Sentences with phrase «cell markers in»

We compared the expression of RPE cell markers in transplanted cells in vivo against cells re-plated and cultured in parallel.

The ΔN isoforms of p63 may also serve as stem cell markers in a variety of epithelial cell types, including endometrium [30], cervix [31], breast [32], prostate [33], and in stratified squamous epithelium [21,34].

VASA is a valuable gene for the detection of germ cells differentiated from ES cells in monkeys, and the identification and characterization of germ cells derived from ES cells are possible by using reported germ cell markers in vivo, including SSEA1, OCT - 4, and VASA, in vitro as well as in vivo.

Title: Single - molecule transcript counting of stem - cell markers in the mouse intestine Authors: Itzkovitz S, Lyubimova A, Blat IC, Maynard M, van Es J, Lees J, Jacks T, Clevers H, van Oudenaarden A Date: 2011 Publication Details: Nat Cell Biol.

One common application for quantum dots is to use them as cell markers in biomedical research, says Todd Krauss, an associate professor of chemistry and optics at the University of Rochester's Institute of Optics who studies the fundamental properties of quantum dots as well as their optical properties.

The figure in question is supposed to show patterns of expression for a range of ES cell markers in the 11 cell lines.

Not exact matches

Weeks later, Yee realized that he didn't have the equipment he needed to pluck out of Ziskin's blood the rare (perhaps one in 100,000) T cells that could identify the subtle peptide markers on the surface of her cancer cells and attack the disease.

For one, it would give them three specific biological markers to hone in on: The buildup of beta amyloid and tau proteins, which cause brain plaques associated with Alzheimer's, and brain nerve cell death.

In clinical trials the treatment — which involves extracting individual patients» immune T - cells, modifying them to seek out tell - tale biological markers associated with blood cancers like aggressive lymphoma, and then pumping those modified killer cells back into the body — has shown major promise, in some cases eliminating all signs of the cancer in patients six months after treatmenIn clinical trials the treatment — which involves extracting individual patients» immune T - cells, modifying them to seek out tell - tale biological markers associated with blood cancers like aggressive lymphoma, and then pumping those modified killer cells back into the body — has shown major promise, in some cases eliminating all signs of the cancer in patients six months after treatmenin some cases eliminating all signs of the cancer in patients six months after treatmenin patients six months after treatment.

Tau helps provide structure to brain cells, is a marker for axonal damage — and is also what McKee finds spotted throughout the brains she examines in her Boston U. lab.

«We couldn't have figured out what was happening without the expertise of our collaborators at U.C. Davis, who determined the genetic sequence of every single cell marker on the cells in the lymph nodes,» says Miller.

Alcino Silva, distinguished professor of psychology at UCLA, has been using genetic markers and a highly miniaturized microscope to zero in on sets of brain cells in mice with such interconnected or «linked» memories.

Lipke, who specializes in the structure and function of cell surface markers in yeasts, says Rezende was as independent as a typical late - term Ph.D. student.

Levels of a nerve cell signaling molecule called substance P — measured in tear samples — might be a useful marker of diabetes - related nerve damage (neuropathy), suggests a study in the July issue of Optometry and Vision Science, the official journal of the American Academy of Optometry.

The researchers — James Robl, a developmental biologist and his colleagues at the University of Massachusetts at Amherst, and Steve Stice at Advanced Cell Technology in Worcester, Massachusetts — inserted a marker gene fused with a gene for resistance to the chemical neomycin into a culture of connective tissue cells called fibroblasts.

They specifically studied the length of telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood cells); the protective caps are believed to be markers of biological aging, because they shrink over time.

The MIT team also found no markers indicating that the electric fields caused abnormal inflammation, DNA damage, or cell death in the targeted tissue.

Nadeau stumbled upon one study, in mice, describing how environmental factors can tag Foxp3 with chemical markers that tell T - cell precursors to switch the gene on or off.

In addition, scientists found an increase in the markers for the growth of cancerous cells and liver inflammation in both groups exposed to the carcinogeIn addition, scientists found an increase in the markers for the growth of cancerous cells and liver inflammation in both groups exposed to the carcinogein the markers for the growth of cancerous cells and liver inflammation in both groups exposed to the carcinogein both groups exposed to the carcinogen.

«We can direct them to CD45, a cell marker which is exclusively expressed in the blood system.

In 1988 and 1989 at Edouard Herriot Hospital, two fetuses whose blood cell markers showed they had severe immune disorders became the first ever to receive a cell transplant.

They injected this handcrafted virus into rats and found that the marker gene was indeed active only in smooth muscle cells.

He proved it in 2003 by first X-raying mice to kill off all the stem cells in their bone marrow, then repopulating the bone with stem cells tagged with a fluorescent marker.

By measuring levels of the stress hormone cortisol, plus other chemical markers, the team found that the task caused more cell damage in the women who were already stressed.

Blood stem cells in the bone marrow have been labeled with a fluorescent marker protein.

When Busch turned on the marker in adult animals, it became visible that at least one third (approximately 5000 cells) of a mouse's hematopoietic stem cells produce differentiated progenitor cells.

In mice, this form of lipodystrophy was also characterized by «whitening» of brown fat cells, a loss of white fat, and signs of metabolic syndrome, including insulin resistance, fat tissue inflammation, dyslipidemia (elevated cholesterol and fat), increased resting energy use, and increased markers of cardiovascular disease.

The team looked for these cells in nonliving brain samples in two ways: molecular markers that tag dividing cells and young nerve cells, and telltale shapes of newborn cells.

But in the 1 September issue of the Journal of Clinical Investigation, cardiologist Michael Parmacek and his colleagues at the University of Chicago describe how they deleted two genes from the common cold virus to make it unable to cause any sniffling or fever, then replaced them with a marker gene that turns out an easily detected protein and the SM22 promoter, which turns on expression of genes in smooth muscle cells that surround arteries.

Part of the cytoskeleton, vimentin gives flexibility and structure to the cell, but it is also a marker of epithelial - mesenchymal transition (EMT), which is considered a crucial event for metastasis in epithelial tumors.

Their work elucidates a dynamic, two - step mechanism in females whereby B cells lacking the markers of X chromosome inactivation regain these modifications during B cell activation, in a process involving the transcription factor YY1.

The results showed that, when applied, a long - term inhibition of Rho - kinase signaling increased the expressions of chondrocyte - specific genes and differentiation markers in human chondrosarcoma 2/8 cells.

A specific genetic marker influences response to therapy in the early stages of RA; a link thought to be due to the gene activating a cell - signalling protein involved in the inflammatory disease process.

When activated by inflammatory markers in the gut, it sends a signal to the brain, where immune cells produce proteins such as IL - 6, leading to increased metabolism (and hence decreased levels) of the «happiness hormone» serotonin in the brain.

In a similar way to how they work in other cells, epigenetic markers push PGCs to their fate during embryonic development, but PGCs are unique because when they develop into sperm and eggs, the epigenetic markers are eraseIn a similar way to how they work in other cells, epigenetic markers push PGCs to their fate during embryonic development, but PGCs are unique because when they develop into sperm and eggs, the epigenetic markers are erasein other cells, epigenetic markers push PGCs to their fate during embryonic development, but PGCs are unique because when they develop into sperm and eggs, the epigenetic markers are erased.

New markers suggested include total mass of hemoglobin, altered expression of genes related to red blood cell metabolism, ironomics, storage lesions, and the presence of plasticizers from blood bags in athlete urine samples.

Now scientists like Perls are sifting through millions of DNA markers to spot the constellation of longevity genes that's carried in every cell of these centenarians» bodies.

Kelley and his team also used mice with fluorescent markers in different cells of the ear followed by next generation sequencing.

Although that marker, called IL21, had not previously been associated with autoimmune diseases, the gene that produces it sits right in the stretch of DNA known to make these mice vulnerable to diabetes, suggesting that IL21 might make a drug target, says Sarvetnick.Furthermore, by giving the animals a shot of dead bacteria — similar to an immunization in humans — when they were newborns, Sarvetnick and her colleagues prevented a surfeit of CD4 + and CD8 + cells.

In healthy breast tissue, the percentage of cells expressing molecular marker Ki67 (green) and p27 (red) was low.

The researchers also observed increased tryptase, another marker of mast cell degranulation, in skin around the affected area.

The neurons express a pan neuronal marker Map2 in green and a percentage of the cells express a marker for inhibitory neurons, GABA, in red.

Once the stem cells are created, Niklason relies on different chemical markers left behind in the decellularized lungs to guide the stem cells to their correct locations.

In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.

Researchers from BUSM and the University of Cyprus compared the markers on the surface of the cancer cells to gene expression profile of breast tumors deposited by researchers in international public databases and found that a molecule named IL13RA2 (IL13R alpha2) was abundant in metastatic or late - stage BLBC.

They found that women were five times as likely to develop cancer if they had a higher percentage of Ki67, a molecular marker that identifies proliferating cells, in the cells that line the mammary ducts and milk - producing lobules.

This way, Professor Henrik Zetterberg and his colleagues could show that a special nerve cell protein, called tau, at elevated levels in the blood is a marker of concussion.

In order to locate all gene switches, the Freiburg research team used modern sequencing methods to examine the entire genome — DNA, epigenetic markers and RNA — during the development, maturation and disease of human cardiac muscle cells.

In 30 fish, Kaufman spotted a small cluster of green - glowing cells about the size of the head of a Sharpie marker — and in all 30 cases, these grew into melanomaIn 30 fish, Kaufman spotted a small cluster of green - glowing cells about the size of the head of a Sharpie marker — and in all 30 cases, these grew into melanomain all 30 cases, these grew into melanomas.

Clipped H3.3 may be a marker of cells that stop proliferating and has implications for cancer, in particular cancers like melanoma that have a senescence phase.»