Using ultra-high resolution laser - tracking («nano - tracking»), we invented a new way («microrheology») to
measure cell mechanics during physiological processes.
Now a more fine - grained picture of adhesion mechanics is emerging, thanks to a new tool developed in Illinois in recent years called a «tension gauge tether,» which allows scientists to measure
cell mechanics at the single - molecule level.
For Kunz and his team, creating the Heartmate PHP provided a new opportunity to pursue technologies outside their normal expertise, including circulatory system physiology,
blood cell mechanics, and biochemistry.
Jens - Christian Roeper (Eaton, MPG)-- «The influence
of cell mechanics, cell - cell interactions and proliferation on epithelial packing» (2009)
Mechanotransduction The effects of extracellular matrix stiffening on endothelial cell health Cynthia Reinhart - King, Cornell University The effects of membrane cholesterol and extracellular matrix elasticity on vascular smooth
muscle cell mechanics and migration Zhongkui Hong, University of South Dakota
Next, we describe the biophysical tools that have been developed in recent years to characterize and model
cancer cell mechanics.
A micropipette aspiration set up can easily be coupled to high - resolution fluorescence confocal microscopes to
relate cell mechanics to sub-cellular processes.
A central aim of our group is to reveal active and passive contributions to the effective cellular shear modulus conventionally used
in cell mechanics.