Sentences with phrase «cell manipulations using»

Not exact matches

«Unfortunately, these stem cell manipulations can lead to permanent genetic changes which would make them unsafe to use especially as a potential sperm or egg,» he says.

«New innovative method for delivering genes into cells: Modification of cell physiological function with novel parallelized electroporation of mammalian cells by using electrostatic manipulation in a water - in - oil droplet.»

Our new device, which enables the precise manipulation and patterning of protein crystals using surface acoustic waves, is a transformative technology for structural biologists,» said Jarrod French, an assistant professor of biochemistry and cell biology at Stony Brook University.

One area of current research is single cell manipulation and analysis using droplet microfluidics.

If mechanical stresses can influence cell fate — and Levenston's research is showing that it can — then one day it may be possible to use these biomechanical manipulations to engineer cartilage, ligament, or muscle.

The research, using cells from the Breast Cancer Now Tissue Bank and due to be published in Nature Communications, also shows that the epigenetic changes are inherited as long as the cell divides, and that the team's manipulations permanently and negatively affected the biology of a normal breast cell from a healthy individual.

To investigate how the liver responds to bile accumulation, the research team used an artificial culture system, which allowed the easy manipulation of cultured liver cells.

«An important, overarching goal of the field is to develop culture systems using primary cells with minimal ex vivo [external] manipulation.

Major studies how cancer cells hijack specific signaling pathways to spread throughout the body, using drugs and genetic manipulation to probe the inner workings of these out - of - control cells.

We use the zebrafish model to study β - cell development due to the small size and optical transparency of its embryos / larvae, as well as the ease of the genetic and chemical - genetic manipulations, including the ability to conduct large - scale small molecule screens.

The report apparently marks the first time genetic manipulation was used to regrow auditory hair cells in an adult mammal.

Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), are known to be vulnerable to apoptosis upon various technical manipulation, such as single cell dissociation, freezing and thawing, etc., which hinder their use for clonal isolation in gene transfer, differentiation and FACS cell sorting.

Critical assessment of incoming strains — all submissions require detailed information about method of genetic manipulation, genotype and genotyping procedures, genetic background (e.g. source of strain and ES cell used in development, number of background generations and backcross parent strain), and reproducible phenotype.

A future aspect of our mouse work is directed towards use of ES cell differentiation in culture as a model for epigenetic decisions and stem cell manipulations.

These guidances are aimed to clarify FDA's current thinking on regulatory classification of Human Cell Tissue Products (HCT / P) and included definitions of «same surgical procedure ``, «homologous use ``, «minimal manipulation» and «adipose tissue - derived products ``.

To do that we will activate the pathway in adults of this zebrafish model using gene manipulation techniques, then test the health of eye cells.

We've really done a lot of manipulations using cell culture.»

We are using biochemistry and genetics to identify the proteins that enable neurite - specific neuropeptide localization and using cell - type - specific genetic manipulations to disable that machinery and thereby probe the behavioral function of extra-synaptic peptide signaling in specific circuits.

Tang, Jonathan C.Y., et al. «A nanobody - based system using fluorescent proteins as scaffolds for cell - specific gene manipulation.»

But gene therapy also needs to be carefully done and, ideally, two independent gene - manipulation systems would be used to ensure that stem cells remain firmly in control of clinicians.

Our studies may also serve to enhance competence for somatic embryogenesis in recalcitrant genotypes / explants through the manipulation of overall chromatin organisation in target cells using various chromatin - related drugs.

Use mobile trading apps as the tool they were designed for but be aware of the emotional pitfalls and subconscious manipulation that occurs when you have a cell phone with a mobile trading app attached to you all day.