Sentences with phrase «cell markers like»

Corresponding to upregulated TRF2 expression at 80μM, stem cell markers like CD44 and Oct4 were also observed to be upregulated in Clonospheric HCT116 as compared to Parental HCT116 (Fig. 3a and 3b) Decreasing CD24 expression in clonospheric HCT116 was observed which correlated well with increased stem cell expression (Fig. 3b).

There are no specific markers to identify them; however, they are negative for hematopoietic cell markers like CD34 / 45 / HLA - DR and express CD90 / 73/105 on their surface 2, 3, 4.

Not exact matches

In clinical trials the treatment — which involves extracting individual patients» immune T - cells, modifying them to seek out tell - tale biological markers associated with blood cancers like aggressive lymphoma, and then pumping those modified killer cells back into the body — has shown major promise, in some cases eliminating all signs of the cancer in patients six months after treatment.

Now scientists like Perls are sifting through millions of DNA markers to spot the constellation of longevity genes that's carried in every cell of these centenarians» bodies.

Clipped H3.3 may be a marker of cells that stop proliferating and has implications for cancer, in particular cancers like melanoma that have a senescence phase.»

This biomechanical marker could be used as a rapid and cost - effective approach to enrich for stem - like cells in corneal transplant tissue.

For example, labeling of these cells with stem - like cell associated markers (p63, nestin, and telomerase) have heavily implicated these cells as stem cells [13].

Methods: Human corneas with attached scleral rims were obtained from eye banks and were assayed for telomerase activity and BrdU (bromodeoxyridine) incorporation to determine, respectively, the presence of a stem - like cell marker and replicative activity.

When overexpressed together in developing Xenopus embryos by RNA microinjection, these genes can induce eye - like structures as defined by the expression of markers for some retinal cell classes [7].

Oct - 4 is a transcription factor which has been reported to be involved in various cancers and is also marker for cancer stem cell like population [34, 35].

Solid tumours are reported to possess a sub set of cells called Side Population expressing various stem like cell markers, self - renewal capacity and ability to give rise to differentiated cells [23, 24].

Since very few studies have demonstrated the formation of macro-metastasis from low numbers of sorted CSCs and currently proposed CSC markers might not be sufficient to identify all stem cell populations [13], we believe that our study presents a promising approach to isolate stem - like and metastatic breast CSCs as opposed to the cell - sorting strategy based on putative stem cell surface markers.

He used a fluorescent marker called GFP (Green Fluorescent Protein) to label the suspected prion - determining domains of these proteins and looked to see if they aggregated in cells - a sign that they may be misfolding and an indication of prion - like activity.

Using clinical samples we would like to create an immunoprofile of activated B cells and memory B cells that may provide prognostic markers for dengue immunity and / or immunopathology.

For definitive endoderm differentiation, spontaneously formed EBs on day 6 were plated onto matrigel - coated dishes and maintained in a low concentration of fetal bovine serum (FBS) in combination with a high concentration of recombinant Activin A. Scale - like cells appeared (Figure 5A), which were positive for definitive endoderm markers such as Foxa2, Sox17 and Gata4.

Neural crest - like stem cells (NCLSC) share many properties with aggressive melanoma cells, such as high migratory capabilities and expression of neural crest markers.

Here we consider two surface markers thought to define these cells in mice, CD8 and Killer cell lectin - like receptor G1 (KLRG1), and a means we developed to remove these cells from the blood of aged C57BL / 6 mice.

Here we show that the frequency of CD8 + T cells expressing the inhibitory killer cell lectin - like receptor G1 (KLRG1), a marker of cells unable to undergo further clonal expansion, was markedly elevated in CD8 + T cells from old donors.

She plans to test whether or not molecules designed to target the marker can block the signaling necessary for maintaining the cells» stem - like properties, which could lead to new antibody - based immunotherapies for breast cancer.

Sixty three studies were reviewed and consumption of alcohol was investigated together with recognized physical markers for heart disease like inflammation levels, cholesterol, the condition of blood vessels and fat cells.

With this combination of natural food protocols, Cellect and the antibody treatment I have seen a dramatic reduction in my cancer marker (a blood test result which measures a protein like cell which is an indicator of multiple myeloma activity).

Neuroendocrine tumor markers and enterochromaffin - like cell hyper / dysplasia in type 1 diabetes.

When uncovering more research on it, you will find that C125 inflammatory markers and immune cells like TCells, NK Cells are either higher or lower than they should be when you have endometricells like TCells, NK Cells are either higher or lower than they should be when you have endometriCells are either higher or lower than they should be when you have endometriosis.