional fat - slobs of Wall - E, or the perpetually downward phone - gaze of our «dumb» millennials), and unprecedented possibilities for spying, defamation, and demagogic manipulation for those with access to big data.

Try as I might, I can see no signs of manipulation in the cell.

These experiments were complemented by genetic manipulations in which some mice were engineered to lack a gene known as Tap1, which is crucial for the MHC I complex to make its way to the cell surface.

In an attempt to answer this question, the researchers undertook a targeted manipulation of leukemia cell DNA in the laIn an attempt to answer this question, the researchers undertook a targeted manipulation of leukemia cell DNA in the lain the lab.

My research has implemented MFC methods for cell manipulation and molecular biology and has been applying them in collaboration with local life science researchers.

The NB activity in Alberta is far ranging, with such research as self - assembled nanostructures (M. J. Brett), single - cell cancer analysis (L. M. Pilarski), computational modeling (D. Wishart), micro-total analysis systems or lab on a chip (D. J. Harrison), cell identification and manipulation (K. Kaler), and microsystems and medical diagnostics (Backhouse).

He says that his team will work to achieve all the necessary divisions in mice before trying similar manipulations with human cells.

«New innovative method for delivering genes into cells: Modification of cell physiological function with novel parallelized electroporation of mammalian cells by using electrostatic manipulation in a water - in - oil droplet.»

In a paper published in PLOS Genetics, QUT scientists Professor Sagadevan Mundree, Dr Brett Williams and their fellow researchers have proved sugar manipulation and the controlled sacrifice of cells are keys to the native grass's survivaIn a paper published in PLOS Genetics, QUT scientists Professor Sagadevan Mundree, Dr Brett Williams and their fellow researchers have proved sugar manipulation and the controlled sacrifice of cells are keys to the native grass's survivain PLOS Genetics, QUT scientists Professor Sagadevan Mundree, Dr Brett Williams and their fellow researchers have proved sugar manipulation and the controlled sacrifice of cells are keys to the native grass's survival.

It must be capable of functioning in challenging environments in living cells, which require cutting - edge light manipulation and detection technologies optimized for light - starved conditions.

«Our findings uncover the direct coupling of these two important pathways and raise the prospect of therapeutic manipulation of the UPR to lessen the damage caused by heart attack and stroke,» said Dr. Joseph A. Hill, Professor of Internal Medicine and Molecular Biology, and senior author of the study published in the March 13 issue of Cell.

This novel technique and the information it provides have significant implications for future transport property manipulation in electronic devices featuring organic molecules, such as solar cells and light - emitting diodes.

RIKEN launched an investigation after claims of image manipulation and plagiarism surfaced regarding a research article and a letter published online in Nature on 29 January that described a new, simple way of creating stem cells called STAP, for stimulus - triggered acquisition of pluripotency.

The proposed manipulation system makes it possible to place cells in a microwell array and observe the adherence, spreading, culture, and death of the cells.

Now, researchers at Toyohashi Tech, at the Department of Mechanical Engineering, have developed a novel cell - manipulation tool that can trap and release single cells in a parallel arrangement in open - top microwells.

The researchers fabricated an array of hollow microprobes to improve throughput and achieve flexibility in single - cell manipulation.

The research, using cells from the Breast Cancer Now Tissue Bank and due to be published in Nature Communications, also shows that the epigenetic changes are inherited as long as the cell divides, and that the team's manipulations permanently and negatively affected the biology of a normal breast cell from a healthy individual.

In addition to its applicability to a large range of biological and physical science investigations, ARM technology has demonstrated excellent biocompatibility by conducting a HeLa cell viability test in which 99.2 percent of cells survived manipulatioIn addition to its applicability to a large range of biological and physical science investigations, ARM technology has demonstrated excellent biocompatibility by conducting a HeLa cell viability test in which 99.2 percent of cells survived manipulatioin which 99.2 percent of cells survived manipulation.

«The successful retrieval of memories in AD mice by increasing the number of spines for normal memory processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of neurons and their circuits for future therapies.

In contrast, the stem cells made from adult skin required no artificial manipulation.

The report apparently marks the first time genetic manipulation was used to regrow auditory hair cells in an adult mammal.

«The successful retrieval of memories in AD mice by increasing the number of spines for normal memory processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of neurons and their circuits for future therapies,» said Tonegawa in a statement.

She develops techniques and methodologies based on optical imaging, bio-sensing and single - molecule manipulation with the aim to monitor the behavior of individual biological molecules and compelxes in vitro and in live cells.

While CRISPR / Cas9 is a powerful technique for genome manipulation, two significant challenges remain: obtaining efficient delivery of the Cas9 / sgRNA complex to all cell types, and leaving no additional footprint (i.e., persistent and elevated expression of Cas9 in target cells) that could lead to off - target effects.

The work, as detailed in the journal Stem Cells, shows that only a bit of creative manipulation is needed to turn skin cells into human white blood cCells, shows that only a bit of creative manipulation is needed to turn skin cells into human white blood ccells into human white blood cellscells.

Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), are known to be vulnerable to apoptosis upon various technical manipulation, such as single cell dissociation, freezing and thawing, etc., which hinder their use for clonal isolation in gene transfer, differentiation and FACS cell sorting.

Critical assessment of incoming strains — all submissions require detailed information about method of genetic manipulation, genotype and genotyping procedures, genetic background (e.g. source of strain and ES cell used in development, number of background generations and backcross parent strain), and reproducible phenotype.

A future aspect of our mouse work is directed towards use of ES cell differentiation in culture as a model for epigenetic decisions and stem cell manipulations.

Recent papers published by groups from UC Berkeley and Stanford University have described methods for the genetic manipulation of primary human hematopoietic stem and progenitor cells (HSPCs) that require them to be maintained in vitro for anywhere from 24 hours to more than a week.

«As the only engineer in the U.S. Senate,» Sununu said, «I've been proud to protect funding for the National Science Foundation from political manipulation and fully support funding for adult and amniotic stem cell research — which has already resulted in a number of treatments that have proven to be successful in patient trials.»

In both groups of mice, the expected deleterious effects on memory and learning didn't arise if EP2 within microglial cells was absent, as a result of a genetic manipulation.

Transgenic models session Chairs V.Korinek & Z. Kozmik 16.00 Bohumil Fafílek Cell tracking and manipulation in genetically modified mice 16.30 Michaela Krausová Mouse transgenic model to study tumor progression and metastasis in the gut 17.00 coffee break 17.20 Matej Durik Rodent transgenic models of cardiovascular diseases 17.50 Jan Masek The role of Wnt / beta - catenin signaling in neural crest development: an insight from transgenic and knockout mice 19.00 dinner

«Martin's vision for genetic analysis of pluripotency, afforded by our extensive mouse resources, could lead to major advances in our understanding and manipulation of stem cell behavior in health and disease.»

To do that we will activate the pathway in adults of this zebrafish model using gene manipulation techniques, then test the health of eye cells.

Martin's vision for genetic analysis of pluripotency... could lead to major advances in our understanding and manipulation of stem cell behavior in health and disease.

The major gains in behavioral recovery and neuronal survival achieved by pre-differentiation of glial precursors to specific, beneficial astrocytic cell types prior to transplantation stresses the need to consider such manipulations as a critical component in the optimization of stem / precursor cell transplantation based therapies.

We are using biochemistry and genetics to identify the proteins that enable neurite - specific neuropeptide localization and using cell - type - specific genetic manipulations to disable that machinery and thereby probe the behavioral function of extra-synaptic peptide signaling in specific circuits.

Cell tracking and manipulation in genetically modified mice 2015-03-31 Presentation 06 Fafilek Mouse transgenic model to study tumor progression and metastasis in the gut 2015-03-24 Presentation 05 Krausova Next generation sequencing: designing experiment in transgenic

But gene therapy also needs to be carefully done and, ideally, two independent gene - manipulation systems would be used to ensure that stem cells remain firmly in control of clinicians.

The lab studies the pathways from sensory input to behavioral output by quantitative analysis of behavior under well - defined conditions, genetic manipulation of animals or individual neuronal cells, and calcium imaging from neurons in living animals.

Dsx expression level manipulation has been found to affect cell number of a sex - specific cell type in the Drosophila brain [25].

Manipulation of either FGF signalling or Nanog expression levels can alter the ratio of cell types present in this state and single Venus positive or negative cells can regenerate this equilibrium with apparently identical kinetics under self - renewing conditions.

Recently, it has been reported that glucose parameters were altered in mouse offspring produced by in vitro fertilization, intracytoplasmic sperm injection, and somatic cell nuclear transfer and that the effect was sex dependent, suggesting a sex - specific effect of in vitro exposure to media and / or mechanical manipulation on glucose homeostasis in offspring [37].

Panelists will bring experience in clinical genetics, genetic manipulation in stem cells, and disease modeling.

Our studies may also serve to enhance competence for somatic embryogenesis in recalcitrant genotypes / explants through the manipulation of overall chromatin organisation in target cells using various chromatin - related drugs.

The past century has unveiled a plethora of preclinical data that has suggested the potential of a ketogenic diet as an aid in cancer treatment.7, 8 The benefits of a ketogenic diet, and dietary manipulation in general, may be a potent adjunct to current cancer treatments by synergistically working with chemotherapy and radiation therapy to starve cancer cells, leaving them more susceptible to damage from these treatments.7 - 10

Given that fermentation in the colon is the mechanism for achieving colorectal cancer protection, via the specific contribution of n - butyrate to reduction of proliferation and induction of differentiation of the mucosal cells (Cummings 1981), it is probable that dietary manipulations which slow the fermentation rate of [RS] and dietary fiber would be of benefit in cancer protection in the distal colon and rectum.»

Topics include biosis - abiosis interface of dental implants, biomaterials in interface science, biomedical engineering interface and cell manipulation and tissue regeneration.

Manipulation of mast cell tumors, for example, when obtaining samples, can cause the release of chemicals (such as histamine) stored in the cells.

And in a world where manipulation is omnipresent — on our cell phones, our email in - boxes, our shopping carts, our kids» schools and so forth — the immutable law of supply and demand makes authenticity increasingly precious.